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Check availability on Santa Cruz Luxury Hotels

Our top choices for Santa Cruz luxury hotels

Camino Real Hotel

Camino Real Hotel
4.5 star property
Santa Cruz
8.8 out of 10, Excellent, (407)
"The parrots. Unique"
United States
Juan P
The price is ₹16,179
₹16,179 total
25 Dec - 26 Dec
Camino Real Hotel

Marriott Santa Cruz de la Sierra Hotel

Marriott Santa Cruz de la Sierra Hotel
5.0 star property
Santa Cruz
9.0 out of 10, Wonderful, (211)
"Great hotel, food and location albeit a little expensive "
United States
Reinaldo
The price is ₹9,995
₹9,995 total
26 Dec - 27 Dec
Marriott Santa Cruz de la Sierra Hotel

Swissôtel Santa Cruz De La Sierra

Swissôtel Santa Cruz De La Sierra
4.5 star property
Santa Cruz
9.2 out of 10, Wonderful, (81)
"Beautiful hotel"
Australia
Joanna
The price is ₹13,303
₹13,303 total
1 Jan - 2 Jan 2026
Swissôtel Santa Cruz De La Sierra

TRYP by Wyndham Santa Cruz

TRYP by Wyndham Santa Cruz
4.0 star property
Santa Cruz
9.2 out of 10, Wonderful, (145)
"Nice stay with good service "
United States
Jianyuan
The price is ₹8,898
₹8,898 total
12 Dec - 13 Dec
TRYP by Wyndham Santa Cruz

Hampton by Hilton Santa Cruz/Equipetrol, Bolivia

Hampton by Hilton Santa Cruz/Equipetrol, Bolivia
4.5 star property
Santa Cruz
9.2 out of 10, Wonderful, (253)
"Nice hotel "
United States
Narciso Lorenzo
The price is ₹5,753
₹5,753 total
21 Dec - 22 Dec
Hampton by Hilton Santa Cruz/Equipetrol, Bolivia

Novotel Santa Cruz De La Sierra

Novotel Santa Cruz De La Sierra
5.0 star property
Santa Cruz
9.2 out of 10, Wonderful, (103)
"Great location and very clean hotel. Will stay again soon."
United States
William
The price is ₹8,988
₹8,988 total
26 Dec - 27 Dec
Novotel Santa Cruz De La Sierra
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find out more about Santa Cruz

Santa Cruzand its attractions for luxury travelers

Santa Cruz, Bolivia, offers a blend of luxury and adventure that is perfect for discerning travellers. Begin your journey at the stunning Biocentro Güembé, a lavish tropical park where you can relax in a high-end spa or stroll through beautifully landscaped gardens filled with exotic wildlife. Next, explore the vibrant Mercado Los Pozos, where you can delight in an array of local crafts and flavours, perhaps picking up some unique Bolivian souvenirs. For a taste of culture, visit the impressive Museo de Arte Contemporáneo, showcasing contemporary works that reflect the country's rich heritage. Spend an afternoon at the exclusive Equipetrol neighbourhood, known for its upscale dining and boutique shops, providing a perfect backdrop for a leisurely lunch or an evening of fine dining. Finally, don't miss the chance to unwind at the Parque El Arenal, a serene oasis in the city where you can enjoy a leisurely stroll or a picnic with your family. When it comes to accommodation, luxury hotels in the Equipetrol area offer elegant rooms and exceptional service, ensuring you feel pampered during your stay. From fine dining options to personalised concierge services, these hotels create a perfect launchpad for your Santa Cruz adventures.

Find the best luxury hotels and resorts in Santa Cruz

For discerning travellers seeking a lavish getaway in Santa Cruz, these hotels offer unparalleled luxury and comfort, ensuring a memorable stay.

Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel

  • Why it's great for a luxury retreat: Los Tajibos impresses luxury travellers with its refined ambiance and a solid guest review rating of 9.0. Highlights include a 24-hour restaurant, a rejuvenating spa with hydrotherapy treatments, and plush premium bedding, ensuring a restful retreat. Guests can unwind in the hot tub or enjoy the elegance of room service that operates around the clock.
  • Other amenities: Additional features include a terrace for evening relaxation, a fitness centre for those wishing to maintain their routine, and complimentary buffet breakfast. The hotel also offers exclusive spa treatments such as body wraps and scrubs, along with convenient airport shuttles, making it a haven for luxury and comfort.
  • Nearby attractions: Santa Cruz Zoo - 1.4 km, Patio Design LifeStyle Center - 1.4 km, Ventura Mall - 2.3 km

Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel

  • Why it's great for a luxury retreat: Located in the heart of Santa Cruz, Los Tajibos stands out with a remarkable guest review rating of 9.0. This luxurious hotel features a 24-hour restaurant and room service, ensuring guests can enjoy a delightful dining experience at their convenience. With premium bedding, guests can expect restful nights, complemented by the attentive concierge service that meets every traveller's desire.
  • Other amenities: The hotel also offers a range of spa services, including hydrotherapy treatments, body scrubs, and couples treatment rooms, enhancing the overall luxury experience. Other features include a hot tub, private balconies, and a fitness centre for those who wish to maintain their routine. Additional conveniences such as free buffet breakfast, self-parking, and nearby shopping districts elevate the level of comfort for guests.
  • Nearby attractions: Santa Cruz Zoo - 1.4 km, Patio Design LifeStyle Center - 1.4 km, Ventura Mall - 2.3 km

Marriott Santa Cruz de la Sierra Hotel

  • Why it's great for a luxury retreat: The Marriott Santa Cruz de la Sierra Hotel epitomises luxury, a stellar review rating of 9.0. Featuring spacious executive rooms with access to an exclusive lounge, guests can enjoy enhanced privacy and comfort. The onsite spa offers a variety of treatments, while room service ensures dining can be enjoyed in the comfort of your own space.
  • Other amenities: The hotel also features an outdoor pool with sun loungers, tennis courts for an active lifestyle, and beautiful rooftop gardens for relaxation. Additional benefits include housekeeping services, free toiletries, fitness facilities, and self-parking, all designed to provide a straightforward experience for discerning travellers.
  • Nearby attractions: Santa Cruz Zoo - 2.4 km, Patio Design LifeStyle Center - 1.9 km, Ventura Mall - 0.7 km

Camino Real Hotel

  • Why it's great for a luxury retreat: The Camino Real Hotel is a splendid choice for luxury travellers, an impressive guest review rating of 8.8. With a stunning poolside bar and a swim-up bar, guests can indulge in refreshing cocktails while basking in the sun. The hotel also features a beautifully designed garden-view restaurant, perfect for enjoying exquisite meals in a serene environment, complemented by 24-hour room service and a dedicated concierge to cater to every need.
  • Other amenities: Guests can unwind in the onsite spa with treatment rooms offering massage services, or relax in the indoor and outdoor pools, complete with hydromassage showerheads and pool umbrellas. The hotel also provides an array of conveniences such as free buffet breakfast, airport transportation, and babysitting services, making it ideal for both relaxation and convenience. With a shopping district nearby, guests can easily explore local offerings.
  • Nearby attractions: Santa Cruz Zoo - 2 km, Patio Design LifeStyle Center - 2.2 km, Ventura Mall - 0.8 km

Sun Hotel

  • Why it's great for a luxury retreat: The Sun Hotel is an excellent option for luxury travellers, with an excellent guest review rating of 8.2. This hotel offers 24-hour room service and designer toiletries, ensuring guests feel pampered throughout their stay. With a concierge on hand, all requests can be accommodated, making this hotel an appealing choice for those seeking a refined experience.
  • Other amenities: Guests can indulge in spa services, including manis and pedis, reflexology, and body treatments. The outdoor pool and hot tub provide a perfect setting for relaxation, while the hotel also offers free buffet breakfast. Other conveniences include airport transportation, a sauna, and a beautiful garden area for leisurely strolls.
  • Nearby attractions: Play Land Amusement Park - 2.6 km, Univalle - 8.8 km

Top Santa Cruz Hotel Reviews

Frequently asked questions

Are you looking for a luxury hotel for your Santa Cruz holiday?
Fly into Santa Cruz (VVI-Viru Viru Intl.) Airport and then pamper yourself by staying at one of 7 Santa Cruz luxury hotels. Santa Cruz has some interesting things to see and do including Plaza 24 de Septiembre and Blacutt Square, so you might want to take in the local sights during your visit.
What's the best high-end hotel in Santa Cruz?
Marriott Santa Cruz de la Sierra Hotel is a luxury hotel with a full-service spa and a rooftop terrace, and it's a popular choice for Expedia travellers looking for an elegant place to stay. Novotel Santa Cruz De La Sierra and Camino Real Hotel are two other upscale options for your trip.
How many luxury hotels are there in Santa Cruz?
Lie in the lap of luxury during your getaway to Santa Cruz in one of Expedia's 7 luxury hotels.
When can I expect good weather in Santa Cruz?
Planning for the weather is a good way to make your trip to Santa Cruz relaxing and enjoyable, especially when you're splurging. The hottest months are usually October and November, with an average temperature of 26°C, while the coldest months are June and July, with an average of 21°C. Average annual precipitation for Santa Cruz is 1208 mm.
What's there to see and do in Santa Cruz?
Enjoy all that Santa Cruz has to offer when you visit Plaza 24 de Septiembre, Blacutt Square and Ramon Tahuichi Aguilera Stadium. If you have a little extra time during your trip, you might want to make a stop at Santa Cruz Zoo and Ventura Mall.
How can I get around Santa Cruz?
It's easier to get around town comfortably when you know your options. To venture out into the surrounding area, hop aboard a train at Santa Cruz de la Sierra Station.