The Best Hotels Closest to Louisville Science Center in Louisville - 2026 Updated Prices

Q: What's the area like around Louisville Science Center?

Louisville Science Center is located in an area of Louisville known for its stunning river views, sporting events and great live music scene. If you're looking for a convenient place to stay, take a look at the 250 hotels and other accommodation options you'll find within a mile.

Q: Where is the best place to stay near Louisville Science Center?

Adjacent to Louisville Science Center, Holiday Inn Express & Suites Louisville Downtown by IHG is one of the top choices for your stay based on our traveller data, and this hotel offers free breakfast and a 24-hour fitness centre. Other good choices within a short distance include Galt House Hotel Trademark Collection by Wyndham and Omni Louisville Hotel .

Q: How many hotels can I expect to find close to Louisville Science Center?

Expedia has 250 hotels and other accommodation options within a mile from Louisville Science Center.

Q: If I need to cancel the hotel reservation for my stay near Louisville Science Center, will I receive a refund?

Yes! Most hotel room reservations are fully refundable as long as you cancel before the hotel’s cancellation deadline, which is usually within 24-48 hours of check in. If you booked a non-refundable reservation, you might be able to still cancel and get a refund within a 24-hour period of booking. Add dates, click "Search", then use the filter option "fully refundable" to get the top deals on offer near Louisville Science Center.

Q: What can I see and do near Louisville Science Center?

21c Museum Hotel, Louisville Slugger Museum and Muhammad Ali Center feature a variety of fascinating exhibits to see while you're in town. Explore landmarks like Belle of Louisville, Whiskey Row and Big Four Bridge. You can catch a show at Louisville Palace, Derby Dinner Playhouse and Headliners Music Hall.

