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Our top choices for San Francisco hotels

A balcony with wicker chairs and a view of the cityscape.

1. Ramada Plaza by Wyndham Panama Punta Pacifica

Ramada Plaza by Wyndham Panama Punta Pacifica
4.0 star property
San Francisco
9.6 out of 10, Exceptional, (1,416 reviews)
"Great location and breakfast buffet was great"
United States
Luis
The price is ₹6,822
₹7,504 total
includes taxes & fees
11 Nov - 12 Nov
Ramada Plaza by Wyndham Panama Punta Pacifica
A multi-story hotel with a Marriott sign, surrounded by high-rise buildings and a busy street with cars.

2. Courtyard by Marriott Panama Multiplaza Mall

Courtyard by Marriott Panama Multiplaza Mall
4.0 star property
San Francisco
9.0 out of 10, Wonderful, (1,002 reviews)
"The location was perfect for the things I had planed."
United States
Marine
The price is ₹12,411
₹13,652 total
includes taxes & fees
21 Nov - 22 Nov
Courtyard by Marriott Panama Multiplaza Mall
A modern hotel with a prominent entrance, multiple floors, and a well-lit facade.

3. Aloft by Marriott Panama

Aloft by Marriott Panama
3.5 star property
San Francisco
8.8 out of 10, Excellent, (1,009 reviews)
"It was a great stay! I would stay here again!"
United States
Brittney
The price is ₹11,677
₹12,845 total
includes taxes & fees
14 Nov - 15 Nov
Aloft by Marriott Panama
A buffet with various food items and a decorative plant.

4. Sheraton Grand Panama

Sheraton Grand Panama
4.0 star property
San Francisco
8.8 out of 10, Excellent, (1,000 reviews)
"Clean rooms, comfy bed, helpful staff! Breakfast buffet was very complete with different options"
United States
Nicole
The price is ₹17,297
₹19,027 total
includes taxes & fees
13 Nov - 14 Nov
Sheraton Grand Panama
A poolside area with lounge chairs and umbrellas, overlooking a clear blue sea and a city skyline.

5. Residence Inn by Marriott Panama City

Residence Inn by Marriott Panama City
4.0 star property
San Francisco
9.2 out of 10, Wonderful, (695 reviews)
"Great place!"
United States
david
The price is ₹19,497
₹21,447 total
includes taxes & fees
4 Dec - 5 Dec
Residence Inn by Marriott Panama City
A covered outdoor seating area with a view of a city skyline and water.

6. Plaza Paitilla Inn Hotel

Plaza Paitilla Inn Hotel
3.5 star property
San Francisco
9.4 out of 10, Exceptional, (2,246 reviews)
"great stay"
Canada
Davlin
The price is ₹11,117
₹12,228 total
includes taxes & fees
9 Nov - 10 Nov
Plaza Paitilla Inn Hotel
A modern lobby with a glass railing, a central staircase, and a view of the cityscape through large windows.

7. Las Americas Golden Tower Panama

Las Americas Golden Tower Panama
4.0 star property
San Francisco
9.0 out of 10, Wonderful, (1,137 reviews)
"Breakfast was great, friendly staff, clean rooms."
United States
Everlyn
The price is ₹14,192
₹15,612 total
includes taxes & fees
22 Nov - 23 Nov
Las Americas Golden Tower Panama
A poolside area with lounge chairs and a view of the ocean.

8. JW Marriott Panama

JW Marriott Panama
5.0 star property
San Francisco
9.2 out of 10, Wonderful, (1,000 reviews)
"Beautiful hotel, Excellent hotel with great views, very clean the food was good"
United States
GIORIA
The price is ₹30,969
₹34,066 total
includes taxes & fees
28 Nov - 29 Nov
JW Marriott Panama
A modern outdoor swimming pool with a clear view of a tall building in the background.

9. Dovle Residences by HMS-Preferred Member

Dovle Residences by HMS-Preferred Member
4.0 star property
San Francisco
8.8 out of 10, Excellent, (41 reviews)
"Rooms were clean, looks just like the photos, cleaned every day. Staff was lovely, especially the ones at the restaurant! Lovely lovely experience with them! Breakfast every morning was spectacular. Did not get a chance to try the pool but it looked beautiful! 9/10 I must mention the matcha and the view from the gym, immaculate!"
United States
Obrein
The price is ₹12,161
₹13,626 total
includes taxes & fees
11 Nov - 12 Nov
Dovle Residences by HMS-Preferred Member
A high-rise building with a modern architectural design, featuring a grid of windows and balconies.

10. Megapolis Hotel Panamá

Megapolis Hotel Panamá
4.5 star property
San Francisco
8.6 out of 10, Excellent, (1,839 reviews)
"Loved our stay there"
United States
Amanda
The price is ₹15,846
₹17,431 total
includes taxes & fees
18 Nov - 19 Nov
Megapolis Hotel Panamá
A modern building with a glass facade, a curved structure, and a flat roof.

