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Top Cheap Panhandle Plains Hotels

Studio 6 Amarillo, TX – West Medical Center

6801 W Interstate 40, Amarillo, TX

4 hours drive from Texas Tech University

Stay at this business-friendly hotel in Amarillo. Enjoy free Wi-Fi, free parking and a 24-hour front desk. Our guests praise the breakfast and the pool in their ...

7.4/10 Good! (1,000 reviews)

"Clean"

Reviewed on 14 Jul 2025

Days Inn by Wyndham Amarillo East

1701 I-40E, I-40 Exit 71 Ross-Osage, Amarillo, TX

4 hours drive from Texas Tech University

Stay at this business-friendly hotel in Amarillo. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the helpful staff and the clean rooms ...

6.6/10 (1,004 reviews)

"Still waiting for my deposit refund. Not done as they said it will be done after checkout"

Reviewed on 17 Jul 2025

Extend-a-Suites - Extended Stay, I-40 Amarillo West

3411 I-40 W, Amarillo, TX

4 hours drive from Texas Tech University

Stay at this hotel in Amarillo. Enjoy free Wi-Fi, free parking and a 24-hour front desk. Popular attractions The Galleries at Sunset Center and Amarillo Little ...

4.8/10 (1,001 reviews)

"The area has stuff littering the veranda as you pull in, it is obvious they are renovating and i was told there are only a total of 12 rooms available for check-in out of 300"

Reviewed on 10 May 2025

See all 2,051 properties in Panhandle Plains

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.