Popular places to visit
St. Louis Union Station
You can learn more about the history of St. Louis during your trip to a well-known site such as St. Louis Union Station. Experience the area's great live music or attend a baseball game.
Gateway Arch
Visit the Museum of Westward Expansion, then ascend to the top of the tallest man-made monument in the US for breathtaking views of St. Louis.
St. Louis Zoo
In the middle of St. Louis, meet the exotic and endangered animals that live in meticulously recreated ecosystems from all over the world.
Busch Stadium
Catch an event at Busch Stadium during your trip to St. Louis. Experience the area's great live music or attend a baseball game.
City Museum
A rooftop Ferris wheel, an indoor tree house and a life-size, walk-through model of a whale; just some of the exhibits in this one-of-a-kind children's museum.
Forest Park
Nature, history and cultural institutions come together in one of the United States’ largest urban parks, which buzzes with St. Louis’ dynamic community spirit.
Top hotels in Clayton
Clayton Plaza Hotel & Extended Stay
We were in St Louis for a volleyball game at UMSL. Perfect location for getting to UMSL and places to eat. Hotel staff were amazing! Everyone so friendly. I felt safe and the room was very clean. Breakfast in the morning was well above a traditional hotel breakfast. We will stay here again.
Reviewed on 5 Dec 2025
AC Hotel St. Louis Clayton
The staff were very helpful while there! I recommend doing valet instead of self parking so you wouldn’t have to go through any hassle with finding a parking space but overall my stay was great. The bed was really comfy. I would definitely stay there again when visiting St Louis.
Reviewed on 25 Nov 2025
Hampton Inn & Suites Clayton/St. Louis-Galleria Area
Onsite parking was great!
Reviewed on 1 Dec 2025
Le Méridien St. Louis Clayton
Small rooms but beautiful lobby.
Reviewed on 27 Oct 2025
Hyatt Regency St. Louis at The Arch
The room was very nice and clean, but the lights went out and there was no hot water to bathe; on the 29&30. Also, I was not told about the 75 dollars incidental fee per night.which caused my family to spend money not in our budget for our Thanksgiving Trip.
Reviewed on 4 Dec 2025
Magnolia Hotel St. Louis, a Tribute Portfolio Hotel
Beautiful hotel. Wonderful atmosphere. Clean rooms. Would definitely stay there again.
Reviewed on 4 Dec 2025
Other neighbourhoods around Clayton
Dogtown
When in Dogtown, you can plan a visit to St. Louis Zoo and St. Louis Art Museum, some noteworthy sights in the nearby area.
University City
Noted for its shopping and restaurants, there's plenty to explore in University City. Top attractions like St. Louis Black Repertory Company and Center of Creative Arts are major draws, and you can hop on the metro at Forsyth Station or U City Big Bend Station to see more of the city.
Ladue
Ladue is well liked for its restaurants and churches. If you're hoping to see more of the larger area, Saint Louis Galleria Mall and Bella Vita Wines are some interesting sights nearby to check out.
The Hill
While The Hill isn't home to many top sights, St. Louis Science Center and Missouri Botanical Gardens and Arboretum are some notable places to visit nearby.
Central West End
If you're looking for things to see and do in Central West End, ample dining options and lush forests are highlights. You might also check out World Chess Hall of Fame while you're visiting, and jump aboard the metro at Central West End Station to get around town.
The Grove
While there might not be top attractions in The Grove, you can explore the larger area and discover places like St. Louis Science Center and Missouri Botanical Gardens and Arboretum.
Clayton Travel Guide
- Places of interest
- Choose Your Clayton Hotel Style
- Hotels in top St. Louis neighborhoods
- Search Clayton Hotel Brands
- Chapel of St. Timothy And St. Titus
- St. Louis Zoo
- Busch Stadium
- Dome at America’s Center
- Barnes Jewish Hospital
- City Museum
- Forest Park
- Mississippi River
- Hollywood Casino Amphitheatre
- St. Louis University
- Fox Theater
- Horseshoe St. Louis Casino
- Anheuser-Busch Brewery
- Missouri Botanical Gardens and Arboretum
- Saint Louis Galleria Mall
- Magic House - St. Louis Children's Museum
- St. Louis Premium Outlets
- St. Louis Science Center
- Grant's Farm
- Lindenwood University
