A blue bridge with pedestrians, a city skyline with a prominent building labeled 'PNC', and modern architecture.

Search Boutique Hotels in Southwest Ohio

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check availability on Southwest Ohio Boutique Hotels

Tonight
29 Sept - 30 Sept
Tomorrow
30 Sept - 1 Oct
This weekend
2 Oct - 4 Oct
Next weekend
9 Oct - 11 Oct

Our top choices for Southwest Ohio boutique hotels

A dining area with wooden tables and chairs, a wine cellar with wine racks, and a seating area with cushioned sofas.
A table with a glass of orange juice on a balcony overlooking a cityscape with buildings and a tower.
A spiral staircase with a black metal railing and a white wall.
A large banquet hall with round tables, black chairs, and white tablecloths.

1. 21c Museum Hotel Cincinnati

21c Museum Hotel Cincinnati
Downtown Cincinnati
United States
Abbygail
₹14,603
₹17,902 total
includes taxes & fees
25 Oct - 26 Oct
21c Museum Hotel Cincinnati
View all properties

Top Southwest Ohio Hotel Reviews

Explore a world of travel with Expedia