The Best Hotels Closest to 21c Museum Hotel in Louisville - 2026 Updated Prices

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Our top choices for 21c Museum Hotel hotels

55-inch flat-screen TV with satellite channels, TV

1. Hotel Distil, Autograph Collection

Downtown Louisville, 0.8 km from 21c Museum Hotel

Adam

₹23,540

₹27,697 total

includes taxes & fees

11 Oct - 12 Oct

2. The Brown Hotel

Downtown Louisville, 1.2 km from 21c Museum Hotel

Melanie

₹13,590

₹15,991 total

includes taxes & fees

20 Sept - 21 Sept

3 bars/lounges, cocktail bar, lobby lounge

Outdoor pool, open 6:00 AM to 10:00 PM, pool cabanas (surcharge)

3. Omni Louisville Hotel

Downtown Louisville, 0.8 km from 21c Museum Hotel

Kara

₹26,769

₹31,496 total

includes taxes & fees

2 Oct - 3 Oct

2 restaurants; breakfast and dinner served

Desk, laptop workspace, free WiFi, bed sheets

4. Tempo By Hilton Louisville Downtown Nulu

Phoenix Hill, 2 km from 21c Museum Hotel

Maria

₹14,623

₹17,205 total

includes taxes & fees

5 Oct - 6 Oct

5. DuPont Mansion Bed & Breakfast

Old Louisville, 2.8 km from 21c Museum Hotel

Casey

₹17,465

₹20,271 total

includes taxes & fees

21 Sept - 22 Sept

Signature Suite, 1 Queen Bed, Non Smoking | Premium bedding, down duvets, memory-foam beds, laptop workspace

6. Stellar Suites

East Market District, 2.2 km from 21c Museum Hotel

Benton

₹9,427

₹15,950 total

includes taxes & fees

4 Oct - 5 Oct

7. Homewood Suites by Hilton Louisville Downtown, KY

Downtown Louisville, 0.1 km from 21c Museum Hotel

Steve

₹13,688

₹16,106 total

includes taxes & fees

12 Oct - 13 Oct

Deluxe Single Room, 1 King Bed, City View | Frette Italian sheets, premium bedding, free WiFi, bed sheets

8. The Grady

Downtown Louisville, 0.1 km from 21c Museum Hotel

Bruce

₹16,754

₹19,713 total

includes taxes & fees

11 Oct - 12 Oct

Desk, laptop workspace, iron/ironing board, free WiFi

9. Cambria Hotel Louisville Downtown-Whiskey Row

Downtown Louisville, 1.2 km from 21c Museum Hotel

Larry

₹11,428

₹13,447 total

includes taxes & fees

18 Oct - 19 Oct

Room (Asleep in the Cyclone) | Premium bedding, down duvets, minibar, in-room safe

