trover photo by Vivian Rennó

Santa Cruz Hotels from Rs6,919

Search over 1 million properties and 550 airlines worldwide

Search over 1 million flights, hotels, packages, and more

No Expedia cancellation fee to change or cancel almost any hotel reservation

Top 10 Hotels in Santa Cruz

Santa Cruz Plaza
4 out of 5
Plaza De Armas 286, Santa Cruz, O'Higgins
Free cancellationReserve now, pay when you stay
Rs10,785
per night
Jan 26 - Jan 27
4.3/5Excellent! (158 reviews)

"Good Location on the square, with a nice pool and spa area"…"

Reviewed on 13 Dec 2019

Santa Cruz Plaza
Hotel Cava Colchagua
2.5 out of 5
Barreales´s Way, 3km from Santa Cruz Square, Santa Cruz, O'Higgins
Free cancellationReserve now, pay when you stay
Rs10,620
per night
Jan 26 - Jan 27
4.5/5Wonderful! (75 reviews)
Sleep in a wine barrel.

"Unique and wonderful place to stay. Staff spoke English and very helpful in making arrangements at restaurants and for activities. Only problem was internet was unreliable."…"

Reviewed on 27 Mar 2019

Hotel Cava Colchagua
La Perla Hotel
3.5 out of 5
El Rosal, Parcela 4, Lote A, Capellanía, Santa Cruz, O'Higgins
Rs7,056
per night
Feb 2 - Feb 3
4.6/5Exceptional! (39 reviews)

"Wonderful bed Food well worth eating and sublime wine"…"

Reviewed on 24 Dec 2019

La Perla Hotel
Barrica Lodge
3.5 out of 5
Free cancellationReserve now, pay when you stay
Rs9,194
per night
Feb 2 - Feb 3
4.6/5Exceptional! (17 reviews)

"Beautiful stay. A must if you are in area. Even better than the pictures suggest!"…"

Reviewed on 2 Jan 2020

Barrica Lodge
TerraViña
3 out of 5
Camino Los Boldos S/n, Santa Cruz, O'Higgins
Free cancellationReserve now, pay when you stay
Rs11,404
per night
Jan 31 - Feb 1
4.6/5Exceptional! (116 reviews)

"Very relaxing in a great setting amongst vineyards. Pool needed cleaning. Dead flys and bugs floating around in it. Restaurant was closed on Monday night and walked through vineyards to next door restaurant. Was very dark and a bit scary coming back. Big spacious rooms with balcony"…"

Reviewed on 16 Jan 2020

TerraViña
Hotel Boutique Vendimia Premium
3.5 out of 5
Ismael Valdes 92, Santa Cruz, O'Higgins
Rs9,479
per night
Feb 2 - Feb 3
4.5/5Wonderful! (99 reviews)
Only stay with significant discount.

"I struggled to put my finger on why I was so aggrieved by my stay at this venue. The staff are friendly and the rooms are clean, what’s not to love, right? In short, this venue would make a perfectly good cheap and cheerful home stay on AirBnB but it is absolutely not a boutique hotel. Which is what ..."…"

Reviewed on 6 Sep 2019

Hotel Boutique Vendimia Premium
Hotel Hoja de Parra
3 out of 5
Calle Chomedahue, Referencia Carretera I-760, Santa Cruz, O'Higgins
Free cancellationReserve now, pay when you stay
Rs6,919
per night
Jan 26 - Jan 27
4.5/5Wonderful! (6 reviews)

"Ah-mazing! The innkeepers were so accommodating & hands on. Their personal touch made our stay extra special. We could not get over the farm fresh eggs (from the property) in the morning. They were seriously the best scrambled eggs I've ever had in my life. They were readily available for restaurant ..."…"

Reviewed on 24 Nov 2018

Hotel Hoja de Parra
Hotel Boutique Solaz Bella Vista de Colchagua
3 out of 5
San Pedro de Callihue Lote 5 J, Santa Cruz, O'Higgins
Free cancellationReserve now, pay when you stay
Rs13,036
per night
Jan 26 - Jan 27
4.6/5Exceptional! (72 reviews)
Wow

"Family owned and run. Beautiful property."…"

Reviewed on 20 Jul 2019

Hotel Boutique Solaz Bella Vista de Colchagua
Hotel Casa Pando
2.5 out of 5
Cabello 421, Santa Cruz, O'Higgins
Free cancellationReserve now, pay when you stay
Rs7,840
per night
Feb 2 - Feb 3
4.7/5Exceptional! (43 reviews)

"The owners were very helpful and helped arrange a number of different activities for us. They were always available to give us directions and advice."…"

Reviewed on 27 Feb 2019

Hotel Casa Pando
Hotel Casa de Campo
3.5 out of 5
Fundo Santa Maria de Viego 2, Carretera Del Vino Km 40, Santa Cruz, O'Higgins
Get Rates
3.8/5Good! (4 reviews)
Brilliant hotel!

"Room and bed were fantastic, nice and clean, very stylish, beautiful view of the gardens from the doors. Staff were brilliant and very attentive even though we were up a long time before breakfast had started, they still made us sandwiches and fruit for us to take on our journey. Only one thing I ..."…"

Reviewed on 8 Nov 2017

Hotel Casa de Campo
Can't see what you're looking for?
See all available properties in Santa Cruz
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Visiting Santa Cruz

Visitors to Santa Cruz are sure to enjoy the wineries, tours and restaurants. Tourists can also enjoy so much more including its casinos. You'll find 39 Expedia hotels and other accommodation options in the larger area of San Fernando.

Dressing for Santa Cruz

  • About 0 millimetres of rain falls on Santa Cruz each year

Frequently asked questions

Santa Cruz Hotel Reviews

More trip options