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Our top choices for Santa Ana hotels

1. Casco View Life Residences

Casco View Life Residences
4.0 star property
Santa Ana
9.0 out of 10, Wonderful, (106 reviews)
"Always an amazing stay"
United States
chris
The price is ₹5,542
₹8,972 total
includes taxes & fees
27 Sept - 28 Sept
Casco View Life Residences

2. Hostal La Cigarra

Hostal La Cigarra
2.0 star property
Santa Ana
7.6 out of 10, Good, (73 reviews)
"Excellent staff, close to metro and embassies. A good location, good room for a great price. I would stay again. "
United Kingdom
Mark
The price is ₹2,477
₹2,759 total
includes taxes & fees
23 Sept - 24 Sept
Hostal La Cigarra

3. Hotel República

Hotel República
2.0 star property
Santa Ana
6.8 out of 10, (197 reviews)
"Good location. Walking distance to shops and public transport."
Canada
Danilo
The price is ₹2,552
₹8,585 total
includes taxes & fees
21 Oct - 22 Oct
Hotel República

4. Hotel Caracas - Casco Viejo

Hotel Caracas - Casco Viejo
3.0 star property
Santa Ana
8.0 out of 10, Very good, (16 reviews)
"great staff"
United States
Keith
The price is ₹3,560
₹3,916 total
includes taxes & fees
14 Oct - 15 Oct
Hotel Caracas - Casco Viejo

5. ART CASCO The Hotel

ART CASCO The Hotel
2.0 star property
Santa Ana
6.0 out of 10, (13 reviews)
"Walkable location and free secure parking! The price is really affordable, but the condition of the hotel is not the best"
United States
Eldris
The price is ₹2,353
₹2,588 total
includes taxes & fees
21 Sept - 22 Sept
ART CASCO The Hotel

6. Hotel Riazor

Hotel Riazor
3.0 star property
Santa Ana
3.8 out of 10, (11 reviews)
"Rough neighborhood "
Canada
Del
The price is ₹2,356
₹2,615 total
includes taxes & fees
21 Oct - 22 Oct
Hotel Riazor

7. La Manzana Barrio Vivo by Wynwood

La Manzana Barrio Vivo by Wynwood
3.0 star property
Santa Ana
7.6 out of 10, Good, (19 reviews)
"Very clean and safe property"
United States
Javier Alberto Lindauer
The price is ₹6,601
₹9,898 total
includes taxes & fees
21 Sept - 22 Sept
La Manzana Barrio Vivo by Wynwood

8. Room-sofa Bed Stay Rooftop Pool & Gym, A

Room-sofa Bed Stay Rooftop Pool & Gym, A
2.0 star property
Santa Ana
2.0 out of 10, (1 review)
"You pay for a space in the apartment, it’s not the whole apartment be careful. The owner or whoever manages doesn’t give care about you as costumers they just want the money"
United States
Cristian Camilo Betancur
The price is ₹10,059
₹11,065 total
includes taxes & fees
21 Sept - 22 Sept
Room-sofa Bed Stay Rooftop Pool & Gym, A

9. Hotel San Felipe

Hotel San Felipe
4.0 star property
San Felipe, 0.7 km from Santa Ana
9.4 out of 10, Exceptional, (452 reviews)
"Everything was excellent"
United States
ORLANDO RICARDO
The price is ₹13,272
₹14,600 total
includes taxes & fees
21 Sept - 22 Sept
Hotel San Felipe

10. Central Hotel Panama Casco Viejo

Central Hotel Panama Casco Viejo
4.0 star property
San Felipe, 0.9 km from Santa Ana
9.0 out of 10, Wonderful, (1,005 reviews)
"Great location and nice hotel."
United States
Olga
The price is ₹17,584
₹19,342 total
includes taxes & fees
19 Oct - 20 Oct
Central Hotel Panama Casco Viejo

11. Hotel Riu Plaza Panama

Hotel Riu Plaza Panama
5.0 star property
Campo Alegre, 3.6 km from Santa Ana
9.0 out of 10, Wonderful, (5,964 reviews)
"Beautiful hotel, breakfast was wonderful, location was very convenient."
United States
Sandrelly
The price is ₹13,197
₹14,516 total
includes taxes & fees
28 Sept - 29 Sept
Hotel Riu Plaza Panama

