Default HTG hotel image

Search Holiday Rentals in Santa Cruz

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

In two weeks
18 Sept - 20 Sept
In two months
30 Oct - 1 Nov
In three months
27 Nov - 29 Nov
In four months
25 Dec - 27 Dec

Our top choices for Santa Cruz holiday rentals

A person relaxing in a hot tub with a scenic view of mountains and clouds.

1. Skyline Ecoliving

Skyline Ecoliving
3.0 star property
El Rosario
9.4 out of 10, Exceptional, (43 reviews)
"Exelente servicio"
United States
Ernesto
The price is ₹5,660
₹7,098 total
9 Sept - 10 Sept
Skyline Ecoliving
A restaurant with wooden tables and chairs, large windows, and a view of the street.

2. Hotel Distrito 70 Living

Hotel Distrito 70 Living
3.0 star property
Laureles - Estadio
9.6 out of 10, Exceptional, (5 reviews)
"Clean room, the breakfast was good but it was in another location"
United States
Ricardo
The price is ₹3,640
₹3,640 total
20 Sept - 21 Sept
Hotel Distrito 70 Living
A modern restaurant with high ceilings, large windows, and a city view. Tables are set with dishes and drinks.

3. Edificio Helena

Edificio Helena
3.0 star property
Medellín
8.8 out of 10, Excellent, (70 reviews)
"Awesome breakfast, great location. Great host"
United States
James
The price is ₹4,070
₹4,070 total
21 Sept - 22 Sept
Edificio Helena
A rooftop patio with tables and chairs, a bar area, and a view of the cityscape.

4. B 48 Living by B Rent

B 48 Living by B Rent
4.0 star property
Laureles - Estadio
9.8 out of 10, Exceptional, (23 reviews)
"I love the people & I love the area. One of the best place to stay in Medellin. "
United States
Lusene
The price is ₹4,703
₹4,703 total
8 Sept - 9 Sept
B 48 Living by B Rent
A modern living room with a sofa set, a coffee table, and a potted plant.

5. Metropolitan Living by HOUSY

Metropolitan Living by HOUSY
4.0 star property
San Diego
8.8 out of 10, Excellent, (84 reviews)
"Clean, good location, nice staff"
United States
Sau Yeng
The price is ₹5,039
₹7,118 total
8 Sept - 9 Sept
Metropolitan Living by HOUSY
A bedroom with a bed, a bedside table with a plant, a sofa, and a wall with a large blue arch.

6. Hotel Moore 45

Hotel Moore 45
4.0 star property
Buenos Aires
8.8 out of 10, Excellent, (3 reviews)
"I like the service and it’s really comfortable. And the people in their recession. Bety. Help. Take you guys. I Enjoy the State. I’m planning to Come Back. How old is go back to the hotel again!"
United States
Welinton
The price is ₹2,107
₹2,107 total
7 Sept - 8 Sept
Hotel Moore 45
A neatly made bed with a wooden headboard, a bedside table with a bottle and a glass, and a chair in a bright room with a large window.

7. Portal del Rodeo ApartaHotel - Arkadia Mall

Portal del Rodeo ApartaHotel - Arkadia Mall
3.5 star property
Medellín
9.2 out of 10, Wonderful, (293 reviews)
"Excellent place to stay with family and friends!"
Canada
Jose
The price is ₹5,981
₹5,981 total
7 Sept - 8 Sept
Portal del Rodeo ApartaHotel - Arkadia Mall
A modern bathroom with a marble-tiled wall, a wooden vanity, a bathtub with a built-in seat, and a handheld showerhead.

8. hotel civitas medellin

hotel civitas medellin
2.5 star property
La Candelaria
8.0 out of 10, Very good, (4 reviews)
"Hotel in a good location, comfortable and has a great staff."
United States
Valencia
The price is ₹2,682
₹2,682 total
6 Oct - 7 Oct
hotel civitas medellin
A modern interior with a large mirror, a dining area, and a sofa.

9. Urban Lofts Laureles 40

Urban Lofts Laureles 40
4.0 star property
Laureles
10.0 out of 10, Exceptional, (4 reviews)
"Great exprience. Great place. Great location."
United States
Victor
The price is ₹4,960
₹6,471 total
19 Sept - 20 Sept
Urban Lofts Laureles 40
A modern kitchen with an island, bar stools, and a dining area with a sofa and coffee table.

10. Luxury Suites Prana By Cadissa

Luxury Suites Prana By Cadissa
5.0 star property
Laureles - Estadio
9.4 out of 10, Exceptional, (57 reviews)
"The hotel is Nestled in the middle of many attractions. Whick is like a quick 15 minutes from most popular attractions. The rental is more like an apartment with a full kitchen and the rooms are air conditioned."
United States
Jimmy
The price is ₹8,888
₹12,947 total
22 Sept - 23 Sept
Luxury Suites Prana By Cadissa
A modern hotel room with a large bed, a flat-screen TV, and a view of the city through large windows.

11. Factory Lofts

Factory Lofts
4.0 star property
Laureles - Estadio
9.6 out of 10, Exceptional, (142 reviews)
"Everything was great!"
United States
Georgino Mathias
The price is ₹8,127
₹10,847 total
30 Sept - 1 Oct
Factory Lofts
A rooftop terrace with two hot tubs, a dining area with chairs and a table, and a view of a cityscape with mountains in the background.

