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Check availability on Santo Spirito Spa Hotels

Our top choices for Santo Spirito hotels with a spa

Front of property
Palese Profumo di Mare

Palese Profumo di Mare

Palese Profumo di Mare
Municipio 5
6.6 out of 10, (11)
"Very nice right on the beach across from fish market but well worth the price . A good walkable location to restaurants and local shops."
United States
Paul
Palese Profumo di Mare
Exterior
JR Hotels Bari Grande Albergo delle Nazioni

JR Hotels Bari Grande Albergo delle Nazioni

JR Hotels Bari Grande Albergo delle Nazioni
5.0 star property
Municipio 1
8.8 out of 10, Excellent, (830)
"Great place "
Canada
Tom
JR Hotels Bari Grande Albergo delle Nazioni
Deluxe Room, 1 Double Bed | Frette Italian sheets, premium bedding, down duvets, memory-foam beds
B&B Arco Caputi

B&B Arco Caputi

B&B Arco Caputi
Ruvo di Puglia
10.0 out of 10, Exceptional, (1)
"Ottima esperienza, stanza arredata con gusto ed eleganza con tutti i comfort. Ottima accoglienza è disponibilità Posizione ottima Consigliatissimo"
Italy
lucia
The price is ₹5,071
₹7,170 total
includes taxes & fees
18 Dec - 19 Dec
B&B Arco Caputi
Daily buffet breakfast (EUR 7.00 per person)
Casa Borgo Regina B&B Bari

Casa Borgo Regina B&B Bari

Casa Borgo Regina B&B Bari
Noicattaro
8.4 out of 10, Very good, (25)
"The B&B was very clean . Very good location.The host was very helpful."
Ireland
vivian
The price is ₹4,585
₹5,044 total
includes taxes & fees
13 Jan - 14 Jan 2026
Casa Borgo Regina B&B Bari
Family Townhome | Private kitchen | Electric kettle, high chair
CASA DEGLI AMICI

CASA DEGLI AMICI

CASA DEGLI AMICI
Ruvo di Puglia
10.0 out of 10, Exceptional, (6)
"My brother and I had a wonderful stay. It was clean. The owners were very helpful. The location was perfect for us! Thank you!"
United States
Karen
The price is ₹7,067
₹8,940 total
includes taxes & fees
22 Dec - 23 Dec
CASA DEGLI AMICI
Indoor spa tub
TENUTA GENTILE RESORT & SPA

TENUTA GENTILE RESORT & SPA

TENUTA GENTILE RESORT & SPA
Cassano delle Murge
8.2 out of 10, Very good, (55)
"Amazing place great location room had amazing views staff were very helpful all facilities were great would highly recommend "
United Kingdom
Anonymous traveller
The price is ₹6,820
₹7,501 total
includes taxes & fees
14 Dec - 15 Dec
TENUTA GENTILE RESORT & SPA
Exterior
Casale Torre San Magno

Casale Torre San Magno

Casale Torre San Magno
Corato
8.0 out of 10, Very good, (25)
"Very nice compound. Friendly staff and nice breakfast and dinner."
Italy
Raul
Casale Torre San Magno
Property entrance
Hotel Federiciano

Hotel Federiciano

Hotel Federiciano
3.0 star property
Valenzano
9.2 out of 10, Wonderful, (249)
"What I liked about this property, was that you had plenty of parking outside the hotel. Hotel was very clean and accommodating to your needs. "
United States
Marco
The price is ₹6,861
₹7,547 total
includes taxes & fees
1 Jan - 2 Jan 2026
Hotel Federiciano
Panoramic Room | Frette Italian sheets, premium bedding, down duvets, in-room safe
CASA RUBIS

CASA RUBIS

CASA RUBIS
Ruvo di Puglia
10.0 out of 10, Exceptional, (2)
"Gentile accoglienza"
Italy
adolfo
The price is ₹4,994
₹6,555 total
includes taxes & fees
18 Dec - 19 Dec
CASA RUBIS
Interior
Parco dei Principi Hotel Congress & Spa

Parco dei Principi Hotel Congress & Spa

Parco dei Principi Hotel Congress & Spa
4.0 star property
Municipio 5
8.8 out of 10, Excellent, (808)
"Great hotel close to the airport!"
Canada
William
Parco dei Principi Hotel Congress & Spa
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Santo Spirito Hotel Reviews

The Nicolaus Hotel

The Nicolaus Hotel

10/10 Excellent
"Staff is great, we enjoyed the stay. Will definitely come back!!"
Varoujan 3-night trip
Posted 3 days ago
The Nicolaus Hotel

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Frequently asked questions

Looking for a spa hotel in Santo Spirito?
Soothe the senses with some time in one of our wonderful spa hotels. Hotels with spas are the perfect way to break out of your routine and add a layer of luxury to your weekend away.
What is the best spa hotel in Santo Spirito?
Palese Profumo di Mare is a top beach spa hotel featuring a rooftop terrace, a hair salon and a restaurant. Enjoy a deep-tissue massage or hot tub at the on-site spa. In-room massages are also available.
How many spa hotels are there in Santo Spirito?
Among Expedia's 40 accommodation options in Santo Spirito, there is 1 spa hotel.
What's there to see and do in Santo Spirito?
Enjoy Santo Spirito with a stop at Lido San Francesco, Fiera del Levante and Bari Harbor. If you have spare time during your trip, you might want to make a stop at Norman-Hohenstaufen Castle and Basilica of San Nicola.
What is a Santo Spirito spa hotel?
Spa hotels in Santo Spirito provide lodging and have an on-site spa which offers services including therapies as well as beauty treatments. Some also offer in-room treatments. Spa hotels are great for rest, rejuvenation and relaxation.