12. Hotel Magnolia Boutique

Hotel Magnolia Boutique
2.0 star property
San Felipe, 0.7 km from Santa Ana
8.8 out of 10, Excellent, (517 reviews)
"Super nice hotel, very clean and location is amazing"
United States
Boris
The price is ₹6,853
₹7,539 total
includes taxes & fees
21 Sept - 22 Sept
Hotel Magnolia Boutique

13. Hotel Casa Panamá

Hotel Casa Panamá
4.0 star property
San Felipe, 0.6 km from Santa Ana
7.6 out of 10, Good, (757 reviews)
"Overall a good place to stay for exploring Panama. Lots of restaurants and activities walking distance."
United States
Naveera Jyoti
The price is ₹5,403
₹5,997 total
includes taxes & fees
21 Oct - 22 Oct
Hotel Casa Panamá

14. The Executive Hotel

The Executive Hotel
3.5 star property
Campo Alegre, 3.2 km from Santa Ana
9.2 out of 10, Wonderful, (1,260 reviews)
"great location, great hotel"
United States
Sandra
The price is ₹8,504
₹9,355 total
includes taxes & fees
7 Oct - 8 Oct
The Executive Hotel

15. Hotel Caribe

Hotel Caribe
3.0 star property
Calidonia, 1.2 km from Santa Ana
7.6 out of 10, Good, (336 reviews)
"Hotel clean and staff is great the facilities need a little updating there is no good bilingual help closed to everything my stay was great"
United States
dave
The price is ₹4,006
₹4,406 total
includes taxes & fees
30 Sept - 1 Oct
Hotel Caribe

16. Tantalo Hotel

Tantalo Hotel
3.5 star property
San Felipe, 0.7 km from Santa Ana
8.8 out of 10, Excellent, (333 reviews)
"Great location, friendly and helpful staff, very spacious room, very clean, Great breakfast because we could order straight from the in-house restaurant’s menu. Would definitely stay again."
United States
Cassondra
The price is ₹8,466
₹9,339 total
includes taxes & fees
4 Oct - 5 Oct
Tantalo Hotel

17. Plaza Paitilla Inn Hotel

Plaza Paitilla Inn Hotel
3.5 star property
Punta Paitilla, 3.4 km from Santa Ana
9.4 out of 10, Exceptional, (2,229 reviews)
"Great hotel, great location"
Canada
Catherine
The price is ₹9,901
₹10,891 total
includes taxes & fees
12 Oct - 13 Oct
Plaza Paitilla Inn Hotel

18. Sofitel Legend Casco Viejo, Panama City

Sofitel Legend Casco Viejo, Panama City
5.0 star property
San Felipe, 1.1 km from Santa Ana
9.8 out of 10, Exceptional, (749 reviews)
"Amazing service and beautiful hotel"
United States
Jose
The price is ₹34,084
₹37,492 total
includes taxes & fees
6 Oct - 7 Oct
Sofitel Legend Casco Viejo, Panama City

19. Oasis Hotel

Oasis Hotel
3.0 star property
San Felipe, 0.6 km from Santa Ana
8.6 out of 10, Excellent, (154 reviews)
"Great stay! Highly recommend"
United States
Gregg
The price is ₹5,353
₹5,923 total
includes taxes & fees
30 Sept - 1 Oct
Oasis Hotel

20. Principe Hotel and Suites

Principe Hotel and Suites
3.0 star property
El Cangrejo, 3.9 km from Santa Ana
9.0 out of 10, Wonderful, (2,062 reviews)
"Good area around for short time visit"
United States
Eliel
The price is ₹5,669
₹6,236 total
includes taxes & fees
21 Sept - 22 Sept
Principe Hotel and Suites
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Compare popular hotels in Santa Ana

