Photo by Sarah Mack

Search Luxury Hotels in Santiago Island

    calendar shield illustration

    Change your mind

    Book hotels with free cancellation
    deals illustration

    Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in
    bed illustration

    Be picky

    Search almost a million properties worldwide

Check availability on Santiago Island Luxury Hotels

Tonight
21 Jul - 22 Jul
Tomorrow
22 Jul - 23 Jul
This weekend
25 Jul - 27 Jul
Next weekend
1 Aug - 3 Aug

Top Santiago Island Luxury Hotels

Top Santiago Island Hotel Reviews

Frequently asked questions

Are you searching for a great accommodation for your luxury trip to Santiago Island?
Use Expedia to arrange your flight to Isla Baltra (GPS-Seymour) airport, and then choose from a variety of places to stay that will deliver the luxury you seek. Amenities are important when you plan a trip, so we make it easy to find what you'd like to make your stay relaxing and comfortable. If you want an upscale hotel with a spa, an indoor pool or luxury bedding, Expedia can help you find the best luxury hotel experience that Santiago Island offers. Santiago Island has some interesting things to see and do including Galapagos National Park and Mosquera Island, so you might want to take in the local sights during your visit.
When can I expect good weather in Santiago Island?
Planning for the weather is an important factor for making your trip to Santiago Island a success, especially when you're splurging. The hottest months are usually January and February, with an average temperature of 29°C, while the coldest months are August and September, with an average of 23°C. Average annual precipitation for Santiago Island is 598 mm.
What's there to see and do in Santiago Island?
When you're in Santiago Island, enjoy exploring the sights and attractions here including Galapagos National Park, Mosquera Island and Puerto Egas.