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Top Honeymoon Eastern Piedmont Hotels

The Mayton

301 S Academy St Cary NC

37 min drive from Duke University

Stay at this boutique hotel in Cary. Enjoy free Wi-Fi, free parking and breakfast (surcharge). Our guests praise the helpful staff in their reviews. Popular ...

9.4/10 Exceptional! (769 reviews)

"Amazing stay, entire experience was top notch. Loved walking around the park, grabbing drinks at the park and walking around. The Wife and I didn’t want to leave!"

Reviewed on 30 Jun 2026

The Umstead Hotel and Spa

100 Woodland Pond Dr Cary NC

29 min drive from Duke University

Stay at this luxury resort in Cary. Enjoy free Wi-Fi, free parking and an outdoor pool. Our guests praise the helpful staff in their reviews. Popular attractions ...

9.6/10 Exceptional! (786 reviews)

"Exceptional!"

Reviewed on 1 Jul 2026

21c Museum Hotel Durham

111 North Corcoran Street Durham NC

10 min walk from Duke University

Stay at this hotel in Durham. Enjoy free Wi-Fi, breakfast (surcharge) and room service. Our guests praise the helpful staff in their reviews. Popular attractions ...

8.4/10 Very good! (1,002 reviews)

"All staff were extremely wonderful Stan the man was the best"

Reviewed on 27 Jun 2026

See all 4,969 properties in Eastern Piedmont

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.