Search Hotels in West Main Historic District, Louisville

Start date: Check-in selected.
To Date
End date: Check-out

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
12 Dec - 13 Dec
Tomorrow
13 Dec - 14 Dec
This weekend
12 Dec - 14 Dec
Next weekend
19 Dec - 21 Dec

Filter by

Guest rating
Guest rating
Star rating

Our top choices for West Main Historic District hotels

4 restaurants, breakfast, lunch, dinner served; American cuisine
Galt House Hotel Trademark Collection by Wyndham

Galt House Hotel Trademark Collection by Wyndham

Galt House Hotel Trademark Collection by Wyndham
4.0 star property
West Main Historic District
9.0 out of 10, Wonderful, (3852)
"Beautiful room and great hospitality. "
United States
Chase
The price is ₹12,046
₹14,173 total
includes taxes & fees
17 Dec - 18 Dec
Galt House Hotel Trademark Collection by Wyndham
Sauna, body treatments, aromatherapy, hot stone massages
Omni Louisville Hotel

Omni Louisville Hotel

Omni Louisville Hotel
4.0 star property
West Main Historic District
9.2 out of 10, Wonderful, (1728)
"This is a beautiful hotel in a great location. Very kind staff and helpful with directions."
United States
Bonnie
The price is ₹15,110
₹17,779 total
includes taxes & fees
1 Jan - 2 Jan 2026
Omni Louisville Hotel
Exterior
Holiday Inn Express & Suites Louisville Downtown by IHG

Holiday Inn Express & Suites Louisville Downtown by IHG

Holiday Inn Express & Suites Louisville Downtown by IHG
2.5 star property
West Main Historic District
8.8 out of 10, Excellent, (1652)
"Great place I would definitely book again"
United States
Lisa
The price is ₹7,410
₹8,719 total
includes taxes & fees
16 Dec - 17 Dec
Holiday Inn Express & Suites Louisville Downtown by IHG
Dinner served
Embassy Suites Louisville Downtown

Embassy Suites Louisville Downtown

Embassy Suites Louisville Downtown
4.0 star property
West Main Historic District
9.0 out of 10, Wonderful, (1107)
"Staff was courteous, hotel was beautiful and clean, and breakfast was amazing!"
United States
Shunskis
The price is ₹10,049
₹11,823 total
includes taxes & fees
28 Dec - 29 Dec
Embassy Suites Louisville Downtown
Breakfast and dinner served
Hilton Garden Inn Louisville Downtown

Hilton Garden Inn Louisville Downtown

Hilton Garden Inn Louisville Downtown
3.5 star property
West Main Historic District
8.4 out of 10, Very good, (1006)
"Great stay! "
United States
THERESA
The price is ₹8,603
₹10,122 total
includes taxes & fees
21 Dec - 22 Dec
Hilton Garden Inn Louisville Downtown
Exterior
Homewood Suites by Hilton Louisville Downtown, KY

Homewood Suites by Hilton Louisville Downtown, KY

Homewood Suites by Hilton Louisville Downtown, KY
3.0 star property
West Main Historic District
9.2 out of 10, Wonderful, (1001)
"The room was wonderful and the staff exceptional."
United States
Daniel
The price is ₹9,037
₹10,633 total
includes taxes & fees
20 Dec - 21 Dec
Homewood Suites by Hilton Louisville Downtown, KY
Lobby
Towneplace Suites By Marriott Louisville Downtown

Towneplace Suites By Marriott Louisville Downtown

Towneplace Suites By Marriott Louisville Downtown
3.0 star property
West Main Historic District
9.2 out of 10, Wonderful, (509)
"Great rooms "
United States
Ayden
The price is ₹8,766
₹10,314 total
includes taxes & fees
28 Dec - 29 Dec
Towneplace Suites By Marriott Louisville Downtown
Free daily buffet breakfast
SpringHill Suites by Marriott Louisville Downtown

SpringHill Suites by Marriott Louisville Downtown

SpringHill Suites by Marriott Louisville Downtown
3.0 star property
West Main Historic District
8.4 out of 10, Very good, (1001)
"The staff was great and the hotel was really nice. Great place to stay."
United States
James
The price is ₹8,404
₹9,888 total
includes taxes & fees
15 Dec - 16 Dec
SpringHill Suites by Marriott Louisville Downtown
Reception
Residence Inn by Marriott Louisville Downtown

