Search Hotels Near 21c Museum Hotel, Louisville

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12 Dec - 13 Dec
Tomorrow
13 Dec - 14 Dec
This weekend
12 Dec - 14 Dec
Next weekend
19 Dec - 21 Dec

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Our top choices for 21c Museum Hotel hotels

Terrace/patio
Hotel Distil, Autograph Collection

Hotel Distil, Autograph Collection

Hotel Distil, Autograph Collection
4.0 star property
Downtown Louisville, 0.9 km from 21c Museum Hotel
9.6 out of 10, Exceptional, (428)
"Great location. Great restraunt, great staff. Pleasurable experience!"
United States
Harrison
The price is ₹15,755
₹18,537 total
includes taxes & fees
27 Dec - 28 Dec
Hotel Distil, Autograph Collection
Lobby
The Grady

The Grady

The Grady
4.0 star property
Downtown Louisville, 0.1 km from 21c Museum Hotel
9.4 out of 10, Exceptional, (1000)
"The location was outstanding and atmosphere was very nice."
United States
Malcolm
The price is ₹13,036
₹15,338 total
includes taxes & fees
21 Dec - 22 Dec
The Grady
Interior entrance
Market Street Inn

Market Street Inn

Market Street Inn
3.5 star property
2.1 km from 21c Museum Hotel
9.8 out of 10, Exceptional, (120)
"I enjoyed my stay, however the breakfast portion was very small even for a petite person like myself, I was still very hungry after breakfast. There was a cleaning issue with the bathroom that was overlooked by the cleaning staff that I alerted the owners to that will hopefully be fixed for future visitors. The house is great and very clean overall. The owners are very nice."
United States
Megan
The price is ₹16,666
₹18,834 total
includes taxes & fees
14 Dec - 15 Dec
Market Street Inn
Dining
Cambria Hotel Louisville Downtown-Whiskey Row

Cambria Hotel Louisville Downtown-Whiskey Row

Cambria Hotel Louisville Downtown-Whiskey Row
3.0 star property
Downtown Louisville, 1.2 km from 21c Museum Hotel
9.4 out of 10, Exceptional, (1001)
"All the staff we met were really nice! The rooms are clean and spacious."
United States
Kelly Anne
The price is ₹7,873
₹9,263 total
includes taxes & fees
25 Dec - 26 Dec
Cambria Hotel Louisville Downtown-Whiskey Row
Front of property
DuPont Mansion Bed & Breakfast

DuPont Mansion Bed & Breakfast

DuPont Mansion Bed & Breakfast
3.0 star property
Old Louisville, 2.8 km from 21c Museum Hotel
9.8 out of 10, Exceptional, (97)
"Breakfast was wonderful, great place to stay!"
United States
Janie
The price is ₹11,822
₹13,721 total
includes taxes & fees
23 Dec - 24 Dec
DuPont Mansion Bed & Breakfast
Terrace/patio
Homewood Suites by Hilton Louisville Downtown, KY

Homewood Suites by Hilton Louisville Downtown, KY

Homewood Suites by Hilton Louisville Downtown, KY
3.0 star property
Downtown Louisville, 0.1 km from 21c Museum Hotel
9.2 out of 10, Wonderful, (1000)
"The room was wonderful and the staff exceptional."
United States
Daniel
The price is ₹8,996
₹10,585 total
includes taxes & fees
9 Jan - 10 Jan 2026
Homewood Suites by Hilton Louisville Downtown, KY
Lobby
The Brown Hotel

The Brown Hotel

The Brown Hotel
4.5 star property
Downtown Louisville, 1.2 km from 21c Museum Hotel
9.4 out of 10, Exceptional, (1150)
"I loved everything about this place"
United States
Steven
The Brown Hotel
Lounge
Stellar Suites

Stellar Suites

Stellar Suites
4.5 star property
East Market District, 2.2 km from 21c Museum Hotel
9.6 out of 10, Exceptional, (117)
"Clean and great location "
United States
Greg
The price is ₹9,553
₹15,788 total
includes taxes & fees
5 Jan - 6 Jan 2026
Stellar Suites
Property amenity
Towneplace Suites By Marriott Louisville Downtown

