What is Midtown like?

Travellers are sure to enjoy a stay in St. Louis's Midtown neighbourhood. Make sure that you visit Chaifetz Arena and Scott Joplin House State Historic Site as part of your Midtown travel plans.

Where is the best place to stay in Midtown?

Based on our traveller data, Element by Marriott St. Louis Midtown is one of the top choices for your stay in Midtown. This hotel is a short 6-minute walk from St. Louis University, and it offers free breakfast and an indoor pool. Another good choice for your stay in the neighbourhood is Residence Inn by Marriott St Louis Downtown .

How many hotels will I be able to find in the Midtown area?

If you're searching for places to stay in St. Louis, Expedia has something to meet your needs with 35 Midtown hotels and other accommodation options to choose from.

If I need to cancel my hotel reservation in Midtown, will I receive a refund?

Yes! Most hotel room reservations are refundable if you cancel before the hotel’s cancellation deadline, which often is within 24-48 hours of check in. If you have a non-refundable reservation, it might still be possible to cancel it and receive a refund within 24 hours of booking. Add dates, click "Search", then use the filter option "fully refundable" to get top deals in Midtown.

What are the top things to see and do in Midtown?

Sights like Scott Joplin House State Historic Site, Red Flag and Museum of Contemporary Religious Art can be part of your cultural tour of Midtown. Chaifetz Arena and Washington Avenue Historic District are also a couple of places to visit in the neighbourhood. Favourite places to visit in the surrounding area include St. Louis Union Station, Busch Stadium and Dome at America’s Center. While you're out sightseeing, Gateway Arch and .ZACK Theater are a couple of additional sights to visit in St. Louis.

How can I get around Midtown and the greater St. Louis area?

Ready to get out and explore the city? Grand Station is the closest metro station.

The Best Hotels in Midtown, St. Louis - 2026 Updated Prices

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Our top choices for Midtown hotels