Breakfast, lunch, dinner and brunch served

10. 21c Museum Hotel Louisville

Downtown Louisville, < 0.1 km from 21c Museum Hotel

Candice

₹18,662

₹22,437 total

includes taxes & fees

11 Oct - 12 Oct

11. Hotel Bourré Bonne Louisville, Curio Collection by Hilton

Downtown Louisville, 0.8 km from 21c Museum Hotel

Breeana

₹20,362

₹23,958 total

includes taxes & fees

28 Sept - 29 Sept

12. Aloft by Marriott Louisville Downtown

Downtown Louisville, 0.9 km from 21c Museum Hotel

Angela

₹12,993

₹15,288 total

includes taxes & fees

4 Oct - 5 Oct

Room, 2 Queen Beds | Premium bedding, pillow-top beds, desk, laptop workspace

13. Moxy Louisville Downtown

Downtown Louisville, 0.9 km from 21c Museum Hotel

Bryan

₹12,272

₹14,439 total

includes taxes & fees

4 Oct - 5 Oct

14. Towneplace Suites By Marriott Louisville Downtown

Downtown Louisville, 0.3 km from 21c Museum Hotel

Scott

₹11,697

₹13,763 total

includes taxes & fees

11 Oct - 12 Oct

15. AC Hotel Louisville Downtown

East Market District, 2 km from 21c Museum Hotel

Connie

₹14,151

₹16,650 total

includes taxes & fees

4 Oct - 5 Oct

2 bars/lounges, cocktail bar, rooftop bar

Hypo-allergenic bedding, in-room safe, desk, laptop workspace

16. Hotel Genevieve part of JdV by Hyatt

East Market District, 2 km from 21c Museum Hotel

Rebekah

₹14,573

₹17,147 total

includes taxes & fees

4 Oct - 5 Oct

4 restaurants; breakfast, lunch and dinner served

In-room safe, desk, laptop workspace, iron/ironing board

Suite, 1 King Bed, Balcony (Legendary) | Living area | Flat-screen TV

17. Galt House Hotel Trademark Collection by Wyndham

Downtown Louisville, 0.5 km from 21c Museum Hotel

Saud

₹15,572

₹18,322 total

includes taxes & fees

4 Oct - 5 Oct

18. Central Park Bed & Breakfast

Old Louisville, 2.9 km from 21c Museum Hotel

Angie

₹14,900

₹17,294 total

includes taxes & fees

20 Sept - 21 Sept

19. Embassy Suites Louisville Downtown

Downtown Louisville, 0.8 km from 21c Museum Hotel

Maurica

₹15,645

₹18,408 total

includes taxes & fees

11 Oct - 12 Oct

Suite (VIP) | Premium bedding, in-room safe, desk, blackout curtains

20. Hyatt Regency Louisville

Downtown Louisville, 0.6 km from 21c Museum Hotel

Sandra

₹17,066

₹20,080 total

includes taxes & fees

30 Sept - 1 Oct

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Compare popular hotels close to 21c Museum Hotel

Property	Property class	Guest rating
Hotel Distil, Autograph Collection	9.6 Exceptional 505 reviews	View
The Brown Hotel	9.4 Exceptional 1,301 reviews	View
Omni Louisville Hotel	9.4 Exceptional 2,147 reviews	View
Tempo By Hilton Louisville Downtown Nulu	9.4 Exceptional 1,120 reviews	View
DuPont Mansion Bed & Breakfast	9.6 Exceptional 147 reviews	View

Top 21c Museum Hotel Hotel Reviews

Galt House Hotel Trademark Collection by Wyndham

10/10 Excellent

"This place is clean the pool is nice and the bars 😁"

Towneplace Suites By Marriott Louisville Downtown

10/10 Excellent

"Very good"

Radisson Hotel Louisville North

10/10 Excellent

"Staff was nice"

The Grady

10/10 Excellent

"Nice room"

Holiday Inn Express & Suites Louisville Downtown by IHG

10/10 Excellent

"Great location and very friendly staff"

Hyatt Regency Louisville

10/10 Excellent

"Downtown- close to “Fourth Street” & the conference that I was visiting for."

Embassy Suites Louisville Downtown

8/10 Good

"Nice"

Louisville Marriott Downtown

10/10 Excellent

"Hotel was beautiful and centrally located . Staff was helpful and friendly"

Moxy Louisville Downtown

10/10 Excellent

"Was a great place and great experience with the staff. Highly recommend this place"

Other attractions near 21c Museum Hotel

A historic building with ornate architecture, including columns and decorative moldings.

Louisville Science Center

7.8/10 (6 reviews)

Science is all around us, inescapable. Understand important elements of our world with a visit to this science center for all ages.

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Kentucky Center for the Performing Arts

8.8/10 (49 reviews)

Enjoy a pleasant night at the opera or attend a concert, live dance or stage production at this glass-fronted venue in downtown Louisville.

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A modern building with a cylindrical structure and a glass facade.

Muhammad Ali Center

8.8/10 (295 reviews)

One of the world’s greatest boxers continues providing inspiration beyond the world of sport. Understand this superstar by visiting this center honoring him.

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A wall of wooden baseball bats organized by size and weight.

Louisville Slugger Museum

9.2/10 (2,299 reviews)

Baseball is part of the American fabric. See where one important tool for this sport is produced in the factory that makes ball games possible.

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Golden Statue of David

Find out about the history of Louisville when you spend time at Golden Statue of David. Attend a sporting event or simply enjoy the lively bars while you're in the area.