11. Decapolis Hotel Panama City

Decapolis Hotel Panama City
4.0 star property
San Francisco
8.6 out of 10, Excellent, (1,728 reviews)
"We always stay there and have a good experience, good breakfast and very nice staff"
United States
Wladimir
The price is ₹11,090
₹12,199 total
includes taxes & fees
3 Dec - 4 Dec
Decapolis Hotel Panama City
Balcony

12. San Francisco by Wynwood House

San Francisco by Wynwood House
3.0 star property
San Francisco
9.2 out of 10, Wonderful, (67 reviews)
"Wonderful location. The staff is very friendly. I highly recommend a Coffee Shop right at the entrance: "La Vasquita"."
United States
Georg
The price is ₹7,674
₹10,811 total
includes taxes & fees
6 Nov - 7 Nov
San Francisco by Wynwood House
A modern living room with a sofa, a coffee table with flowers, a TV, and a large window with a city view.

13. Boutique Apartments Panamá Coco del Mar

Boutique Apartments Panamá Coco del Mar
3.5 star property
San Francisco
7.8 out of 10, Good, (237 reviews)
"very nice place to stay"
United States
purabi
The price is ₹3,799
₹17,449 total
includes taxes & fees
30 Nov - 1 Dec
Boutique Apartments Panamá Coco del Mar
A modern living room with a sofa, a TV, a small table, and a balcony with a view of the city.

14. Living 73 Panamá by Boutique Apartments

Living 73 Panamá by Boutique Apartments
3.0 star property
San Francisco
9.0 out of 10, Wonderful, (2 reviews)
"Perfect"
United States
Lorenz
The price is ₹3,161
₹17,877 total
includes taxes & fees
10 Nov - 11 Nov
Living 73 Panamá by Boutique Apartments
A rooftop pool with lounge chairs, offering a city view.

15. Boutique Apartments Atlapa

Boutique Apartments Atlapa
3.0 star property
San Francisco
8.0 out of 10, Very good, (49 reviews)
"Staff was great. Room has spectacular views. Air conditioning was great, super quiet in the bedroom. Rooftop pool and patio was delightful. Loved our stay!"
Canada
Gary
The price is ₹3,924
₹14,685 total
includes taxes & fees
10 Nov - 11 Nov
Boutique Apartments Atlapa
A modern living room with a large sliding glass door leading to a balcony, a flat-screen TV, and a grey sofa.

16. The Hub by Boutique Apartments

The Hub by Boutique Apartments
3.0 star property
San Francisco
The price is ₹3,636
₹16,304 total
includes taxes & fees
17 Nov - 18 Nov
The Hub by Boutique Apartments
A swimming pool with lounge chairs, surrounded by greenery and modern buildings.

17. Pty Loft-style 1br Cincuentenario Bay

Pty Loft-style 1br Cincuentenario Bay
2.0 star property
San Francisco
10.0 out of 10, Exceptional, (2 reviews)
"Buenisimo todo"
Mexico
Germain
The price is ₹10,852
₹15,185 total
includes taxes & fees
19 Nov - 20 Nov
Pty Loft-style 1br Cincuentenario Bay
A hotel room with a bed, a desk, and a chair. There is a window with a view of palm trees and tall buildings.

18. Casa Orquídea

Casa Orquídea
2.0 star property
San Francisco
8.0 out of 10, Very good, (16 reviews)
"Very well located and cheap and convenient"
United States
SANTIAGO
The price is ₹5,172
₹5,690 total
includes taxes & fees
19 Nov - 20 Nov
Casa Orquídea
A modern hotel pool area with a circular hot tub, lounge chairs, and a view of the city skyline.

19. Wanders Panama by Boutique Apartments

Wanders Panama by Boutique Apartments
4.0 star property
San Francisco
10.0 out of 10, Exceptional, (4 reviews)
"The apartment was great. It was very comfortable and spacious. The building is impressive and a great place from which to enjoy Panama City. "
United States
Gary
The price is ₹9,230
₹24,705 total
includes taxes & fees
17 Nov - 18 Nov
Wanders Panama by Boutique Apartments
A restaurant with a modern glass facade, wooden seating, and a sign indicating valet parking.