Towneplace Suites By Marriott Louisville Downtown

Towneplace Suites By Marriott Louisville Downtown
3.0 star property
Downtown Louisville, 0.3 km from 21c Museum Hotel
9.2 out of 10, Wonderful, (508)
"Great rooms "
United States
Ayden
The price is ₹8,726
₹10,267 total
includes taxes & fees
5 Jan - 6 Jan 2026
Towneplace Suites By Marriott Louisville Downtown
Front of property
21c Museum Hotel Louisville

21c Museum Hotel Louisville

21c Museum Hotel Louisville
4.5 star property
Downtown Louisville, < 0.1 km from 21c Museum Hotel
9.2 out of 10, Wonderful, (1002)
"Staff was very kind, the art was fantastic, location was perfect to explore Whiskey Row, and we had a gorgeous room. Loved our time away there!"
United States
Tammy
The price is ₹12,505
₹15,164 total
includes taxes & fees
1 Jan - 2 Jan 2026
21c Museum Hotel Louisville
3 bars/lounges, cocktail bar, lobby lounge
Omni Louisville Hotel

Omni Louisville Hotel

Omni Louisville Hotel
4.0 star property
Downtown Louisville, 0.8 km from 21c Museum Hotel
9.2 out of 10, Wonderful, (1725)
"This is a beautiful hotel in a great location. Very kind staff and helpful with directions."
United States
Bonnie
The price is ₹15,042
₹17,699 total
includes taxes & fees
1 Jan - 2 Jan 2026
Omni Louisville Hotel
Interior entrance
Moxy Louisville Downtown

Moxy Louisville Downtown

Moxy Louisville Downtown
3.5 star property
Downtown Louisville, 0.9 km from 21c Museum Hotel
9.2 out of 10, Wonderful, (696)
"Awesome location and the staff was super friendly"
United States
Kelly
The price is ₹9,356
₹11,008 total
includes taxes & fees
22 Dec - 23 Dec
Moxy Louisville Downtown
2 restaurants, breakfast served
Tempo By Hilton Louisville Downtown Nulu

Tempo By Hilton Louisville Downtown Nulu

Tempo By Hilton Louisville Downtown Nulu
3.5 star property
Phoenix Hill, 2 km from 21c Museum Hotel
9.4 out of 10, Exceptional, (818)
"Love the hotel and will always stay there when visiting "
United States
Jeremy
The price is ₹8,603
₹10,122 total
includes taxes & fees
27 Dec - 28 Dec
Tempo By Hilton Louisville Downtown Nulu
4 restaurants, breakfast, lunch, dinner served; American cuisine
Galt House Hotel Trademark Collection by Wyndham

Galt House Hotel Trademark Collection by Wyndham

Galt House Hotel Trademark Collection by Wyndham
4.0 star property
Downtown Louisville, 0.5 km from 21c Museum Hotel
9.0 out of 10, Wonderful, (3846)
"Beautiful room and great hospitality. "
United States
Chase
The price is ₹11,992
₹14,110 total
includes taxes & fees
21 Dec - 22 Dec
Galt House Hotel Trademark Collection by Wyndham
Reception
Embassy Suites Louisville Downtown

Embassy Suites Louisville Downtown

Embassy Suites Louisville Downtown
4.0 star property
Downtown Louisville, 0.8 km from 21c Museum Hotel
9.0 out of 10, Wonderful, (1107)
"Staff was courteous, hotel was beautiful and clean, and breakfast was amazing!"
United States
Shunskis
The price is ₹10,004
₹11,771 total
includes taxes & fees
29 Dec - 30 Dec
Embassy Suites Louisville Downtown
Restaurant
Aloft Louisville Downtown

Aloft Louisville Downtown

Aloft Louisville Downtown
3.0 star property
Downtown Louisville, 0.9 km from 21c Museum Hotel
9.0 out of 10, Wonderful, (1002)
"Good"
United States
Les
The price is ₹8,743
₹10,287 total
includes taxes & fees
19 Dec - 20 Dec
Aloft Louisville Downtown
Exterior detail
Central Park Bed & Breakfast

