Southeast Missouri Kid friendly Holidays 2026

Photo by JG Morris

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Top Kid friendly Southeast Missouri Hotels

Drury Inn & Suites Sikeston, MO

2608 East Malone Ave, Miner Sikeston MO

4 hours drive from Mark Twain National Forest

Stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the breakfast and the helpful staff in ...

9.6/10 Exceptional! (1,001 reviews)

"EVERYONE was EXTREMELY FRIENDLY"

Reviewed on 30 Sept 2026

Best Western Plus Sikeston I-55

120 S Interstate Drive Sikeston MO

4 hours drive from Mark Twain National Forest

Stay at this hotel in Sikeston. Enjoy free breakfast, free parking and a fitness centre. Our guests praise the breakfast and the helpful staff in their reviews. ...

Drury Inn & Suites Cape Girardeau

3303 Campster Drive Cape Girardeau MO

5 hours drive from Mark Twain National Forest

Stay at this business-friendly hotel in Cape Girardeau. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the helpful staff and the clean ...

9.4/10 Exceptional! (1,001 reviews)

"EVERYONE was EXTREMELY FRIENDLY even maintenance all FRIENDLY"

Reviewed on 2 Oct 2026

See all 687 properties in Southeast Missouri

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.