The Best Hotels Closest to Museum of Life and Science in Raleigh - 2026 Updated Prices

Our top choices for Museum of Life and Science hotels

Hampton Inn & Suites Durham/North I-85

1.4 km from Museum of Life and Science

Ed

₹12,914 total

includes taxes & fees

14 Jun - 15 Jun

Holiday Inn Express Durham by IHG

2.2 km from Museum of Life and Science

Kathy

₹12,322 total

includes taxes & fees

21 Jun - 22 Jun

Suite, 1 King Bed with Sofa bed, Non Smoking | Premium bedding, desk, blackout curtains, iron/ironing board

Comfort Inn & Suites Durham near Duke University

Croasdaile Farm Master, 3.2 km from Museum of Life and Science

Kathy

₹10,473 total

includes taxes & fees

1 Jun - 2 Jun

Red Roof Inn Durham - Duke Univ Medical Center

2.2 km from Museum of Life and Science

Derrick

₹7,165 total

includes taxes & fees

1 Jun - 2 Jun

Hampton Inn & Suites Durham University Medical Center

4.8 km from Museum of Life and Science

Curtis

₹12,490 total

includes taxes & fees

7 Jun - 8 Jun

Hilton Garden Inn Durham/University Medical Center

9th Street District, 3.3 km from Museum of Life and Science

Susan

₹15,864 total

includes taxes & fees

14 Jun - 15 Jun

Washington Duke Inn & Golf Club

5.9 km from Museum of Life and Science

Jessica

₹21,400 total

includes taxes & fees

31 May - 1 Jun

Residence Inn Durham McPherson/Duke University Medical Cntr

Trinity Park, 3.3 km from Museum of Life and Science

Tiffany

₹17,976 total

includes taxes & fees

29 May - 30 May

JB Duke Hotel

5.6 km from Museum of Life and Science

Andrew

₹21,509 total

includes taxes & fees

27 May - 28 May

SpringHill Suites by Marriott Durham City View

4.6 km from Museum of Life and Science

Evelyn

₹13,413 total

includes taxes & fees

31 May - 1 Jun

University Inn Durham next to Duke University Medical Center

4 km from Museum of Life and Science

Thomas

₹11,318 total

includes taxes & fees

29 May - 30 May

The Durham Hotel

Downtown Durham, 3.6 km from Museum of Life and Science

George

₹20,105 total

includes taxes & fees

7 Jun - 8 Jun

Aloft by Marriott Durham Downtown

American Tobacco District, 4 km from Museum of Life and Science

Lucas

₹21,941 total

includes taxes & fees

21 Jun - 22 Jun

The Lodge at Duke Medical Center

4 km from Museum of Life and Science

Tracy

₹15,097 total

includes taxes & fees

6 Jun - 7 Jun

Hilton Durham near Duke University

5.2 km from Museum of Life and Science

Mary

₹12,770 total

includes taxes & fees

1 Jun - 2 Jun

Rizzo Center, a Destination by Hyatt Hotel

16.3 km from Museum of Life and Science

Jasmine

₹20,644 total

includes taxes & fees

3 Jun - 4 Jun

Hyatt Place Durham Southpoint

15.3 km from Museum of Life and Science

Donna

₹14,591 total

includes taxes & fees

1 Jun - 2 Jun

DoubleTree Suites by Hilton Raleigh - Durham

13.3 km from Museum of Life and Science

Patricia

₹10,678 total

includes taxes & fees

19 Jun - 20 Jun

The Colonial Inn, an Ascend Collection Hotel

18.9 km from Museum of Life and Science

Marcia

₹14,678 total

includes taxes & fees

15 Jun - 16 Jun

SpringHill Suites by Marriott Durham Chapel Hill

12 km from Museum of Life and Science

Wesley

₹12,827 total

includes taxes & fees

7 Jun - 8 Jun

View all properties

Compare popular hotels close to Museum of Life and Science

Property	Property class	Guest rating
Hampton Inn & Suites Durham/North I-85	2.5 star property	9.0 Wonderful 1,006 reviews	View
Holiday Inn Express Durham by IHG	2.5 star property	8.8 Excellent 1,004 reviews	View
Comfort Inn & Suites Durham near Duke University	2.5 star property	8.6 Excellent 1,013 reviews	View
Red Roof Inn Durham - Duke Univ Medical Center	2.0 star property	6.8 1,005 reviews	View
Hampton Inn & Suites Durham University Medical Center	2.5 star property	9.6 Exceptional 481 reviews	View

Top Museum of Life and Science Hotel Reviews

21c Museum Hotel Durham

10/10 Excellent

"Our room was beautifully appointed and so comfortable. We loved visiting the museum during our stay. Wonderful hotel!"

