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Check availability on Southern Illinois Luxury Hotels

Tonight
3 Oct - 4 Oct
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4 Oct - 5 Oct
Next weekend
9 Oct - 11 Oct
In two weeks
16 Oct - 18 Oct

Our top choices for Southern Illinois luxury hotels

A modern spa room with a large hot tub, a glass wall with a reflective pattern, and a ceiling with a skylight.
A casino interior with slot machines, a large chandelier, and a carpeted floor.
A hotel lobby with a marble floor, a reception desk, a sign for 'Restrooms', and a large chandelier.
A hotel reception desk with a modern chandelier, a sign indicating 'SPA' coming soon, and two receptionists at their stations.

1. Walker's Bluff Casino Resort

Walker's Bluff Casino Resort
Carterville
  • Indulge in a luxurious retreat featuring a full-service spa, indoor pool, and casino gaming in the heart of Carterville.
₹11,205
₹12,435 total
includes taxes & fees
6 Oct - 7 Oct
Walker's Bluff Casino Resort
A cozy living room with a leather sofa, a fireplace, and a chandelier.
A dining area with round tables, chairs, and a chandelier.
A two-story house with a porch, a brick foundation, and an American flag.
A living room with a brown leather sofa, a beige armchair, and a matching ottoman. There are two side tables with lamps, a chandelier, and a framed portrait on the wall.

2. Charleston House Bed & Breakfast Inn

Charleston House Bed & Breakfast Inn
Charleston
₹8,772
₹9,735 total
includes taxes & fees
5 Oct - 6 Oct
Charleston House Bed & Breakfast Inn
A modern hotel lobby with a glass facade, seating area, and a staircase.
A modern dining area with a long table set for a meal, large windows offering a view of a bridge, and a stone accent wall.
A couple relaxing by a window overlooking a bridge and water.
A room with large windows overlooking a bridge and water, featuring wooden chairs and a small table.

3. Four Seasons Hotel St Louis

Four Seasons Hotel St Louis
Downtown St. Louis
  • Lavish riverside luxury awaits at the Four Seasons St. Louis with spa indulgences and poolside bliss.
₹36,116
₹42,230 total
includes taxes & fees
4 Oct - 5 Oct
Four Seasons Hotel St Louis
A hotel with a swimming pool, lounge chairs, and a courtyard with palm trees.
A grand lobby with a central seating area, a staircase, and a decorative ceiling.
An outdoor patio with a brick fireplace, wicker furniture, and a dining table set with food and drinks.
A bar area with a marble counter, bar stools, and a variety of liquor bottles.

4. The Royal Sonesta Chase Park Plaza St. Louis

The Royal Sonesta Chase Park Plaza St. Louis
Central West End
  • Indulge in historic elegance at this St. Louis gem featuring 3 restaurants, a spectacular pool area, and luxurious rooms near Forest Park.
₹15,506
₹21,125 total
includes taxes & fees
1 Nov - 2 Nov
The Royal Sonesta Chase Park Plaza St. Louis
A restaurant with round tables and chairs, a bar area, and a patterned ceiling.
An indoor swimming pool with clear glass walls, a tiled floor, and a 'Step Down' sign.
A spa bath with a sign indicating a capacity of 8 persons.
A lobby with a reception desk, seating area with sofas and ottomans, and a patterned rug.

5. Drury Plaza Hotel St. Louis Brentwood

Drury Plaza Hotel St. Louis Brentwood
Brentwood
₹12,808
₹15,208 total
includes taxes & fees
1 Nov - 2 Nov
Drury Plaza Hotel St. Louis Brentwood
A modern hotel lobby with a long reception desk, blue seating area, and a staircase leading to upper floors.
A casino resort with multiple gaming tables and a large screen displaying the resort's logo.
A modern reception area with a central emblem, linear ceiling lights, and a patterned floor.
A pool area with multiple lounge chairs and umbrellas, a pool, and a modern building in the background.

6. Terre Haute Casino Resort - Adults Only

Terre Haute Casino Resort - Adults Only
Terre Haute
₹10,461
₹12,030 total
includes taxes & fees
26 Oct - 27 Oct
Terre Haute Casino Resort - Adults Only
An indoor swimming pool with clear glass walls, metal railings, and a tiled floor.
A modern tavern with a large sign, glass doors, and indoor seating visible through the windows.
A bar area with multiple seating arrangements, a stage, and a chandelier.
A bakery display case with various pastries and cakes.

7. Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa
St. Charles
  • Indulge in lavish comfort at this St. Charles retreat featuring a full-service spa, seasonal pool, and 6 exceptional restaurants.
₹16,291
₹20,637 total
includes taxes & fees
12 Oct - 13 Oct
Ameristar Casino Resort and Spa
A multi-story building with a symmetrical facade, large windows, and a central entrance with a canopy.
A spacious lobby with a large spherical sculpture, a seating area, and a view of the outside through a large window.
A reception area with a curved wooden desk, a laptop, and a chair. The wall has a sign reading "Locust Street Athletic and Swim Club."
A spacious lobby with multiple seating areas, a pool table, and artwork on the walls.

8. 21C Museum Hotel St Louis

21C Museum Hotel St Louis
Downtown West
  • Indulge in artistic luxury at this city centre St. Louis hotel with spa services and indoor pool.
₹13,835
₹16,658 total
includes taxes & fees
25 Oct - 26 Oct
21C Museum Hotel St Louis
A spacious lobby with a curved staircase, large windows, and a seating area with a rug.
A modern bar area with a herringbone patterned wall, a long counter with bar stools, and a variety of bottles and glasses.
A hotel room with two beds, a desk, a chair, and a view of the city.
A modern living room with a large sectional sofa, a flat-screen TV, and a view of the sea through large windows.

9. The Riverview

The Riverview
Cape Girardeau
₹10,017
₹11,301 total
includes taxes & fees
4 Oct - 5 Oct
The Riverview
A living room with a beige sofa, a round coffee table, and a wooden cabinet with glass doors.
A hallway with wooden flooring, a door at the end, and a sign above reading "B&B".
A living room with a fireplace, a blue sofa, a white armchair, and a wooden ceiling.
A kitchen with a central island, wooden cabinets, and a dining area with red chairs.

10. The Respite Bed and Breakfast

The Respite Bed and Breakfast
Paducah
  • Luxury riverfront bed and breakfast with private patios offers elegant comfort in Paducah's cultural heart.
₹12,144
₹15,003 total
includes taxes & fees
3 Nov - 4 Nov
The Respite Bed and Breakfast
View all properties

Top Southern Illinois Hotel Reviews

Drury Plaza Hotel Mt. Vernon

Drury Plaza Hotel Mt. Vernon

10/10 Excellent
"Great"
Mary 1-night trip
Posted 2 hours ago
Drury Plaza Hotel Mt. Vernon
Country Inn & Suites by Radisson, Marion, IL

Country Inn & Suites by Radisson, Marion, IL

10/10 Excellent
"This is an excellent hotel to stay at. Updated, easy parking, staff is very friendly, breakfast is great, will stay at this hotel again."
Lisa 3-night trip
Posted 6 days ago
Country Inn & Suites by Radisson, Marion, IL

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