Photo by Hideki Yamagata
Search Adults Only Resorts & Hotels in San Francisco
Change your mind
Book hotels with free cancellation
Be picky
Search almost a million properties worldwide
Check availability on San Francisco Adults Only Resorts & Hotels
Tonight
Tomorrow
This weekend
Next weekend
Top San Francisco Adults Only Resorts & Hotels
Our top choices for San Francisco adults-only hotels
Tantalo Hotel
Tantalo Hotel
8.8 out of 10, Excellent, (270)
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Top San Francisco Hotel Reviews
Explore a world of travel with Expedia
Explore a world of travel with Expedia
Choose Your San Francisco Hotel Style
More accommodation types in San Francisco
Hotels near popular Panama City Attractions
Explore more hotels
- San Francisco by Wynwood House
- Hotel Riu Plaza Panama
- Dreams Playa Bonita Panama - All Inclusive
- Waymore Hotel Spa & Casino
- Crowne Plaza Panama Airport by IHG
- The Westin Playa Bonita Panama
- Principe Hotel and Suites
- The Executive Hotel
- Studio Coliving
- Hotel Costa Inn
- Novotel Panama City
- Marriott Panama Hotel
- Waldorf Astoria Panama
- AC Hotel by Marriott Panama City
- Hotel El Panama by Faranda Grand, a member of Radisson Individuals
- Riande Urban Hotel
- W Panama
- Hotel Ojos del Rio
- Sofitel Legend Casco Viejo, Panama City
- The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
Expedia's Latest Trends
Hotels
- Hotels in Bhiwadi
- ShangriLaHotelsandResorts Hotels in Mumbai
- Lemon Tree Hotel Jamnagar
- Hotels with Swimming Pool in Sasan Gir
- Sofitel Dubai Jumeirah Beach
- Kingston Suites Bangkok
- Hotels in Koilkuntla
- OYO Bailbrook Lodge, Bath
- Hotels in Salvador
- Hotel Landmark Royale
- Waldorf Astoria Kuwait
- Hotel Niharika
- Hotels near Howrah Belur Station
- Wedding Hotels in New Delhi
- Al Madina Hotel
- Hotels with Balcony in Kochi
- Hotels in Saket
- Hotels in Osian
Flights
Packages