1. Element by Marriott St. Louis Midtown

Midtown

Brittany

₹15,137 total

includes taxes & fees

16 Aug - 17 Aug

2. Residence Inn by Marriott St Louis Downtown

Midtown

Jose

₹13,457 total

includes taxes & fees

13 Aug - 14 Aug

3. Fairfield Inn & Suites by Marriott St. Louis Downtown

Downtown West, 1.3 km from Midtown

Shelly

₹15,308 total

includes taxes & fees

3 Aug - 4 Aug

4. Angad Arts Hotel St. Louis, Tapestry Collection by Hilton

0.8 km from Midtown

Corey

₹12,208 total

includes taxes & fees

26 Aug - 27 Aug

5. Pear Tree Inn St. Louis Near Union Station

Downtown West, 1.2 km from Midtown

Olga

₹15,134 total

includes taxes & fees

3 Aug - 4 Aug

6. Courtyard by Marriott St. Louis Downtown West

Downtown West, 1.1 km from Midtown

₹13,791 total

includes taxes & fees

9 Aug - 10 Aug

7. Drury Plaza Hotel St. Louis Union Station

Downtown West, 1.5 km from Midtown

Shontrella

₹19,955 total

includes taxes & fees

3 Aug - 4 Aug

8. Hampton Inn & Suites St. Louis at Forest Park

Dogtown, 4.8 km from Midtown

Krystina

₹15,671 total

includes taxes & fees

9 Aug - 10 Aug

9. Hyatt Regency St. Louis at The Arch

Downtown St. Louis, 3.4 km from Midtown

Richard

₹17,200 total

includes taxes & fees

4 Aug - 5 Aug

10. Drury Plaza Hotel St. Louis at the Arch

Downtown St. Louis, 3.4 km from Midtown

Daniel

₹19,059 total

includes taxes & fees

3 Aug - 4 Aug

11. Aloft by Marriott St. Louis Cortex

Central West End, 2.2 km from Midtown

Khristina

₹12,771 total

includes taxes & fees

5 Aug - 6 Aug

12. Embassy Suites by Hilton St. Louis Downtown

Downtown St. Louis, 3.1 km from Midtown

Coranell

₹13,934 total

includes taxes & fees

16 Aug - 17 Aug

13. St. Louis Union Station Hotel, Curio Collection by Hilton

Downtown West, 1.7 km from Midtown

Sanela

₹16,926 total

includes taxes & fees

17 Aug - 18 Aug

14. 21C Museum Hotel St Louis

Downtown West, 2.1 km from Midtown

Seth

₹16,586 total

includes taxes & fees

23 Aug - 24 Aug

15. Tru By Hilton St. Louis Downtown

Downtown West, 2.5 km from Midtown

joseph

₹10,022 total

includes taxes & fees

25 Aug - 26 Aug

16. Live by Loews - St.Louis

Downtown St. Louis, 3 km from Midtown

Cindy

₹18,133 total

includes taxes & fees

3 Aug - 4 Aug

17. Home2 Suites by Hilton St. Louis/Forest Park

The Grove, 3 km from Midtown

paullita jeanne

₹15,694 total

includes taxes & fees

24 Aug - 25 Aug

Indoor pool, open 6:00 AM to 10:00 PM, pool loungers

18. Hampton Inn St. Louis-Downtown (At the Gateway Arch)

Downtown St. Louis, 3.5 km from Midtown

Kimberly A

₹13,699 total

includes taxes & fees

17 Aug - 18 Aug

19. Courtyard by Marriott St. Louis Downtown/Convention Center

Downtown St. Louis, 2.9 km from Midtown

Madison

₹12,020 total

includes taxes & fees

13 Aug - 14 Aug

20. Hotel Indigo St Louis - Central West End by IHG

Central West End, 3.2 km from Midtown

Morgan

₹14,773 total

includes taxes & fees

16 Aug - 17 Aug

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Where to stay in Midtown

Find the best Midtown areas for the activities you enjoy most.

The Gateway Arch in St. Louis, Missouri, with a well-maintained lawn and trees in the foreground.

Downtown St. Louis

Gourmet restaurants beloved sports teams and top sights from Gateway Arch to Busch Stadium – discover Downtown St. Louis, a destination also famous for its historic sites.

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A gazebo by a calm pond with autumn foliage and clear skies.

Clayton

Take time in Clayton to visit attractions like Chapel of St. Timothy And St. Titus, Concordia Seminary and Shaw Park Tennis Center. You might also appreciate the abundant dining options, and you can hop on the metro at Clayton Station to see more of the city.

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An ornate hall with arched ceilings and intricate patterns.

Downtown West

While visiting Downtown West, you might make a stop by sights like St. Louis Union Station and St. Louis Aquarium at Union Station.

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A modern building with a brick facade, parked cars, and a flower bed with tulips.

Central West End

Enjoy this relaxed area, the ultimate destination for a lazy afternoon. Browse unique stores, admire artworks and sip coffee at sidewalk tables shaded by trees.

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A lake with a curved shoreline, a parking lot, and a forested area with autumn foliage.

Creve Coeur

Travellers come to Creve Coeur for its abundant dining options, and you can see top attractions like Creve Coeur Golf Club and Skip Viragh Center for the Arts while you're in town.

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Top Midtown Hotel Reviews

Drury Plaza Hotel St. Louis at the Arch

10/10 Excellent

"The room was excellent. The beds were very comfortable. All the staff were so friendly and helpful above and beyond of what I'm used to! The complimentary drinks and snacks we're so nice that we didn't have to buy dinner!"

Drury Plaza Hotel St. Louis Union Station

10/10 Excellent

"While I have never stayed in a bad Drury, this one has to be the best one yet! The location is great!! Walking distance to much of the great things we wanted to see in St. Louis. The hotel is very clean. The staff is very friendly. The architecture is beautiful!! The bed was very comfortable and the room actually stayed at the cool temperature we set it to, making it a very comfortable nights sleep! We will definitely be back!!"

Marriott St. Louis Grand

8/10 Good

"Room was clean and updated but needed an exhaust fan in the bathroom. Paint was peeling in some areas from the moisture. AC was very loud when it turned on and off and woke me up throughout the night. Within walking distance of Busch Stadium. Staff was there when the Cardinals game let out to help load elevators quickly. Parking garage was a block away, but it wasn’t too much of a walk. Overall, it was a decent stay for catching a Cardinals game."

Search Hotels in Midtown, St. Louis

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Our top choices for Midtown hotels

1. Element by Marriott St. Louis Midtown

2. Residence Inn by Marriott St Louis Downtown

3. Fairfield Inn & Suites by Marriott St. Louis Downtown

4. Angad Arts Hotel St. Louis, Tapestry Collection by Hilton

5. Pear Tree Inn St. Louis Near Union Station

6. Courtyard by Marriott St. Louis Downtown West

7. Drury Plaza Hotel St. Louis Union Station

8. Hampton Inn & Suites St. Louis at Forest Park

9. Hyatt Regency St. Louis at The Arch

10. Drury Plaza Hotel St. Louis at the Arch

11. Aloft by Marriott St. Louis Cortex

12. Embassy Suites by Hilton St. Louis Downtown

13. St. Louis Union Station Hotel, Curio Collection by Hilton

14. 21C Museum Hotel St Louis

15. Tru By Hilton St. Louis Downtown

16. Live by Loews - St.Louis

17. Home2 Suites by Hilton St. Louis/Forest Park

18. Hampton Inn St. Louis-Downtown (At the Gateway Arch)

19. Courtyard by Marriott St. Louis Downtown/Convention Center

20. Hotel Indigo St Louis - Central West End by IHG

Where to stay in Midtown

Downtown St. Louis

Clayton

Downtown West

Central West End

Creve Coeur

Top Midtown Hotel Reviews

Drury Plaza Hotel St. Louis at the Arch

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