Southeastern Indiana Trip

Book a Hotel + Flight or Car together to unlock savings

Photo by Serendipity Trip

  • Plan, book, travel with confidence

  • Better together

    Save up to ₹43,962 when you book a flight and hotel together*

  • Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package

  • Rest easy

    Plan, book, and manage your trip all in one place

Where to stay in Southeastern Indiana

Find the best Southeastern Indiana areas and neighborhoods for the activities you enjoy most. Learn more about Southeastern Indiana
Louisville Science Center which includes outdoor art

West Main Historic District

A noteworthy feature of West Main Historic District is its fantastic nightlife. While you're in town, be sure to stop and check out KFC Yum Center and Frazier International History Museum.

Find hotels in West Main Historic District

Top hotels in Southeastern Indiana

Radisson Hotel Louisville North

Radisson Hotel Louisville North

3 out of 5
505 Marriott Drive Clarksville IN
Fully refundableReserve now, pay when you stay
The price is ₹5,661 per night from 4 Mar to 5 Mar
₹5,661
₹6,396 total
4 Mar - 5 Mar
includes taxes & fees
6.8/10 (2,796 reviews)
The staff at the front desk and walking around was very friendly. The only part i didn’t like was receiving a text that housekeeping would only come by on day 3. We arrived at 530am and housekeeping was attempting to enter our room at 10:40am. When they realized it was deadbolted, they left and came ...

Reviewed on 15 Feb 2026

Radisson Hotel Louisville North
Hampton Inn New Albany Louisville West

Hampton Inn New Albany Louisville West

2.5 out of 5
411 W Spring Street New Albany IN
Fully refundableReserve now, pay when you stay
The price is ₹8,654 per night from 10 Mar to 11 Mar
₹8,654
₹9,780 total
10 Mar - 11 Mar
includes taxes & fees
8.8/10 Excellent! (763 reviews)
Everything was very pleasing.

Reviewed on 11 Feb 2026

Hampton Inn New Albany Louisville West
Big Splash Adventure Indoor Water Park & Resort

Big Splash Adventure Indoor Water Park & Resort

3.5 out of 5
8505 W State Road 56 French Lick IN
7.6/10 Good! (188 reviews)
Great service

Reviewed on 27 Jan 2026

Get rates
Big Splash Adventure Indoor Water Park & Resort
See all 1,171 properties in Southeastern Indiana
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Popular places to visit

Panorama Ohio River waterway riverboats and bridges leading to heart of downtown Louisville KY

KFC Yum Center

Catch an event at KFC Yum Center during your trip to Louisville. Stroll along the riverfront or attend a sporting event in the area.

KFC Yum Center
A fun place to go for night life.

Fourth Street Live!

You can do some window-shopping at Fourth Street Live! during your visit to Louisville. Experience the area's lively festivals and acclaimed theatre scene.

Fourth Street Live!

Louisville Palace

You can make plans for a show at Louisville Palace during your stay in Louisville. Experience the area's great live music or attend a sporting event.

Louisville Palace

Frequently asked questions

Can I cancel my flight booking to Southeastern Indiana due to COVID-19?
If you haven't booked yet, check the terms and conditions of the airline you're considering. If you've already reserved your flight to Southeastern Indiana, head to our Customer Service Portal. The information here will help determine which COVID-19 policies apply to your booking and provide advice on the next steps.
What's the best way to find cheap flights to Southeastern Indiana that have flexible change policies?
It's as easy as 1-2-3 with Expedia. Firstly, type in your preferred dates and destination and press "Search." Next, check the "No change fee" box directly below the "Flexible change policies" subheading to the left of the screen. Step 3. Reserve a cheap and flexible airfare to Southeastern Indiana.
What are some of the general tips for travellers to Southeastern Indiana during the COVID-19 outbreak?
With strict COVID-19 precautions to adhere to, travel looks a bit different these days. Here's what you should know before you jet off to Southeastern Indiana:
  • Research if any travel restrictions apply to your origin and destination before locking in a flight. Also check if there are any conditions you'll have to follow on arrival, such as proof of a negative COVID-19 test.
  • You must wear a face mask at the airport, including at security checkpoints. You should be prepared to lower your mask for identification purposes when asked by a TSA employee.
  • To minimize the risk of cross-contamination, place your boarding pass on the reader yourself and then hold it up for inspection. Do not hand your pass directly to a TSA officer.
  • TSA now allows passengers to take one container of hand sanitizer, up to 12 oz (350 ml) in size, in carry-on bags. This will need to be removed from your bag at the X-ray machine for screening.
  • Place any personal items (e.g, keys, phone and wallet) in your carry-on instead of a bin to minimize handling during screening.
  • Transport all food items in a clear plastic bag and also place them in a screening bin. Keeping food separate from your carry-on makes it less likely that a TSA officer will need to touch and open your bag for inspection.

Which airlines fly to Southeastern Indiana?
Let American Airlines fly you there. This renowned carrier operates 13307 services per month to O'Hare Intl. Airport (ORD), a Southeastern Indiana gateway.
How can I find cheap tickets to Southeastern Indiana?
An effective strategy for picking up cheap fares is to be flexible with your travel dates. Start by searching for your flight to Southeastern Indiana, then click on the "flexible dates" link to see prices for nearby days. Another handy tip? Book well ahead. For an idea of costs, was the best price for a flight to Southeastern Indiana in the last seven days.
How much is a flight to Southeastern Indiana?
In the last seven days, round-trip airfares to Southeastern Indiana sold for as low as and reached a maximum price of . For one-way journeys departing from (), the lowest price during this time was only .
What are the most popular airports to fly into in Southeastern Indiana?
Fly into O'Hare Intl. Airport (ORD) and sample the best that Southeastern Indiana has to offer. As the region's main point of entry, roughly 33491 flights land here every month.
When is the cheapest time to fly to Southeastern Indiana?
Leave for Southeastern Indiana earlier in the week and you'll usually be rewarded with more affordable fares. Tuesday is generally the cheapest day to jump on a plane, followed closely by Monday. If you'd like to avoid the priciest flights, steer clear of Saturdays.
How much is a plane ticket to Southeastern Indiana?
In the last seven days, airfares ranged between and . Scroll through our sensational deals to Southeastern Indiana, pick your favourite and then get ready for your getaway!
Which airlines with flights to Southeastern Indiana employ COVID-19 cleanliness policies?
While flying in the middle of a pandemic can be nerve-wracking, airlines have been working hard to ensure the well-being of all on board. Here are a few carriers that have implemented changes:
  • United Airlines - this airline is known for providing passenger masks and cleaning with disinfectant.
  • American Airlines - this airline is known for providing passenger masks and cleaning with disinfectant.
  • Delta - this airline is known for electrostatic cleaning and cleaning with disinfectant.

Explore a world of travel with Expedia

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.