12. Quadrato Studios

Quadrato Studios
3.0 star property
Laureles
9.4 out of 10, Exceptional, (113 reviews)
"Beautiful hotel great location great breakfast"
United States
gary
The price is ₹3,904
₹3,904 total
20 Sept - 21 Sept
Quadrato Studios
A modern hotel room with a bed, a desk, a TV, and a balcony with a view.

13. Origen Local Suites

Origen Local Suites
3.0 star property
Laureles
9.4 out of 10, Exceptional, (214 reviews)
"My favorite place to stay by far! Everything is within few blocks! Bars,discos, restaurants! You named!! The staff is like family to me ! I highly recommend this hotel!!"
United States
Luis
The price is ₹5,064
₹5,064 total
6 Oct - 7 Oct
Origen Local Suites
A modern living room with a large window, a sofa, a coffee table, and a kitchen area with a marble island.

14. Loft 43

Loft 43
3.0 star property
Laureles
8.6 out of 10, Excellent, (35 reviews)
"We stayed 1 week. The unit was clean, friendly staff and location was the best. Near several restaurants, grocery. Not noisy"
United States
Mario
The price is ₹5,049
₹5,049 total
6 Oct - 7 Oct
Loft 43
A modern bedroom with a large bed, a built-in wardrobe, a kitchen area, and a balcony with plants.

15. Living by Armoniko

Living by Armoniko
4.0 star property
Laureles
9.4 out of 10, Exceptional, (79 reviews)
"We liked the location and that they have parking on their property."
United States
Richard
The price is ₹8,885
₹9,489 total
9 Sept - 10 Sept
Living by Armoniko
A bedroom with a bed, a TV mounted on the wall, a window with a view of trees, and a kitchenette area.

16. Amaranto Suites

Amaranto Suites
3.0 star property
Laureles - Estadio
9.8 out of 10, Exceptional, (6 reviews)
"Perfect"
United States
Alexander
The price is ₹3,867
₹3,867 total
7 Sept - 8 Sept
Amaranto Suites
A staircase with black railings and wooden steps, leading to a wooden wall.

17. zenia

zenia
3.0 star property
Laureles
9.4 out of 10, Exceptional, (66 reviews)
"Room was perfect, if you’re staying for a long trip, I highly recommend getting the room with the washer. Super clean and amazing location."
United States
Kirman
The price is ₹2,956
₹2,956 total
21 Sept - 22 Sept
zenia
A modern apartment with a living area, kitchenette, and large windows offering city views.

18. Kyux by Jalo

Kyux by Jalo
4.0 star property
Laureles
9.2 out of 10, Wonderful, (160 reviews)
"Excellent place to stay."
United States
Rexford
The price is ₹6,611
₹6,611 total
13 Sept - 14 Sept
Kyux by Jalo
A residential street with a two-story house, a paved sidewalk, and a red-tiled area.

19. Jardin Loft

Jardin Loft
3.0 star property
Laureles
The price is ₹3,627
₹4,533 total
6 Sept - 7 Sept
Jardin Loft
A balcony with a view of a cityscape, including buildings and a mountain range.

20. Hotel Ivanna - Laureles

Hotel Ivanna - Laureles
4.0 star property
Laureles - Estadio
9.4 out of 10, Exceptional, (3 reviews)
"Excellent place to stay. Safe area. The staff are the best."
United States
Joseph
The price is ₹7,416
₹7,416 total
13 Sept - 14 Sept
Hotel Ivanna - Laureles
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Top Santa Cruz Hotel Reviews

Hotel San Fernando Plaza

Hotel San Fernando Plaza

10/10 Excellent
"."
Natalia Andrea 6-night trip
Posted 1 hour ago
Hotel San Fernando Plaza

Find out more about Santa Cruz

Holiday Rentals in Santa Cruz

Search for holiday rentals in Santa Cruz on Expedia.co.uk! You can easily find your home rentals, villas, holiday apartments in Santa Cruz using one of the methods below:

  • View our selection of featured holiday rentals in Santa Cruz
  • Use the map to find apartments and other holiday homes in the Santa Cruz neighbourhood you prefer
  • Enter your travel dates to view the best deals on holiday rentals in Santa Cruz while they last

Look no further and take a look at our great range of rental properties in Santa Cruz!

Frequently asked questions

Can I find a holiday rental in Santa Cruz?

Yes, there are holiday rentals close to the most popular sights in Santa Cruz, or you can select a more secluded option if you're looking for a relaxing stay.

What’s there to see and do in Santa Cruz?

While exploring the area, visit family-friendly sights like Pueblito Paisa, or get outside and enjoy nature at Medellin Botanical Garden. In the wider area, you’ll find University of Antioquia and Arvi Park.

What’s a holiday rental in Santa Cruz like?

Holiday rentals are private properties where you can stay for a few weeks, or just a few days, in Santa Cruz. Holiday rentals offer extras like WiFi and washers and dryers so you'll feel right at home. If you're concerned about a clean environment, holiday rentals can offer a sense of safety away from public hotel lifts and lobbies bustling with people while still allowing you the enjoyment of travel. You'll also find more space in a holiday rental than in a standard hotel, which is another reason why a holiday rental is a popular option for families.