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Check prices for these dates

Tonight
14 Mar - 15 Mar
Tomorrow
15 Mar - 16 Mar
Next weekend
20 Mar - 22 Mar
In two weeks
27 Mar - 29 Mar

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Our top choices for 21c Museum Hotel hotels

Terrace/patio

Homewood Suites by Hilton Louisville Downtown, KY

Homewood Suites by Hilton Louisville Downtown, KY
3.0 star property
Downtown Louisville, 0.1 km from 21c Museum Hotel
9.4 out of 10, Exceptional, (1,001 reviews)
"Great staff nice hotel "
United States
david
The price is ₹9,896
₹11,643 total
includes taxes & fees
5 Apr - 6 Apr
Homewood Suites by Hilton Louisville Downtown, KY
Terrace/patio

Hotel Distil, Autograph Collection

Hotel Distil, Autograph Collection
4.0 star property
Downtown Louisville, 0.8 km from 21c Museum Hotel
9.6 out of 10, Exceptional, (456 reviews)
"Great hotel & location"
United States
Ana
The price is ₹16,192
₹19,052 total
includes taxes & fees
5 Apr - 6 Apr
Hotel Distil, Autograph Collection
Lobby

The Grady

The Grady
4.0 star property
Downtown Louisville, 0.1 km from 21c Museum Hotel
9.4 out of 10, Exceptional, (1,000 reviews)
"The decor was so charming and the Wild Swann was fabulous! "
United States
Kelly
The price is ₹23,882
₹28,100 total
includes taxes & fees
27 Mar - 28 Mar
The Grady
Room (Asleep in the Cyclone) | Premium bedding, down duvets, minibar, in-room safe

21c Museum Hotel Louisville

21c Museum Hotel Louisville
4.5 star property
Downtown Louisville, < 0.1 km from 21c Museum Hotel
9.4 out of 10, Exceptional, (1,002 reviews)
"Lovely hotel. Would stay there again."
United States
Kristin Woxland
The price is ₹16,503
₹19,879 total
includes taxes & fees
15 Mar - 16 Mar
21c Museum Hotel Louisville
Front of property

DuPont Mansion Bed & Breakfast

DuPont Mansion Bed & Breakfast
3.0 star property
Old Louisville, 2.8 km from 21c Museum Hotel
9.8 out of 10, Exceptional, (108 reviews)
"Breakfast was wonderful, great place to stay!"
United States
Janie
The price is ₹11,754
₹13,642 total
includes taxes & fees
15 Mar - 16 Mar
DuPont Mansion Bed & Breakfast
Interior

The Brown Hotel

The Brown Hotel
4.5 star property
Downtown Louisville, 1.2 km from 21c Museum Hotel
9.4 out of 10, Exceptional, (1,182 reviews)
"Awesome staff, beautiful hotel, great food and bar"
United States
Jason
The Brown Hotel
Dining

Cambria Hotel Louisville Downtown-Whiskey Row

Cambria Hotel Louisville Downtown-Whiskey Row
3.0 star property
Downtown Louisville, 1.2 km from 21c Museum Hotel
9.4 out of 10, Exceptional, (1,004 reviews)
"Location is convenient, able to walk to many restaurants and attractions. Staff is great."
United States
Luigi
The price is ₹8,802
₹10,357 total
includes taxes & fees
5 Apr - 6 Apr
Cambria Hotel Louisville Downtown-Whiskey Row
Property amenity

Towneplace Suites By Marriott Louisville Downtown

Towneplace Suites By Marriott Louisville Downtown
3.0 star property
Downtown Louisville, 0.3 km from 21c Museum Hotel
9.2 out of 10, Wonderful, (561 reviews)
"Always enjoy our stays here, staff are so friendly and helpful!"
United States
Debra
The price is ₹9,338
₹10,987 total
includes taxes & fees
29 Mar - 30 Mar
Towneplace Suites By Marriott Louisville Downtown
Lounge