20. Modern Apartments PH Living 73 SF

Modern Apartments PH Living 73 SF
3.5 star property
San Francisco
8.0 out of 10, Very good, (4 reviews)
"To the owner, it would help if the top sheet is larger than the bed, difficult for two people to cover themselves"
United States
Dawid
The price is ₹7,590
₹8,349 total
includes taxes & fees
19 Nov - 20 Nov
Modern Apartments PH Living 73 SF
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Compare popular hotels in San Francisco

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet-friendly
WiFi included
A balcony with wicker chairs and a view of the cityscape.
Ramada Plaza by Wyndham Panama Punta Pacifica
4.0 star property
9.6
Exceptional
1,416 reviews
View
A multi-story hotel with a Marriott sign, surrounded by high-rise buildings and a busy street with cars.
Courtyard by Marriott Panama Multiplaza Mall
4.0 star property
9.0
Wonderful
1,002 reviews
View
A poolside area with lounge chairs and umbrellas, overlooking a clear blue sea and a city skyline.
Residence Inn by Marriott Panama City
4.0 star property
9.2
Wonderful
695 reviews
View
A modern hotel with a prominent entrance, multiple floors, and a well-lit facade.
Aloft by Marriott Panama
3.5 star property
8.8
Excellent
1,009 reviews
View
A covered outdoor seating area with a view of a city skyline and water.
Plaza Paitilla Inn Hotel
3.5 star property
9.4
Exceptional
2,246 reviews
View

Where to stay in San Francisco

Find the best San Francisco areas for the activities you enjoy most.
A coastal cityscape with a prominent church tower, a river, and distant mountains.

Casco Viejo

Unique features of Casco Viejo include the historical sites and bars. Make a stop by Independence Square or Interoceanic Canal Museum while you're exploring the area.

A modern, spiraling skyscraper with a unique design, surrounded by other buildings in an urban setting.
Photo by Fabiola Tile
Open Photo by Fabiola Tile

Bella Vista

Travellers love Bella Vista for its popular shops, and you can see more of Panama City by jumping on the metro at Iglesia del Carmen Station or Vía Argentina Station. You might spend time checking out top sights like Via Espana and Iglesia del Carmen.

A city skyline with modern high-rise buildings and a river in the foreground.

El Cangrejo

The ample dining options and casino gaming are top of the list for many visitors to El Cangrejo. A stop by Via Espana or Crown Casino might round out your trip.

A building with three arched windows, a balcony with wrought iron railings, and a tiled roof.

San Felipe

While visiting San Felipe, you might make a stop by sights like Independence Square and Interoceanic Canal Museum.

A coastal cityscape with high-rise buildings, a calm sea, and a rocky shoreline.

Calidonia

Calidonia is a destination travellers like for its shopping, and you might hop aboard the metro at Lotería Station or Santo Tomás Station to explore sights like Via Espana.

Top San Francisco Hotel Reviews

A balcony with wicker chairs and a view of the cityscape.
Ramada Plaza by Wyndham Panama Punta Pacifica

Ramada Plaza by Wyndham Panama Punta Pacifica

Ramada Plaza by Wyndham Panama Punta Pacifica
San Francisco

10/10 Excellent

Great location central to everywhere. Only 6 dollars in Uber to old town. Clean with loads of space. Great gym and pool area. Gave me a late check out at no extra charge. Would recommend
United Kingdom
Warren
Reviewed March 9, 2025
Ramada Plaza by Wyndham Panama Punta Pacifica

Frequently Asked Questions

What is San Francisco like?

San Francisco is a welcoming neighbourhood that travellers like for its restaurants. Make sure that you visit Multiplaza Pacific Mall and Calle 50 as part of your San Francisco travel plans.

Where is the best hotel for a stay in San Francisco?

Based on our traveller data, Megapolis Hotel Panamá is one of the top choices for your stay in San Francisco. This hotel is steps from Avenida Balboa, and offers a full-service spa and a casino. Other good choices for your stay in the area include Ramada Plaza by Wyndham Panama Punta Pacifica and Decapolis Hotel Panama City.

How many hotels can I expect to find in San Francisco?

If you're searching for places to stay in Panama City, Expedia has something to meet your needs with 323 San Francisco hotels and other accommodation options to choose from.

If I need to cancel my hotel reservation in San Francisco, will I receive a refund?

Yes! Most hotel reservations are fully refundable provided that you cancel before the hotel’s cancellation deadline, which often is within 24-48 hours of check in. If you booked a non-refundable reservation, you may still be able to cancel and be given a refund within 24 hours of booking. Add dates, click "Search", then use the filter option "fully refundable" to view the best deals in San Francisco.

What is there to do in this Panama City neighbourhood?

While you're in San Francisco, a shopping trip to Multiplaza Pacific Mall, Avenida Balboa or Via Espana might be the perfect way to find that souvenir you've been looking for. Calle 50 and Pacific Center are some other stops worth a visit in the neighbourhood. A few places to visit in the area around San Francisco include Bingo 90, Soho City Center and National Shrine of the Heart of Mary. When you're sightseeing in Panama City, Panama Viejo Museum and Multicentro Panama are also worth a stop.

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