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Check availability on Southern Illinois Business Hotels

Tonight
21 Oct - 22 Oct
Tomorrow
22 Oct - 23 Oct
This weekend
23 Oct - 25 Oct
Next weekend
30 Oct - 1 Nov

Our top choices for Southern Illinois business-friendly hotels

A Holiday Inn Express & Suites building with a modern design, featuring a covered entrance and illuminated pillars.
A modern kitchen with a wooden cabinet, coffee maker, and storage shelves.
An outdoor patio area with tables and chairs, large windows, and a stone wall.
A hotel room with two beds, a large window, and a wall-mounted lamp.

1. Holiday Inn Express & Suites Mount Vernon by IHG

Holiday Inn Express & Suites Mount Vernon by IHG
Mount Vernon
United States
Doug
₹10,822
₹12,200 total
includes taxes & fees
31 Oct - 1 Nov
Holiday Inn Express & Suites Mount Vernon by IHG
A bar area with a long counter, multiple chairs, and hanging light fixtures.
A hotel lobby with a Kitchen+Bar area, seating arrangements, and a view to the outside.
A spacious lobby with a reception desk, seating area, and glass doors leading outside.
An indoor swimming pool with a metal ladder, a warning sign about cold weather, and a view of the outside.

2. Drury Plaza Hotel Mt. Vernon

Drury Plaza Hotel Mt. Vernon
Mount Vernon
United States
Richard
₹10,536
₹11,883 total
includes taxes & fees
26 Oct - 27 Oct
Drury Plaza Hotel Mt. Vernon
A hotel lobby with a reception desk, seating area, and a large screen TV.
A hotel dining area with a large wooden table, red upholstered chairs, a flat-screen TV mounted above the fireplace, and a kitchen area in the background.
A brick building with a patio area featuring wicker furniture and a table.
A Comfort Suites hotel with a spacious parking lot and a modern brick facade.

3. Comfort Suites Mount Vernon

Comfort Suites Mount Vernon
Mount Vernon
United States
Bruce and Robin
₹11,273
₹12,700 total
includes taxes & fees
25 Oct - 26 Oct
Comfort Suites Mount Vernon
A La Quinta hotel with a stone facade, a covered entrance, and a parking lot.
An indoor swimming pool with lounge chairs and a clear view of the pool area.
A modern kitchen area with a counter, various appliances, and food display items.
A modern hotel lobby with a large sun-shaped artwork, multiple seating areas, and a patterned rug.

4. La Quinta Inn & Suites by Wyndham Effingham

La Quinta Inn & Suites by Wyndham Effingham
Effingham
United States
Steve
₹10,247
₹11,475 total
includes taxes & fees
25 Oct - 26 Oct
La Quinta Inn & Suites by Wyndham Effingham
An indoor swimming pool with a view of the outside, a hot tub, and a seating area with tables and chairs.
A spacious lobby with high ceilings, a wooden ceiling, and a large wall with vertical panels. There are seating areas with sofas and chairs, and a staircase on the right.
A hotel room with two beds, a desk, a chair, a TV, and a balcony with a view.
A modern indoor seating area with leather chairs and tables, a central round table, and a staircase leading to an upper level.

5. DoubleTree by Hilton Mt. Vernon

DoubleTree by Hilton Mt. Vernon
Mount Vernon
United States
Kenneth
₹11,266
₹12,693 total
includes taxes & fees
30 Oct - 31 Oct
DoubleTree by Hilton Mt. Vernon
A modern living room with a fireplace, a bookshelf, a large wall clock, and a cozy seating area.
A reception area with a wooden counter, a welcome mat, and framed artwork on the wall.
A Country Inn & Suites building with a covered entrance and a parking lot.
A modern living room with a sofa, coffee table, and a dining area with chairs.

6. Country Inn & Suites by Radisson, Marion, IL

Country Inn & Suites by Radisson, Marion, IL
Marion
United States
Lisa
₹8,391
₹10,068 total
includes taxes & fees
8 Nov - 9 Nov
Country Inn & Suites by Radisson, Marion, IL
A self-service breakfast area with a coffee machine, refrigerated display case, and various food items.
A spacious lobby with a sofa, chairs, a coffee table, and a dining area with tables and chairs.
A gym with treadmills, ellipticals, and weight machines.
A Best Western hotel with a parking lot and a covered entrance.

