Search Hotels in Santa Ana, Panama City

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

This weekend
Next weekend

Filter by

Guest rating
Guest rating
Star rating

Our top choices for Santa Ana hotels

Hostal La Cigarra

Hostal La Cigarra
2.0 star property
Santa Ana
7.6 out of 10, Good, (70 reviews)
"Excellent staff, close to metro and embassies. A good location, good room for a great price. I would stay again. "
United Kingdom
Mark
The price is ₹2,559
₹2,853 total
includes taxes & fees
3 Jun - 4 Jun
Hostal La Cigarra

Casco View Apartments

Casco View Apartments
3.5 star property
Santa Ana
9.0 out of 10, Wonderful, (93 reviews)
"yes there was laundryroom, iron and nice pool. the stay was very good"
United States
melvin
The price is ₹7,946
₹11,579 total
includes taxes & fees
20 May - 21 May
Casco View Apartments

ART CASCO The Hotel

ART CASCO The Hotel
2.0 star property
Santa Ana
6.0 out of 10, (11 reviews)
"Walkable location and free secure parking! The price is really affordable, but the condition of the hotel is not the best"
United States
Eldris
The price is ₹3,052
₹3,403 total
includes taxes & fees
14 May - 15 May
ART CASCO The Hotel

Hotel República

Hotel República
2.0 star property
Santa Ana
6.8 out of 10, (192 reviews)
"It's meant for a short stay, close to Casco Viejo and coast line. Clean bed and bathroom. Needs some maintenance. Beware, there's no hot water if that's a deal breaker for you."
United States
Mario
The price is ₹2,352
₹2,629 total
includes taxes & fees
3 Jun - 4 Jun
Hotel República

La Manzana by Wynwood House

La Manzana by Wynwood House
3.0 star property
Santa Ana
7.4 out of 10, Good, (17 reviews)
"Very clean and safe property"
United States
Javier Alberto Lindauer
The price is ₹6,273
₹9,502 total
includes taxes & fees
10 May - 11 May
La Manzana by Wynwood House

Hotel Riazor

Hotel Riazor
3.0 star property
Santa Ana
3.8 out of 10, (11 reviews)
"Rough neighborhood "
Canada
Del
The price is ₹2,573
₹2,830 total
includes taxes & fees
12 May - 13 May
Hotel Riazor

Panama Canal Inn

Panama Canal Inn
3.0 star property
2.4 km from Santa Ana
8.2 out of 10, Very good, (20 reviews)
"Excellent hotel, good location, nice stay and great service."
United States
Rocio Hernandez
The price is ₹4,258
₹5,629 total
includes taxes & fees
8 May - 9 May
Panama Canal Inn

Crowne Plaza Panama Airport by IHG

Crowne Plaza Panama Airport by IHG
4.0 star property
21.1 km from Santa Ana
8.6 out of 10, Excellent, (2,516 reviews)
"Good place to stay while traveling."
United States
Annery
The price is ₹12,016
₹13,842 total
includes taxes & fees
17 May - 18 May
Crowne Plaza Panama Airport by IHG

Riande Aeropuerto Hotel & Casino

Riande Aeropuerto Hotel & Casino
4.0 star property
19.8 km from Santa Ana
8.4 out of 10, Very good, (1,843 reviews)
"Friendly staff."
Canada
Samuel
The price is ₹10,346
₹11,380 total
includes taxes & fees
21 May - 22 May
Riande Aeropuerto Hotel & Casino

ORHO Hotel Boutique 15 Minutes from PTY Airport

ORHO Hotel Boutique 15 Minutes from PTY Airport
2.0 star property
20.5 km from Santa Ana
8.8 out of 10, Excellent, (116 reviews)
"Great place to stay with plenty of places nearby for food and drinks"
United States
Thomas
The price is ₹10,752
₹13,955 total
includes taxes & fees
17 May - 18 May
ORHO Hotel Boutique 15 Minutes from PTY Airport

The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
5.0 star property
Juan Diaz, 12.7 km from Santa Ana
9.6 out of 10, Exceptional, (693 reviews)
"Breakfast was exceptional, everything you could think of was available. The spa was great and the staff 10/10"
United States
Aeon
The price is ₹23,513
₹25,864 total
includes taxes & fees
15 May - 16 May
The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

Arcadia Condo Suites

Arcadia Condo Suites
2.5 star property
Costa del Este, 10.2 km from Santa Ana
9.4 out of 10, Exceptional, (283 reviews)
"Very good place to stay and safe place..!"
United States
Somnueg
The price is ₹11,354
₹17,484 total
includes taxes & fees
10 May - 11 May
Arcadia Condo Suites

Villa Caprichosa

Villa Caprichosa
2.5 star property
18.3 km from Santa Ana
9.8 out of 10, Exceptional, (67 reviews)
"What a beautiful place! A dream come true. "
United States
Mariela
The price is ₹18,095
₹19,904 total
includes taxes & fees
12 May - 13 May
Villa Caprichosa

The Beach House

The Beach House
3.0 star property
Amador, 4.8 km from Santa Ana
8.4 out of 10, Very good, (432 reviews)
"Everting was clean and good nice place to stay "
United States
Kristine
The price is ₹7,038
₹7,742 total
includes taxes & fees
10 May - 11 May
The Beach House