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Kentucky Museum of Art and Craft

You can spend an afternoon exploring the galleries in Kentucky Museum of Art and Craft during your trip to Louisville. Stroll along the area's riverfront or experience its lively festivals.

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Evan Williams Bourbon Experience

8.6/10 (20 reviews)

You can take time to visit Evan Williams Bourbon Experience during your travels to Louisville. Attend a sporting event or simply enjoy the lively bars while you're in the area.

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SAR Genealogical Research Library: NSSAR Library

You can spend time exploring the galleries in SAR Genealogical Research Library: NSSAR Library in Louisville. Amble around this family-friendly area's riverfront and enjoy its top-notch restaurants.

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Frequently asked questions

What's the area like around 21c Museum Hotel?

21c Museum Hotel is located in a family-friendly area of Louisville known for its stunning river views and great live music scene. If you're looking for a convenient place to stay, take a look at the 292 hotels and other accommodation options you'll find within a mile.

What's the best hotel to stay near 21c Museum Hotel?

Adjacent to 21c Museum Hotel, Galt House Hotel Trademark Collection by Wyndham is one of the top choices for your stay based on our traveller data, and this hotel offers a full-service spa and 4 restaurants. Other good choices within a short distance include Holiday Inn Express & Suites Louisville Downtown by IHG and Omni Louisville Hotel.

How many hotels are there near 21c Museum Hotel?

Expedia has 292 hotels and other accommodation options within a mile from 21c Museum Hotel.

If I need to cancel the hotel reservation for my stay near 21c Museum Hotel, will I receive a refund?

Yes, you'll find most room reservations are refundable if you cancel prior to the accommodation's cancellation deadline, which is often 24 or 48 hours before your check-in date. If you have a non-refundable reservation, you might be able to still cancel and receive a refund within 24 hours of your booking. Add your dates and click on "Search", then use the "fully refundable" filter to get the best deals available near 21c Museum Hotel.

What can I see and do near 21c Museum Hotel?

You might want to spend some time browsing the exhibits at Muhammad Ali Center, Louisville Slugger Museum or Frazier International History Museum. Explore landmarks like Belle of Louisville, Whiskey Row and Big Four Bridge. You can watch performances at Louisville Palace, Derby Dinner Playhouse and Headliners Music Hall if you're interested in local theatre.

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Our top choices for 21c Museum Hotel hotels

1. Hotel Distil, Autograph Collection

2. The Brown Hotel

3. Omni Louisville Hotel

4. Tempo By Hilton Louisville Downtown Nulu

5. DuPont Mansion Bed & Breakfast

6. Stellar Suites

7. Homewood Suites by Hilton Louisville Downtown, KY

8. The Grady

9. Cambria Hotel Louisville Downtown-Whiskey Row

10. 21c Museum Hotel Louisville

11. Hotel Bourré Bonne Louisville, Curio Collection by Hilton

12. Aloft by Marriott Louisville Downtown

13. Moxy Louisville Downtown

14. Towneplace Suites By Marriott Louisville Downtown

15. AC Hotel Louisville Downtown

16. Hotel Genevieve part of JdV by Hyatt

17. Galt House Hotel Trademark Collection by Wyndham

18. Central Park Bed & Breakfast

19. Embassy Suites Louisville Downtown

20. Hyatt Regency Louisville

Compare popular hotels close to 21c Museum Hotel

Top 21c Museum Hotel Hotel Reviews

Galt House Hotel Trademark Collection by Wyndham

Towneplace Suites By Marriott Louisville Downtown

Radisson Hotel Louisville North

The Grady

Holiday Inn Express & Suites Louisville Downtown by IHG

Hyatt Regency Louisville

Embassy Suites Louisville Downtown

Louisville Marriott Downtown

Moxy Louisville Downtown

Other attractions near 21c Museum Hotel

Louisville Science Center

Kentucky Center for the Performing Arts

Muhammad Ali Center

Louisville Slugger Museum

Golden Statue of David

Kentucky Museum of Art and Craft

Evan Williams Bourbon Experience

SAR Genealogical Research Library: NSSAR Library

Frequently asked questions

Explore a world of travel with Expedia