7. Best Western Marion Hotel

Best Western Marion Hotel
Marion
United States
Cornell
₹7,266
₹8,717 total
includes taxes & fees
25 Oct - 26 Oct
Best Western Marion Hotel
A spacious lobby with a stone fireplace, a seating area with a sofa and chairs, and a television mounted on the wall.
A dining area with round tables and chairs, a kitchen with a countertop and appliances, and a hallway leading to another room.
A hotel room with two beds, a desk, a chair, a TV, and a window with curtains.
A hallway with vending machines and a carpeted floor.

8. SureStay Hotel by Best Western Whittington Rend Lake

SureStay Hotel by Best Western Whittington Rend Lake
Whittington
United States
Michelle
₹7,688
₹8,532 total
includes taxes & fees
28 Oct - 29 Oct
SureStay Hotel by Best Western Whittington Rend Lake
A banquet hall with tables set for a formal event, draped with white fabric and string lights, and a chandelier above.
A spacious restaurant with high ceilings, large windows, and a variety of seating arrangements including tables and chairs.
A Holiday Inn sign with a green logo and the name in white.
A Holiday Inn lobby with a reception desk, two armchairs, and a decorative ceiling light.

9. Holiday Inn Effingham by IHG

Holiday Inn Effingham by IHG
Effingham
United States
Penny
₹9,967
₹11,161 total
includes taxes & fees
15 Nov - 16 Nov
Holiday Inn Effingham by IHG
A hotel room with a bed, a desk, a chair, a TV, and a window with curtains.
A hotel room with a desk, a lamp, a flat-screen TV, a telephone, a microwave, and a trash bin.
A hotel with a brick facade, a flagpole with an American flag, and a parking lot with several cars.
A parking lot with a Super 8 sign, a white car, and a truck.

10. Super 8 by Wyndham Mt. Vernon IL

Super 8 by Wyndham Mt. Vernon IL
Mount Vernon
United States
Anonymous traveller
₹6,237
₹7,112 total
includes taxes & fees
2 Nov - 3 Nov
Super 8 by Wyndham Mt. Vernon IL
View all properties

Top Southern Illinois Hotel Reviews

Ramada by Wyndham Effingham

Ramada by Wyndham Effingham

10/10 Excellent
"The front desk lady was helpful and nice. Room was clean and spacious. Breakfast runs low fast"
Emily 1-night trip
Posted less than an hour ago
Ramada by Wyndham Effingham
Harrah's Metropolis Hotel & Casino - A Caesars Rewards Destination

Harrah's Metropolis Hotel & Casino - A Caesars Rewards Destination

10/10 Excellent
"It was great like always"
Jason 1-night trip
Posted 19 hours ago
Harrah's Metropolis Hotel & Casino - A Caesars Rewards Destination
Quality Inn & Suites Metropolis I-24

Quality Inn & Suites Metropolis I-24

8/10 Good
"Had to leave 2 days early for medical issues and could not get any refund."
Charles 5-night trip
Posted 21 hours ago
Quality Inn & Suites Metropolis I-24
Country Inn & Suites by Radisson, Marion, IL

Country Inn & Suites by Radisson, Marion, IL

10/10 Excellent
"I had a very pleasant stay at this property. The room was clean, had plenty of amenities and the bed was most comfortable. The staff was extremely pleasant and the Breakfasts offered had a great variety and was very delicious. It was close to my family I was visiting and convenient to restaurants' and other stores. I felt the pricing was very reasonable & somewhat cheaper compared to surrounding hotels. I will most definitely be staying here in the future. kudos to a job well-done to ALL their Staff. Ms. Colman"
Shelby 3-night trip
Posted 1 day ago
Country Inn & Suites by Radisson, Marion, IL
Drury Inn & Suites Marion

Drury Inn & Suites Marion

10/10 Excellent
"It was perfect for my son and I for SIUC homecoming"
Jeffrey 1-night trip
Posted 1 day ago
Drury Inn & Suites Marion
Quality Inn O'Fallon - St. Louis - Shiloh

Quality Inn O'Fallon - St. Louis - Shiloh

10/10 Excellent
"The only downfall was the indoor pool. I thought it would be heated. It wasn't. The kids still went in but we're shivering."
Michele 3-night trip
Posted 2 days ago
Quality Inn O'Fallon - St. Louis - Shiloh
Baymont by Wyndham Effingham