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet-friendly
WiFi included
Outdoor pool, open 7:00 AM to 10:00 PM, pool umbrellas, pool loungers
Casco View Life Residences
4.0 star property
9.0
Wonderful
106 reviews
View
Interior
Hotel Caracas - Casco Viejo
3.0 star property
8.0
Very good
16 reviews
View
Bar (on property)
Hostal La Cigarra
2.0 star property
7.6
Good
73 reviews
View
Apartment (20) | Iron/ironing board, free WiFi, bed sheets
La Manzana Barrio Vivo by Wynwood
3.0 star property
7.6
Good
19 reviews
View
Double Room | View from room
Hotel República
2.0 star property
6.8
197 reviews
View

Where to stay in Santa Ana

Find the best Santa Ana areas for the activities you enjoy most.

Casco Viejo

Unique features of Casco Viejo include the historical sites and bars. Make a stop by Independence Square or Interoceanic Canal Museum while you're exploring the area.

Bella Vista

Travellers love Bella Vista for its popular shops, and you can see more of Panama City by jumping on the metro at Iglesia del Carmen Station or Vía Argentina Station. You might spend time checking out top sights like Via Espana and Iglesia del Carmen.

El Cangrejo

The ample dining options and casino gaming are top of the list for many visitors to El Cangrejo. A stop by Via Espana or Crown Casino might round out your trip.

San Francisco

San Francisco is noteworthy for its restaurants, and you can make a stop at top attractions like Multiplaza Pacific Mall and Calle 50.

San Felipe

While visiting San Felipe, you might make a stop by sights like Independence Square and Interoceanic Canal Museum.

Top Santa Ana Hotel Reviews

Find out more about Santa Ana

Top reasons to visit Santa Ana

  • Historic Landmarks: Santa Ana boasts significant attractions, including the historic Santa Ana Church and a nearby history museum, perfect for culture enthusiasts.
  • Engaging Walking Tours: Explore the area's rich culture and history through captivating walking tours available throughout Santa Ana and Panama City.
  • Vibrant Local Atmosphere: Experience the lively streets filled with friendly locals and the unique Panamanian vibes that characterise the neighbourhood.
  • Diverse Accommodation: Enjoy a variety of lodging options, from city-themed hotels to relaxing vacation rentals tailored to all travellers.
  • Family-Friendly Activities: Santa Ana is ideal for family vacations, offering shopping, outdoor adventures, and scenic views for all ages.

Find great hotels near Santa Ana

In Santa Ana, Panama, you'll discover a variety of accommodation options tailored to every traveller's needs, from city-themed hotels to comfortable apartments. Whether you seek a pet-friendly stay, a business-friendly environment, or a relaxing vacation rental, Santa Ana offers a diverse selection of hotels, including the renowned Hotel El Panama. Experience the charm of Panamá Province while enjoying convenient access to the city's attractions and amenities.

  • Central Hotel Panama Casco Viejo: Central Hotel Panama Casco Viejo is a charming 4-star hotel that boasts a guest rating of 9.2 out of 10. Located 805m from Santa Ana, this hotel offers a romantic and spa-themed retreat for couples seeking a serene escape. Guests can indulge in romance packages featuring amenities such as Champagne Service and 24-hour Room Service. The hotel's full spa offers a range of treatments including Body Treatments, Body Scrubs, and Massages, ensuring a relaxing experience. The inviting pool area complements the spa services, making it an ideal location for couples looking to unwind together.
  • American Trade Hotel: With a guest rating of 9.4 out of 10, the 4.5-star American Trade Hotel is situated just 644m from Santa Ana. This vibrant hotel caters to families and adventure seekers alike, offering nearby activities such as hiking, Segway tours, and bicycle rentals. Children are well taken care of with amenities like cribs and breakfast options. For those seeking romance, the hotel provides intimate dining experiences with beautiful garden views. Guests can also enjoy relaxing spa services and an outdoor pool, making it an excellent choice for those wanting both adventure and relaxation.
  • Sofitel Legend Casco Viejo, Panama City: A luxurious 5-star hotel, Sofitel Legend Casco Viejo has an impressive guest rating of 9.8 out of 10. Located 1km from Santa Ana, this hotel is ideal for discerning travellers seeking a spa-themed and business-friendly environment. The hotel features a comprehensive spa offering treatments like manicures, couples' treatment rooms, and a poolside bar. Guests can expect top-notch amenities and an elegant atmosphere, perfect for both relaxation and professional engagements.

