Top Adventure Mesopotamia Hotels

Iguazu Grand Resort Spa & Casino

Route 12 Km 1640, Puerto Iguazú, Misiones

17 hours drive from Termas de Federacion

Stay at this 5-star luxury hotel in Puerto Iguazú. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the helpful staff in their reviews. Popular ...

9/10 Wonderful! (556 reviews)

"They upgraded us to a beautiful suite. It was a great stay!"

Reviewed on 16 Aug 2025

Hotel das Cataratas, A Belmond Hotel, Iguassu Falls

Rodovia Br 469 Km 32, Iguassu National Park, Foz do Iguaçu, PR

17 hours drive from Termas de Federacion

Stay at this 5-star luxury hotel in Foz do Iguaçu. Enjoy free breakfast, free Wi-Fi and a full-service spa. Our guests praise the helpful staff and the property ...

9.8/10 Exceptional! (1,000 reviews)

World class perfection.

"One of the finest hotels in the world and the best hotel that I have ever stayed at. Exquisite attention to detail. The staff go out of their way to make sure everything you wish for is done. They are kind, attentive, and courteous without being overbearing. Just a remarkable experience. Everything ..."

Reviewed on 17 Aug 2025

Gran Melia Iguazú

Parque Nacional Iguazu, Puerto Iguazú, Misiones

17 hours drive from Termas de Federacion

Stay at this luxury hotel in Puerto Iguazú. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the helpful staff and the property condition ...

9/10 Wonderful! (1,000 reviews)

"My stay was very enjoyable and the service and attentiveness from the staff was amazing. The convenience of being right by the paths and within the park made it worth it."

Reviewed on 3 Aug 2025

See all 500 properties in Mesopotamia

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.