Stellar Suites

Stellar Suites
4.5 star property
East Market District, 2.2 km from 21c Museum Hotel
9.6 out of 10, Exceptional, (126 reviews)
"Easy check in and check out process and very convenient location."
United States
Richard
The price is ₹10,256
₹16,733 total
includes taxes & fees
30 Mar - 31 Mar
Stellar Suites
2 restaurants, breakfast served

Tempo By Hilton Louisville Downtown Nulu

Tempo By Hilton Louisville Downtown Nulu
3.5 star property
Phoenix Hill, 2 km from 21c Museum Hotel
9.4 out of 10, Exceptional, (944 reviews)
"Nice place with friendly staff."
United States
Steve
The price is ₹8,313
₹9,781 total
includes taxes & fees
4 Apr - 5 Apr
Tempo By Hilton Louisville Downtown Nulu
3 bars/lounges, cocktail bar, lobby lounge

Omni Louisville Hotel

Omni Louisville Hotel
4.0 star property
Downtown Louisville, 0.8 km from 21c Museum Hotel
9.2 out of 10, Wonderful, (1,794 reviews)
"Beautiful hotel perfectly located within downtown Louisville. The restaurant, bar and amenities offered are second to none. "
United States
Michael
The price is ₹16,939
₹19,931 total
includes taxes & fees
29 Mar - 30 Mar
Omni Louisville Hotel
Interior entrance

Moxy Louisville Downtown

Moxy Louisville Downtown
3.5 star property
Downtown Louisville, 0.9 km from 21c Museum Hotel
9.2 out of 10, Wonderful, (722 reviews)
"Awesome location and the staff was super friendly"
United States
Kelly
The price is ₹8,229
₹9,682 total
includes taxes & fees
5 Apr - 6 Apr
Moxy Louisville Downtown
4 restaurants, breakfast, lunch, dinner served; American cuisine

Galt House Hotel Trademark Collection by Wyndham

Galt House Hotel Trademark Collection by Wyndham
4.0 star property
Downtown Louisville, 0.5 km from 21c Museum Hotel
9.0 out of 10, Wonderful, (4,086 reviews)
"Room was great, hotel was clean"
United States
Jordan
The price is ₹11,676
₹13,738 total
includes taxes & fees
30 Mar - 31 Mar
Galt House Hotel Trademark Collection by Wyndham
Exterior

Hotel Bourré Bonne Louisville, Curio Collection by Hilton

Hotel Bourré Bonne Louisville, Curio Collection by Hilton
4.0 star property
Downtown Louisville, 0.8 km from 21c Museum Hotel
9.2 out of 10, Wonderful, (81 reviews)
"We enjoyed our stay. Staff was amazing! Room was wonderful."
United States
David
The price is ₹13,282
₹15,627 total
includes taxes & fees
3 Apr - 4 Apr
Hotel Bourré Bonne Louisville, Curio Collection by Hilton
27-inch Smart TV with satellite channels

The Duke Hotel

The Duke Hotel
2.0 star property
East Market District, 2.1 km from 21c Museum Hotel
9.4 out of 10, Exceptional, (6 reviews)
"Clean, lovely stay. "
United States
Hannah
The price is ₹6,565
₹12,985 total
includes taxes & fees
16 Mar - 17 Mar
The Duke Hotel
Lobby lounge

AC Hotel Louisville Downtown

AC Hotel Louisville Downtown
3.5 star property
East Market District, 2 km from 21c Museum Hotel
9.2 out of 10, Wonderful, (629 reviews)
"Nice hotel, super overpriced"
United States
Kevin
The price is ₹9,832
₹11,568 total
includes taxes & fees
3 Apr - 4 Apr
AC Hotel Louisville Downtown
Exterior