Central Park Bed & Breakfast

Central Park Bed & Breakfast
4.0 star property
Old Louisville, 2.9 km from 21c Museum Hotel
9.4 out of 10, Exceptional, (57)
"Our stay here was excellent in every way! The owners were very sweet and went out of their way to assist us in every way, the rooms were very cozy, and the breakfasts were fantastic. This is the best B&B we've ever stayed."
United States
John
The price is ₹12,077
₹14,017 total
includes taxes & fees
14 Dec - 15 Dec
Central Park Bed & Breakfast
Lobby lounge
AC Hotel Louisville Downtown

AC Hotel Louisville Downtown

AC Hotel Louisville Downtown
3.5 star property
East Market District, 2 km from 21c Museum Hotel
9.2 out of 10, Wonderful, (598)
"Loved the Hotel and area around the Hotel. Great shopping and restaurants"
United States
Melissa
The price is ₹9,678
₹11,388 total
includes taxes & fees
19 Dec - 20 Dec
AC Hotel Louisville Downtown
Exterior
Louisville Marriott Downtown

Louisville Marriott Downtown

Louisville Marriott Downtown
4.0 star property
Downtown Louisville, 0.7 km from 21c Museum Hotel
9.0 out of 10, Wonderful, (1000)
"Very nice hotel. Great stay!"
United States
Brad
The price is ₹15,396
₹18,115 total
includes taxes & fees
22 Dec - 23 Dec
Louisville Marriott Downtown
Exterior
Holiday Inn Express & Suites Louisville Downtown by IHG

Holiday Inn Express & Suites Louisville Downtown by IHG

Holiday Inn Express & Suites Louisville Downtown by IHG
2.5 star property
Downtown Louisville, 0.2 km from 21c Museum Hotel
8.8 out of 10, Excellent, (1650)
"Great place I would definitely book again"
United States
Lisa
The price is ₹7,377
₹8,680 total
includes taxes & fees
23 Dec - 24 Dec
Holiday Inn Express & Suites Louisville Downtown by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Top 21c Museum Hotel Hotel Reviews

Radisson Hotel Louisville North

Radisson Hotel Louisville North

10/10 Excellent
"It was a great stay my only complaint is they have the fans on in the pool area and it makes it really cold when you get out of the pool other then that amazing place"
Miranda 4-night trip
Posted 2 days ago
Radisson Hotel Louisville North

Hotels near other 21c Museum Hotel attractions

Louisville Science Center

Louisville Science Center

Science is all around us, inescapable. Understand important elements of our world with a visit to this science center for all ages.
See properties
Kentucky Center for the Performing Arts

Kentucky Center for the Performing Arts

Enjoy a pleasant night at the opera or attend a concert, live dance or stage production at this glass-fronted venue in downtown Louisville.
See properties

Frequently asked questions

What's the area like around 21c Museum Hotel?
21c Museum Hotel is located in a family-friendly area of Louisville known for its stunning river views and great live music scene. If you're looking for a convenient place to stay, take a look at the 291 hotels and other accommodation options you'll find within a mile.
What's the best hotel to stay near 21c Museum Hotel?
Adjacent to 21c Museum Hotel, Galt House Hotel Trademark Collection by Wyndham is one of the top choices for your stay based on our traveller data, and this hotel offers a full-service spa and 4 restaurants. Other good choices within a short distance include Omni Louisville Hotel and Holiday Inn Express & Suites Louisville Downtown by IHG.
How many hotels are there near 21c Museum Hotel?
Expedia has 291 hotels and other accommodation options within a mile from 21c Museum Hotel.
If I need to cancel the hotel reservation for my stay near 21c Museum Hotel, will I receive a refund?
Yes, you'll find most room reservations are refundable if you cancel prior to the accommodation's cancellation deadline, which is often 24 or 48 hours before your check-in date. If you have a non-refundable reservation, you might be able to still cancel and receive a refund within 24 hours of your booking. Add your dates and click on "Search", then use the "fully refundable" filter to get the best deals available near 21c Museum Hotel.
What can I see and do near 21c Museum Hotel?
You might want to spend some time browsing the exhibits at Louisville Science Center, Muhammad Ali Center or Louisville Slugger Museum. Explore landmarks like Belle of Louisville, Whiskey Row and Big Four Bridge. You can watch performances at Kentucky Center for the Performing Arts, Louisville Palace and Derby Dinner Playhouse if you're interested in local theatre.

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