Baymont by Wyndham Effingham

10/10 Excellent
"Staff was amazing"
Ashtyn 1-night trip
Posted 2 days ago
Baymont by Wyndham Effingham
Holiday Inn Express Metropolis by IHG

Holiday Inn Express Metropolis by IHG

10/10 Excellent
"Room was nice and clean, indoor pool little chilly. Breakfast choices were good. Parking good,"
brian 2-night trip
Posted 6 days ago
Holiday Inn Express Metropolis by IHG

Frequently asked questions

How much do business-friendly hotels in Southern Illinois cost?
You'll pay between ₹10,705 and ₹13,316 per night for business-friendly hotels in Southern Illinois. Awesome deals on properties that cater to work-related travellers are a few clicks away on Expedia. These prices were available on Expedia within the past 7 days, for a hotel booking with a check-in date within the next year. Prices reflect current offers and availability is subject to change. Additional terms may apply.
What are the best business-friendly hotels in Southern Illinois?
That depends on your destination in Southern Illinois. Many business travellers to O'Fallon like to base themselves at Drury Inn & Suites St. Louis O'Fallon, IL. This 3-stars property comes with a swimming pool and complimentary breakfast. Hampton Inn O'Fallon is another top option if you're attending a conference or working remotely in O'Fallon. A swimming pool and an electric car charging station are among the handy amenities at this 2.5-stars getaway. When work takes you on the road, you can choose from multiple business-friendly hotels in Southern Illinois that have a total average guest review rating of 9.1.
How many business-friendly hotels are there in Southern Illinois?
Pick from 149 business-friendly hotels in Southern Illinois. Wherever your job is taking you, Expedia makes it a breeze to find the ideal space with the amenities you want.
What are the best cheap business-friendly hotels in Southern Illinois?
Keep costs low with Expedia's business-friendly hotels in Southern Illinois that start at ₹10,705 per night. A cheaper property in O'Fallon is Hampton Inn O'Fallon. Corporate guests rate it highly for its many amenities, including an electric car charging station and a swimming pool. If you're basing yourself in Effingham, choose Holiday Inn Express And Suites Effingham, an IHG Hotel. A swimming pool and a garden are among the conveniences provided for both business and leisure travellers. You'll find loads of free and interesting things to do wherever you go in Southern Illinois. If you have a meeting or conference in O'Fallon, try to find time to visit St. Clair Bowl. You can also go sightseeing for a song in Effingham. Mid America Motorworks, My Garage Museum is one of the best free attractions here. This price was available on Expedia within the past 7 days, for a hotel booking with a check-in date within the next year. Prices reflect current offers and availability is subject to change. Additional terms may apply.
Are there any family-friendly hotels in Southern Illinois that are also business friendly?
You'll discover some terrific family-friendly hotels that are also business friendly in Southern Illinois. If you're travelling to O'Fallon, look up Drury Inn & Suites St. Louis O'Fallon, IL. It offers handy amenities such as complimentary breakfast and a laundry service and has a 3-stars rating. Another property worth considering is Drury Inn & Suites St. Louis Fairview Heights. This 3-stars stay in O'Fallon is ideal for both leisure and business travellers and offers complimentary breakfast, a laundry service and much more. Once you've gotten work out of the way, get out and discover O'Fallon with the kids. Favourite family-friendly attractions include The Edge and St. Clair Bowl.
Why book your business-friendly hotel in Southern Illinois with Expedia?
At Expedia, we make it our job to help you locate an amazing stay at the right price. From luxurious, corporate-friendly properties to affordable hotels filled with handy amenities, you'll have your next work trip booked in a few easy clicks.
How can I find cheap business-friendly hotels in Southern Illinois?
When you're travelling for work in Southern Illinois, our "business friendly" filter will help you find the ideal hotel. From free WiFi to workspaces and meeting rooms, they have the amenities you need to be productive. Another useful tip? Refine your search by your budget and preferred star rating to view the most affordable options.
What is there to do in Southern Illinois near my business-friendly hotel?
Southern Illinois has so much to see and do, it can be tricky to figure out where to start. If you're spending a few nights in O'Fallon, The Edge is a much-loved attraction here.

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