The Westin Panama

The Westin Panama
4.0 star property
Costa del Este, 9.4 km from Santa Ana
9.0 out of 10, Wonderful, (332 reviews)
"Excellent stay, friendly and attentive staff, beautiful property!!!"
United States
Erica
The price is ₹21,888
₹24,076 total
includes taxes & fees
23 May - 24 May
The Westin Panama

Sofitel Legend Casco Viejo, Panama City

Sofitel Legend Casco Viejo, Panama City
5.0 star property
San Felipe, 1.1 km from Santa Ana
9.8 out of 10, Exceptional, (645 reviews)
"Had a lovely stay"
United States
Olly
The price is ₹29,159
₹32,075 total
includes taxes & fees
1 Jun - 2 Jun
Sofitel Legend Casco Viejo, Panama City

Hotel Riu Plaza Panama

Hotel Riu Plaza Panama
5.0 star property
Campo Alegre, 3.6 km from Santa Ana
9.0 out of 10, Wonderful, (5,399 reviews)
"Breakfast was super good and the staff super nice ,, very clean room "
United States
Marjoris
The price is ₹12,030
₹13,233 total
includes taxes & fees
4 Jun - 5 Jun
Hotel Riu Plaza Panama

Courtyard by Marriott Panama Metromall

Courtyard by Marriott Panama Metromall
4.0 star property
14.7 km from Santa Ana
9.0 out of 10, Wonderful, (1,007 reviews)
"Great service, very comfortable beds, truly excellent breakfast manager and staff. "
United States
Elizabeth
The price is ₹8,829
₹9,711 total
includes taxes & fees
23 May - 24 May
Courtyard by Marriott Panama Metromall

JW Marriott Panama

JW Marriott Panama
5.0 star property
Punta Pacifica, 4.3 km from Santa Ana
9.0 out of 10, Wonderful, (1,013 reviews)
"Very nice and safe place to stay"
United States
Nilesh
The price is ₹24,902
₹27,392 total
includes taxes & fees
5 Jun - 6 Jun
JW Marriott Panama

Sheraton Grand Panama

Sheraton Grand Panama
4.0 star property
San Francisco, 5.7 km from Santa Ana
8.6 out of 10, Excellent, (1,013 reviews)
"The staff were excellent!"
United States
James
The price is ₹12,688
₹13,956 total
includes taxes & fees
15 May - 16 May
Sheraton Grand Panama
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Compare popular hotels in Santa Ana

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet-friendly
WiFi included
Outdoor pool, open 7:00 AM to 10:00 PM, pool umbrellas, pool loungers
Casco View Apartments
3.5 star property
9.0
Wonderful
93 reviews
View
Bar (on property)
Hostal La Cigarra
2.0 star property
7.6
Good
70 reviews
View
Double Room | View from room
Hotel República
2.0 star property
6.8
192 reviews
View
Front of property
ART CASCO The Hotel
2.0 star property
6.0
11 reviews
View
Bar (on property)
Hotel Riazor
3.0 star property
3.8
11 reviews
View

Where to stay in Santa Ana

Find the best Santa Ana areas for the activities you enjoy most.

Casco Viejo

Unique features of Casco Viejo include the historical sites and bars. Make a stop by Independence Square or Interoceanic Canal Museum while you're exploring the area.

Bella Vista

Travellers love Bella Vista for its popular shops, and you can see more of Panama City by jumping on the metro at Iglesia del Carmen Station or Vía Argentina. You might spend time checking out top sights like Via Espana and Iglesia del Carmen.

El Cangrejo

The ample dining options and casino gaming are top of the list for many visitors to El Cangrejo. A stop by Via Espana or Crown Casino might round out your trip.

San Francisco

San Francisco is noteworthy for its restaurants, and you can make a stop at top attractions like Multiplaza Pacific Mall and Calle 50.

San Felipe

While visiting San Felipe, you might make a stop by sights like Independence Square and Interoceanic Canal Museum.

Top Santa Ana Hotel Reviews

Frequently asked questions

What's it like in Santa Ana?
Santa Ana is a neighbourhood that travellers like for its seafood restaurants, shopping and parks. Are you looking for Santa Ana travel tips? Make sure that you visit Avenida Balboa and El Machetazo Santa Ana while you're in the neighbourhood.
Where is the best hotel for a stay in Santa Ana?
Based on our traveller data, Casco View Apartments is one of the top choices for your stay in Santa Ana. This condo is a short 8-minute walk from Avenida Balboa, and it offers an outdoor pool and in-room kitchens.
How many hotels can I expect to find in Santa Ana?
Expedia has 120 hotels and other accommodation options in Santa Ana to choose from, making this an ideal home base for exploring the greater Panama City area.
If I need to cancel my hotel reservation in Santa Ana, will I receive a refund?
Yes! You'll find that most room reservations are fully refundable provided that you cancel before the accommodation's cancellation deadline, which is often 24 or 48 hours before check in. If you booked a non-refundable reservation, you may still be able to cancel and be given a refund within 24 hours of your booking. Enter your dates, click on "Search", then use the filter option "fully refundable" to view the best options available in Santa Ana.
What is there to do in this Panama City neighbourhood?
If you're looking forward to a day of shopping in Santa Ana, consider El Machetazo Santa Ana or Avenida Balboa, and pick out the perfect souvenir. When you're sightseeing in Panama City, Albrook Shopping Mall and Avenida Central are also worth a stop.

Explore a world of travel with Expedia