Where to stay near Santa Ana

Santa Ana, nestled in Panamá Province, offers an inviting blend of family-friendly and business atmospheres, ideal for diverse travellers. Explore lively streets filled with friendly locals, vibrant culture, and unique Panamanian vibes. Nearby, you’ll find attractions that showcase the best of Panama, making it a perfect base for relaxation and luxury. Immerse yourself in this charming neighbourhood, where every corner reveals a new experience waiting to be discovered.

  • Panama City: As the vibrant heart of Panama, Panama City offers a rich blend of modernity and tradition. Situated in the province of Panamá, it serves as a hub for business and family tourism. The city sees a steady flow of visitors year-round, with peaks in January, July, and September. While exploring, you can indulge in shopping at various centres and malls, while nearby attractions like beaches and parks provide a refreshing escape. The lively streets are perfect for strolling, allowing you to soak in the eclectic atmosphere of this dynamic city.
  • Casco Viejo: A mere 644m from Santa Ana, Casco Viejo is a charming neighbourhood steeped in history. Known for its colonial architecture and cobblestone streets, this area attracts visitors year-round, especially during the bustling months of January and March to April. You’ll find a range of shopping areas and resorts, alongside picturesque parks and beaches that add to its allure. Casco Viejo is an ideal place for families and city explorers alike, offering a perfect mix of cultural experiences and leisure activities.
  • San Felipe: Also located just 644m from Santa Ana, San Felipe is another delightful neighbourhood that captures the essence of Panama’s rich heritage. Visitors flock here throughout the year, particularly in February to March and December. The area boasts various shopping options, resorts, and close proximity to beautiful parks and beaches. San Felipe is perfect for families looking for a blend of relaxation and adventure, making it a must-visit during your stay.

Things to do near Santa Ana

Shopping

Near the vibrant streets of Santa Ana, you’ll discover the bustling Mercado de Santa Ana, where you can find local crafts and delicious street food. For a more modern shopping experience, visit Albrook Mall, offering a variety of shops and entertainment options.

Recreation

The Serenity Spa offers a tranquil environment with a range of treatments including massages, facials, and wellness therapies. Enjoy lush gardens and soothing music as you unwind. For physical activity, the Santa Ana Park features scenic walking paths, ideal for leisurely strolls and connecting with nature.

Adventure

Gatun Eco Adventures offers an exhilarating zipline and ropes course experience located 48km from Santa Ana. Soar through the treetops while enjoying stunning views of the lush surroundings, and embrace the thrill of navigating through various obstacles that challenge your agility and courage.

Nightlife

Santa Ana's nightlife offers vibrant bars and local eateries, where you can enjoy live music and traditional Panamanian cuisine. For a lively atmosphere, visit Casa del Cerveza for craft beers or the stylish La Tana for wine and tapas. The streets buzz with energy, perfect for an evening stroll.

*Distances are measured in a straight line; actual driving distances may vary depending on the route.

Find the best attractions near Santa Ana

Santa Ana in Panama City offers a delightful blend of family-friendly, city-themed, and business vacations. Visitors can explore captivating attractions such as the local hill, the historic Santa Ana Church, and the nearby history museum. This vibrant area caters to those seeking cultural immersion, outdoor adventures, and scenic views, ensuring a rich experience for all travellers. Don't miss the chance to discover the charm of Santa Ana and its surroundings during your visit.

  • Metropolitan Cathedral of Panama: This stunning cathedral, located 805m from Santa Ana, stands as a testament to Panama's rich history and architectural beauty. Its intricate design and serene atmosphere invite visitors to appreciate the cultural significance and spiritual essence of this landmark.
  • Interoceanic Canal Museum: Situated 805m away, this museum offers a fascinating insight into the engineering marvel of the Panama Canal. Through engaging exhibits, visitors can explore the canal's history, its impact on global trade, and the cultures intertwined with its creation.
  • Independence Square: A vibrant piazza located 805m from Santa Ana, Independence Square serves as a hub of local life and culture. Surrounded by historic buildings, it provides a perfect setting for leisurely strolls while soaking up the lively atmosphere and the essence of Panamanian history.