Red Roof Inn Durham - Duke Univ Medical Center

8/10 Good

"The stay was better than the last time, the room I had was more up to date. The only issue I had was I had to pay a 50.00 deposit when I arrived to the hotel. I prepaid for the room in advance and he said it was for a smoking deposit. I just stayed there a few weeks ago and didn’t pay a deposit. I don’t smoke but it should’ve been said online when booking the room and not told at the time of check in. I stayed 2 nights and housekeeping did come knock on my door to bring fresh linen if needed. It was a sign in the lobby saying I’d you needed them to come into your room let the front desk know by 10am which was a good thing for those who didn’t want to be disturbed."

Courtyard Durham Near Duke University/Downtown

8/10 Good

"It was a great experience especially from the staff. The barista was exceptionally pleasant and warm hearted each morning. The only complaint I would have was in regard to our bedsheets not being changed daily. Otherwise, we really enjoyed our short stay and look forward to coming back soon!"

The Durham Hotel

10/10 Excellent

"Great hotel, perfect location, close to the farmer’s market, downtown Durham, easy 20 min drive from the airport. Quiet, clean rooms. Excellent front desk person who went above and beyond to make sure to make us feel welcome. Free covered public parking during the week-end days. Not the first time we stay there and it will not be the last one! Thanks!"

Hilton Garden Inn Durham/University Medical Center

10/10 Excellent

"I found the hotel staff to be very courteous and professional. I have stayed at this hotel during three separate trips to Durham. The staff has always been wonderful to me. My hotel room was always clean and immaculate. The breakfasts were scrumptious."

Hotels near other Museum of Life and Science attractions

Brightleaf Square

4.8/5 (8 reviews)

You can do some window-shopping at Brightleaf Square during your visit to Durham. Discover the lively festivals and stunning cathedral in this family-friendly area.

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Frequently asked questions

What's the area like around Museum of Life and Science?

Museum of Life and Science is located in an area of Durham known for its stunning cathedral. If you're looking for a convenient place to stay, take a look at the 11 hotels and other accommodation options you'll find within a mile.

What's the best hotel to stay near Museum of Life and Science?

Hampton Inn & Suites Durham/North I-85 is one of the top choices for your stay based on our traveller data, and this hotel offers free breakfast and an indoor pool. It's located just a short 0.8 mi (1.4 km) from Museum of Life and Science. Other good options within 5 miles include Holiday Inn Express Durham by IHG and Courtyard Durham Near Duke University/Downtown.

How many hotels can I expect to find close to Museum of Life and Science?

Expedia has 11 hotels and other accommodation options within a mile from Museum of Life and Science.

If I need to cancel the hotel reservation for my stay near Museum of Life and Science, will I receive a refund?

Yes, the majority of hotel room reservations are fully refundable if cancelled prior to the accommodation's cancellation deadline, which often is within 24-48 hours of your scheduled arrival. If you have a non-refundable reservation, it may still be possible to cancel it and get a refund within 24 hours of your booking. Enter dates in and click on "Search", then use the filter option "fully refundable" to get the best deals near Museum of Life and Science.

What can I see and do near Museum of Life and Science?

You'll want to browse the exhibits at Nasher Museum of Art at Duke University and Bennett Place. Explore landmarks like American Tobacco Campus, Cameron Indoor Stadium and Black Wall Street. You can enjoy live performances at Carolina Theatre and Common Ground Theatre.

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Our top choices for Museum of Life and Science hotels

Hampton Inn & Suites Durham/North I-85

Holiday Inn Express Durham by IHG

Comfort Inn & Suites Durham near Duke University

Red Roof Inn Durham - Duke Univ Medical Center

Hampton Inn & Suites Durham University Medical Center

Hilton Garden Inn Durham/University Medical Center

Washington Duke Inn & Golf Club

Residence Inn Durham McPherson/Duke University Medical Cntr

JB Duke Hotel

SpringHill Suites by Marriott Durham City View

University Inn Durham next to Duke University Medical Center

The Durham Hotel

Aloft by Marriott Durham Downtown

The Lodge at Duke Medical Center

Hilton Durham near Duke University

Rizzo Center, a Destination by Hyatt Hotel

Hyatt Place Durham Southpoint

DoubleTree Suites by Hilton Raleigh - Durham

The Colonial Inn, an Ascend Collection Hotel

SpringHill Suites by Marriott Durham Chapel Hill

Compare popular hotels close to Museum of Life and Science

Top Museum of Life and Science Hotel Reviews

21c Museum Hotel Durham

Hotels near other Museum of Life and Science attractions

Brightleaf Square

Frequently asked questions