Residence Inn by Marriott Louisville Downtown

Residence Inn by Marriott Louisville Downtown
3.0 star property
West Main Historic District
8.8 out of 10, Excellent, (1001)
"Clean room, great location,walkable to everything, parking in and out no hassle, very nice staff!"
United States
Russell
The price is ₹8,404
₹9,888 total
includes taxes & fees
17 Dec - 18 Dec
Residence Inn by Marriott Louisville Downtown
Bar (on property)
Holiday Inn Louisville Downtown by IHG

Holiday Inn Louisville Downtown by IHG

Holiday Inn Louisville Downtown by IHG
3.0 star property
West Main Historic District
8.0 out of 10, Very good, (762)
"Overall, a really nice stay"
United States
Melissa
The price is ₹7,049
₹8,293 total
includes taxes & fees
18 Dec - 19 Dec
Holiday Inn Louisville Downtown by IHG
Lobby
Seelbach Hilton Louisville Downtown

Seelbach Hilton Louisville Downtown

Seelbach Hilton Louisville Downtown
4.0 star property
West Main Historic District
8.6 out of 10, Excellent, (1001)
"Excellent location and a great lobby bar with a top notch bourbon selection. "
United States
vincent
The price is ₹10,370
₹12,201 total
includes taxes & fees
22 Dec - 23 Dec
Seelbach Hilton Louisville Downtown
Dining
Cambria Hotel Louisville Downtown-Whiskey Row

Cambria Hotel Louisville Downtown-Whiskey Row

Cambria Hotel Louisville Downtown-Whiskey Row
3.0 star property
West Main Historic District
9.4 out of 10, Exceptional, (1002)
"All the staff we met were really nice! The rooms are clean and spacious."
United States
Kelly Anne
The price is ₹7,877
₹9,269 total
includes taxes & fees
25 Dec - 26 Dec
Cambria Hotel Louisville Downtown-Whiskey Row
Exterior
Fairfield Inn & Suites by Marriott Louisville Downtown

Fairfield Inn & Suites by Marriott Louisville Downtown

Fairfield Inn & Suites by Marriott Louisville Downtown
2.5 star property
West Main Historic District
8.2 out of 10, Very good, (1001)
"Clean rooms and friendly staff. "
United States
Reba
The price is ₹7,591
₹8,931 total
includes taxes & fees
15 Dec - 16 Dec
Fairfield Inn & Suites by Marriott Louisville Downtown
Breakfast, lunch and dinner served
Hyatt Regency Louisville

Hyatt Regency Louisville

Hyatt Regency Louisville
4.0 star property
West Main Historic District
8.8 out of 10, Excellent, (1001)
"Enjoyed our stay "
United States
Jedediah
The price is ₹10,483
₹12,334 total
includes taxes & fees
23 Dec - 24 Dec
Hyatt Regency Louisville
Bar (on property)
Moxy Louisville Downtown

Moxy Louisville Downtown

Moxy Louisville Downtown
3.5 star property
West Main Historic District
9.2 out of 10, Wonderful, (696)
"Awesome location and the staff was super friendly"
United States
Kelly
The price is ₹9,398
₹11,058 total
includes taxes & fees
19 Dec - 20 Dec
Moxy Louisville Downtown
Restaurant
Louisville Marriott Downtown

Louisville Marriott Downtown

Louisville Marriott Downtown
4.0 star property
West Main Historic District
9.0 out of 10, Wonderful, (1000)
"Very nice hotel. Great stay!"
United States
Brad
The price is ₹15,465
₹18,197 total
includes taxes & fees
19 Dec - 20 Dec
Louisville Marriott Downtown
Standard Room, 2 Double Beds, Non Smoking | Desk, blackout curtains, soundproofing, iron/ironing board
Econo Lodge Louisville Downtown

Econo Lodge Louisville Downtown

Econo Lodge Louisville Downtown
2.0 star property
West Main Historic District
7.2 out of 10, Good, (1003)
"Nice hotel with a great location near Whiskey Row. This is my 3rd stay at this hotel and will definitely come back again"
United States
Nicholas
The price is ₹5,435
₹6,394 total
includes taxes & fees
28 Dec - 29 Dec
Econo Lodge Louisville Downtown
View from room
Aloft Louisville Downtown