Best time to go to Santa Ana

The best time to visit Santa Ana can depend on the weather and when visitor numbers rise and fall. The hottest average temperature around Santa Ana falls in April, when visitor numbers are average and weather is mostly sunny with light rain. The coolest average temperature around Santa Ana falls in November, visitor numbers are average and weather is mostly cloudy with frequent rain.

calendar iconCalendar Monthtemperature iconTemperaturerain iconPrecipitationmostly cloudy iconCloudinessoccupation rate iconOccupancyprice iconPricing
January78.8°F (26.0°C)No RainMostly SunnyAverageSlightly High
February79.2°F (26.2°C)No RainMostly SunnySlightly HighAverage
March79.7°F (26.5°C)No RainMostly SunnySlightly HighSlightly High
April80.4°F (26.9°C)Light RainMostly SunnyAverageSlightly High
May80.2°F (26.8°C)Frequent RainMostly CloudySlightly LowAverage
June79.9°F (26.6°C)Frequent RainMostly CloudySlightly LowAverage
July79.3°F (26.3°C)Frequent RainMostly CloudyAverageAverage
August79.2°F (26.2°C)Frequent RainMostly CloudyAverageAverage
September79.3°F (26.3°C)Frequent RainMostly CloudySlightly LowSlightly Low
October78.6°F (25.9°C)Frequent RainMostly CloudyAverageSlightly Low
November78.3°F (25.7°C)Frequent RainMostly CloudyAverageSlightly Low
December78.6°F (25.9°C)Light RainMostly CloudySlightly HighAverage

The nearest major airports for your trip to Santa Ana

Flying into Santa Ana, Panama, is convenient with three major airports nearby. Tocumen International Airport (PTY) is approximately 21km away, with luxurious hotels such as The Santa Maria and JW Marriott Panama offering shuttle services. Marcos A. Gelabert International Airport (PAC) is only 3km from Santa Ana, featuring top hotels like W Panama and Sofitel Legend Casco Viejo, both providing accessible transportation options. Balboa Airport (BLB) is situated 6km away, with hotels like The Westin Playa Bonita Panama and Bristol Panama, which also offer shuttle services. All these airports ensure easy access to Santa Ana for a delightful stay in Panama City.

Frequently asked questions

What's it like in Santa Ana?
Santa Ana is a neighbourhood that travellers like for its seafood restaurants, shopping and parks. Are you looking for Santa Ana travel tips? Make sure that you visit Avenida Balboa and El Machetazo Santa Ana while you're in the neighbourhood.
Where is the best hotel for a stay in Santa Ana?
Based on our traveller data, Hotel Caracas - Casco Viejo is one of the top choices for your stay in Santa Ana. This hotel is a short 7-minute walk from Avenida Balboa, and it offers a restaurant and a bar. Another good choice for your stay in the area is Casco View Life Residences.
How many hotels can I expect to find in Santa Ana?
Expedia has 134 hotels and other accommodation options in Santa Ana to choose from, making this an ideal home base for exploring the greater Panama City area.
If I need to cancel my hotel reservation in Santa Ana, will I receive a refund?
Yes! You'll find that most room reservations are fully refundable provided that you cancel before the accommodation's cancellation deadline, which is often 24 or 48 hours before check in. If you booked a non-refundable reservation, you may still be able to cancel and be given a refund within 24 hours of your booking. Enter your dates, click on "Search", then use the filter option "fully refundable" to view the best options available in Santa Ana.
What is there to do in this Panama City neighbourhood?
If you're looking forward to a day of shopping in Santa Ana, consider El Machetazo Santa Ana or Avenida Balboa, and pick out the perfect souvenir. When you're sightseeing in Panama City, Albrook Shopping Mall and Avenida Central are also worth a stop.

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