Our top choices for Louisville Science Center hotels

1. Louisville Bourbon Inn

Old Louisville, 2.9 km from Louisville Science Center

Roy

₹34,747 total

includes taxes & fees

28 Jul - 29 Jul

2. Market Street Inn

2.1 km from Louisville Science Center

Anissa

₹18,194 total

includes taxes & fees

28 Jul - 29 Jul

3. Stellar Suites

East Market District, 2.2 km from Louisville Science Center

Brad

₹16,321 total

includes taxes & fees

3 Aug - 4 Aug

4. Hotel Distil, Autograph Collection

Downtown Louisville, 0.9 km from Louisville Science Center

Jasmine

₹24,898 total

includes taxes & fees

9 Aug - 10 Aug

5. DuPont Mansion Bed & Breakfast

Old Louisville, 2.8 km from Louisville Science Center

Casey

₹19,605 total

includes taxes & fees

5 Aug - 6 Aug

6. Homewood Suites by Hilton Louisville Downtown, KY

Downtown Louisville, 0.2 km from Louisville Science Center

Torrence

₹13,882 total

includes taxes & fees

23 Aug - 24 Aug

7. The Brown Hotel

Downtown Louisville, 1.2 km from Louisville Science Center

Anthony

₹16,728 total

includes taxes & fees

28 Jul - 29 Jul

2 restaurants; breakfast and dinner served

8. Tempo By Hilton Louisville Downtown Nulu

Phoenix Hill, 2.1 km from Louisville Science Center

Rodney

₹13,882 total

includes taxes & fees

9 Aug - 10 Aug

3 bars/lounges, cocktail bar, lobby lounge

9. Omni Louisville Hotel

Downtown Louisville, 0.8 km from Louisville Science Center

Brittany

₹18,089 total

includes taxes & fees

2 Aug - 3 Aug

10. 21c Museum Hotel Louisville

Downtown Louisville, < 0.1 km from Louisville Science Center

nicolle

₹17,770 total

includes taxes & fees

24 Aug - 25 Aug

11. The Grady

Downtown Louisville, 0.2 km from Louisville Science Center

Jennifer

₹18,248 total

includes taxes & fees

19 Aug - 20 Aug

12. Hotel Bourré Bonne Louisville, Curio Collection by Hilton

Downtown Louisville, 0.8 km from Louisville Science Center

Kristen

₹19,845 total

includes taxes & fees

2 Aug - 3 Aug

13. Towneplace Suites By Marriott Louisville Downtown

Downtown Louisville, 0.3 km from Louisville Science Center

Michael

₹11,930 total

includes taxes & fees

14 Aug - 15 Aug

14. Cambria Hotel Louisville Downtown-Whiskey Row

Downtown Louisville, 1.2 km from Louisville Science Center

Amy

₹13,102 total

includes taxes & fees

2 Aug - 3 Aug

15. Hotel Genevieve part of JdV by Hyatt

East Market District, 2.1 km from Louisville Science Center

Christina

₹15,339 total

includes taxes & fees

3 Aug - 4 Aug

16. AC Hotel Louisville Downtown

East Market District, 2.1 km from Louisville Science Center

David

₹13,820 total

includes taxes & fees

31 Jul - 1 Aug

17. Moxy Louisville Downtown

Downtown Louisville, 0.9 km from Louisville Science Center

Adam

₹11,817 total

includes taxes & fees

2 Aug - 3 Aug

18. Central Park Bed & Breakfast

Old Louisville, 3 km from Louisville Science Center

Candace Faye

₹16,785 total

includes taxes & fees

28 Jul - 29 Jul

4 restaurants; breakfast, lunch and dinner served

19. Galt House Hotel Trademark Collection by Wyndham

Downtown Louisville, 0.5 km from Louisville Science Center

Kriste

₹18,035 total

includes taxes & fees

1 Aug - 2 Aug

20. Embassy Suites Louisville Downtown

Downtown Louisville, 0.8 km from Louisville Science Center

Mark

₹15,575 total

includes taxes & fees

16 Aug - 17 Aug

View all properties

Compare popular hotels close to Louisville Science Center

Property	Property class	Guest rating
Louisville Bourbon Inn	5.0 star property	10.0 Exceptional 24 reviews	View
Market Street Inn	3.5 star property	9.8 Exceptional 122 reviews	View
Stellar Suites	4.5 star property	9.6 Exceptional 143 reviews	View
Hotel Distil, Autograph Collection	4.0 star property	9.6 Exceptional 485 reviews	View
DuPont Mansion Bed & Breakfast	2.0 star property	9.6 Exceptional 142 reviews	View

Top Louisville Science Center Hotel Reviews

Homewood Suites by Hilton Louisville Downtown, KY

10/10 Excellent

"Great staff. Good breakfast"

Cambria Hotel Louisville Downtown-Whiskey Row

8/10 Good

"My family and I were in town visiting. The hotel was nice and conveniently located to our destination. The staff were both courteous and professional. Our room was clean and the beds were comfortable. We did get a noise complaint, but I did have a 4 year old who’s on the spectrum and of course he was bouncing around a little. I’ll keep in mind for future references to ask to be roomed on the lowest floor to prevent any noise complaints when traveling with younger children. The only downside was the parking. Very small parking garage with limited space, so we had to park on the street. Other than the parking and noise complaint, our overall stay was pretty good."

Hotels near other Louisville Science Center attractions

A wall of wooden baseball bats organized by size and weight.

Louisville Slugger Museum

9.2/10 (2,299 reviews)

Baseball is part of the American fabric. See where one important tool for this sport is produced in the factory that makes ball games possible.

See properties

Frequently asked questions

What's the area like around Louisville Science Center?

Louisville Science Center is located in an area of Louisville known for its stunning river views, sporting events and great live music scene. If you're looking for a convenient place to stay, take a look at the 250 hotels and other accommodation options you'll find within a mile.

Where is the best place to stay near Louisville Science Center?

Adjacent to Louisville Science Center, Holiday Inn Express & Suites Louisville Downtown by IHG is one of the top choices for your stay based on our traveller data, and this hotel offers free breakfast and a 24-hour fitness centre. Other good choices within a short distance include Galt House Hotel Trademark Collection by Wyndham and Omni Louisville Hotel.

How many hotels can I expect to find close to Louisville Science Center?

Expedia has 250 hotels and other accommodation options within a mile from Louisville Science Center.

If I need to cancel the hotel reservation for my stay near Louisville Science Center, will I receive a refund?

Yes! Most hotel room reservations are fully refundable as long as you cancel before the hotel's cancellation deadline, which is usually within 24-48 hours of check in. If you booked a non-refundable reservation, you might be able to still cancel and get a refund within a 24-hour period of booking. Add dates, click "Search", then use the filter option "fully refundable" to get the top deals on offer near Louisville Science Center.

What can I see and do near Louisville Science Center?

21c Museum Hotel, Louisville Slugger Museum and Muhammad Ali Center feature a variety of fascinating exhibits to see while you're in town. Explore landmarks like Belle of Louisville, Whiskey Row and Big Four Bridge. You can catch a show at Louisville Palace, Derby Dinner Playhouse and Headliners Music Hall.

Explore a world of travel with Expedia

Flights to Louisville

Search Hotels Near Louisville Science Center, Louisville

Change your mind

Treat yourself

Be picky

Check prices for these dates

Filter by

Our top choices for Louisville Science Center hotels

1. Louisville Bourbon Inn

2. Market Street Inn

3. Stellar Suites

4. Hotel Distil, Autograph Collection

5. DuPont Mansion Bed & Breakfast

6. Homewood Suites by Hilton Louisville Downtown, KY

7. The Brown Hotel

8. Tempo By Hilton Louisville Downtown Nulu

9. Omni Louisville Hotel

10. 21c Museum Hotel Louisville

11. The Grady

12. Hotel Bourré Bonne Louisville, Curio Collection by Hilton

13. Towneplace Suites By Marriott Louisville Downtown

14. Cambria Hotel Louisville Downtown-Whiskey Row

15. Hotel Genevieve part of JdV by Hyatt

16. AC Hotel Louisville Downtown

17. Moxy Louisville Downtown

18. Central Park Bed & Breakfast

19. Galt House Hotel Trademark Collection by Wyndham

20. Embassy Suites Louisville Downtown

Compare popular hotels close to Louisville Science Center

Top Louisville Science Center Hotel Reviews

Homewood Suites by Hilton Louisville Downtown, KY

Hotels near other Louisville Science Center attractions

Louisville Slugger Museum

Frequently asked questions

Explore a world of travel with Expedia