Louisville Marriott Downtown

Louisville Marriott Downtown
4.0 star property
Downtown Louisville, 0.7 km from 21c Museum Hotel
9.0 out of 10, Wonderful, (1,003 reviews)
"We had a great stay"
United States
Jacob
The price is ₹15,505
₹18,244 total
includes taxes & fees
5 Apr - 6 Apr
Louisville Marriott Downtown
Restaurant

Aloft Louisville Downtown

Aloft Louisville Downtown
3.0 star property
Downtown Louisville, 0.9 km from 21c Museum Hotel
9.0 out of 10, Wonderful, (1,003 reviews)
"Easy and direct route to our event for the evening ..."
United States
MDC
The price is ₹10,283
₹12,099 total
includes taxes & fees
5 Apr - 6 Apr
Aloft Louisville Downtown
Reception

Embassy Suites Louisville Downtown

Embassy Suites Louisville Downtown
4.0 star property
Downtown Louisville, 0.8 km from 21c Museum Hotel
9.0 out of 10, Wonderful, (1,163 reviews)
"Great location "
United States
Robert
The price is ₹10,608
₹12,481 total
includes taxes & fees
5 Apr - 6 Apr
Embassy Suites Louisville Downtown
View from property

TownePlace Suites by Marriott Louisville North

TownePlace Suites by Marriott Louisville North
3.0 star property
2.2 km from 21c Museum Hotel
9.2 out of 10, Wonderful, (663 reviews)
"Large, clean rooms and staff was exceptional!"
United States
ANGIE
The price is ₹11,557
₹13,060 total
includes taxes & fees
3 Apr - 4 Apr
TownePlace Suites by Marriott Louisville North
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top 21c Museum Hotel Hotel Reviews

Cambria Hotel Louisville Downtown-Whiskey Row

Cambria Hotel Louisville Downtown-Whiskey Row

10/10 Excellent
"Very clean and well put together. Close to shops, food options, and the Yum Center."
Dylan 1-night trip
Posted 4 hours ago
Cambria Hotel Louisville Downtown-Whiskey Row

Hotels near other 21c Museum Hotel attractions

Louisville Science Center

Louisville Science Center

Science is all around us, inescapable. Understand important elements of our world with a visit to this science center for all ages.
See properties
Kentucky Center for the Performing Arts

Kentucky Center for the Performing Arts

Enjoy a pleasant night at the opera or attend a concert, live dance or stage production at this glass-fronted venue in downtown Louisville.
See properties

Frequently asked questions

What's the area like around 21c Museum Hotel?
21c Museum Hotel is located in a family-friendly area of Louisville known for its stunning river views and great live music scene. If you're looking for a convenient place to stay, take a look at the 250 hotels and other accommodation options you'll find within a mile.
What's the best hotel to stay near 21c Museum Hotel?
Adjacent to 21c Museum Hotel, Galt House Hotel Trademark Collection by Wyndham is one of the top choices for your stay based on our traveller data, and this hotel offers a full-service spa and 4 restaurants. Other good choices within a short distance include Omni Louisville Hotel and Holiday Inn Express & Suites Louisville Downtown by IHG.
How many hotels are there near 21c Museum Hotel?
Expedia has 250 hotels and other accommodation options within a mile from 21c Museum Hotel.
If I need to cancel the hotel reservation for my stay near 21c Museum Hotel, will I receive a refund?
Yes, you'll find most room reservations are refundable if you cancel prior to the accommodation's cancellation deadline, which is often 24 or 48 hours before your check-in date. If you have a non-refundable reservation, you might be able to still cancel and receive a refund within 24 hours of your booking. Add your dates and click on "Search", then use the "fully refundable" filter to get the best deals available near 21c Museum Hotel.
What can I see and do near 21c Museum Hotel?
You might want to spend some time browsing the exhibits at Louisville Science Center, Muhammad Ali Center or Louisville Slugger Museum. Explore landmarks like Belle of Louisville, Whiskey Row and Thomas Edison House. You can watch performances at Louisville Palace, Derby Dinner Playhouse and Headliners Music Hall if you're interested in local theatre.

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