Aloft Louisville Downtown

Aloft Louisville Downtown
3.0 star property
West Main Historic District
9.0 out of 10, Wonderful, (1003)
"Good"
United States
Les
The price is ₹8,743
₹10,287 total
includes taxes & fees
19 Dec - 20 Dec
Aloft Louisville Downtown
Deluxe Single Room, 1 King Bed, River View | View from room
The Grady

The Grady

The Grady
4.0 star property
West Main Historic District
9.4 out of 10, Exceptional, (1000)
"The location was outstanding and atmosphere was very nice."
United States
Malcolm
The price is ₹13,094
₹15,407 total
includes taxes & fees
19 Dec - 20 Dec
The Grady
Exterior
Hotel Distil, Autograph Collection

Hotel Distil, Autograph Collection

Hotel Distil, Autograph Collection
4.0 star property
West Main Historic District
9.6 out of 10, Exceptional, (428)
"Great location. Great restraunt, great staff. Pleasurable experience!"
United States
Harrison
The price is ₹15,826
₹18,621 total
includes taxes & fees
27 Dec - 28 Dec
Hotel Distil, Autograph Collection
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Where to stay in West Main Historic District

Find the best West Main Historic District areas for the activities you enjoy most.
Louisville showing street scenes and signage as well as a small group of people

Downtown Louisville

The cultural heart of the city beats with baseball, boxing and music, with sporting fields, live bands and a center for Muhammad Ali, the city’s most famous son.

Fairgrounds

While visiting Fairgrounds, you might make a stop by sights like Freedom Hall and Kentucky Kingdom.

Jeffersontown

Jeffersontown is known for its abundant dining options, and you can plan a trip to Bluegrass Indoor Karting and Jeffersontown Commons Shopping Center while you're in town.

St. Matthews

St. Matthews is noteworthy for its shopping, and you can make a stop at top attractions like Mall St. Matthews and Saint Matthews Pavilion Shopping Center.

Conrad Caldwell House showing signage and heritage elements

Old Louisville

Old Louisville is known for its ample dining options, and you can make a stop by Ohio River Valley and Conrad-Caldwell House Museum while in the area.

Top West Main Historic District Hotel Reviews

Omni Louisville Hotel

Omni Louisville Hotel

10/10 Excellent
"We had booked a suite for the night of our wedding and when checking in, the staff (Matt & Lina) were awesome! Matt upgraded our room to the Presidential Suite and made the night even better! Thank you all for the wonderful experience!"
Matt 1-night trip
Posted 11 hours ago
Omni Louisville Hotel

Explore a world of travel with Expedia

Frequently asked questions

What's it like in West Main Historic District?
Travellers love the West Main Historic District neighbourhood for its stunning river views, array of dining options and sporting events. Are you looking for West Main Historic District travel tips? Make sure that you visit Frazier International History Museum and Louisville Slugger Museum while you're in the neighbourhood.
Where is the best hotel for a stay in West Main Historic District?
Based on Expedia customer reviews, The Grady is the highest ranked property in West Main Historic District. This hotel is a short 5-minute walk from Louisville Slugger Museum, and it offers a restaurant and a bar. Other top choices in the neighbourhood include Omni Louisville Hotel and Hotel Distil, Autograph Collection.
How many hotels will I be able to find in the West Main Historic District area?
If you're searching for places to stay in Louisville, Expedia has something to meet your needs with 237 West Main Historic District hotels and other accommodation options to choose from.
If I need to cancel my hotel reservation in West Main Historic District, will I receive a refund?
Yes! You'll find that most hotel room reservations are fully refundable as long as you cancel before the accommodation's cancellation deadline, which often is within 24-48 hours of your scheduled arrival. If your reservation is non-refundable, you might be able to still cancel and get a refund within a 24-hour period of your booking. Enter your dates, click on "Search", then filter by "fully refundable" to view the best options available in West Main Historic District.
What is there to do around this Louisville neighbourhood?
For cultural attractions in West Main Historic District, head to Flame Run Glass Studio and Gallery, Frazier International History Museum and Louisville Slugger Museum. Louisville Science Center and 21c Museum Hotel are also a couple of places to visit in the neighbourhood. Kentucky Peerless Distilling Co., Louisville Glassworks and SAR Genealogical Research Library: NSSAR Library are just a few of the places to visit in and around West Main Historic District. While you're out sightseeing, Kentucky Museum of Art and Craft and Russell District Marker are a couple of additional sights to visit in Louisville.