The Best Hotels Closest to Louisville Science Center in Louisville - 2026 Updated Prices

Q: What's the area like around Louisville Science Center?

Louisville Science Center is located in an area of Louisville known for its stunning river views, sporting events and great live music scene. If you're looking for a convenient place to stay, take a look at the 292 hotels and other accommodation options you'll find within a mile.

Q: Where is the best place to stay near Louisville Science Center?

Adjacent to Louisville Science Center, Holiday Inn Express & Suites Louisville Downtown by IHG is one of the top choices for your stay based on our traveller data, and this hotel offers free breakfast and a 24-hour fitness centre. Other good choices within a short distance include Galt House Hotel Trademark Collection by Wyndham and Omni Louisville Hotel .

Q: How many hotels can I expect to find close to Louisville Science Center?

Expedia has 292 hotels and other accommodation options within a mile from Louisville Science Center.

Q: If I need to cancel the hotel reservation for my stay near Louisville Science Center, will I receive a refund?

Yes! Most hotel room reservations are fully refundable as long as you cancel before the hotel’s cancellation deadline, which is usually within 24-48 hours of check in. If you booked a non-refundable reservation, you might be able to still cancel and get a refund within a 24-hour period of booking. Add dates, click "Search", then use the filter option "fully refundable" to get the top deals on offer near Louisville Science Center.

Q: What can I see and do near Louisville Science Center?

21c Museum Hotel, Louisville Slugger Museum and Muhammad Ali Center feature a variety of fascinating exhibits to see while you're in town. Explore landmarks like Belle of Louisville, Whiskey Row and Big Four Bridge. You can catch a show at Louisville Palace, Derby Dinner Playhouse and Headliners Music Hall.

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Our top choices for Kentucky Science Center hotels

An outdoor patio area with round tables and chairs, surrounded by potted plants and a brick chimney.

1. Market Street Inn

2.1 km from Kentucky Science Center

"Such a lovely stay at the Market Street Inn. A very charming, comfortable and feels like home kind of place. Carol and Steve are just the kindest owners. They were responsive and accommodating and always available if needed. We also loved meeting Lisa, who made breakfast each morning and took care of any housekeeping needs. We felt like we were treated as family and not just guests. The area and location is perfect, SUCH a cute little town. Plenty of restaurants, shops and entertainment within...

Ryan

₹23,551 total

includes taxes & fees

15 Nov - 16 Nov

A restaurant with a high ceiling, exposed brick walls, hanging plants, and a variety of seating arrangements.

2. Hotel Distil, Autograph Collection

Downtown Louisville, 0.9 km from Kentucky Science Center

Athina

₹22,298 total

includes taxes & fees

26 Nov - 27 Nov

A grand lobby with ornate columns, plush seating, and a chandelier.

3. The Brown Hotel

Downtown Louisville, 1.2 km from Kentucky Science Center

Brianne

₹11,793 total

includes taxes & fees

26 Nov - 27 Nov

An outdoor patio area with seating, a fire pit, and a pergola with string lights.

4. Homewood Suites by Hilton Louisville Downtown, KY

Downtown Louisville, 0.2 km from Kentucky Science Center

Jeanette

₹12,612 total

includes taxes & fees

24 Nov - 25 Nov

A modern interior with leather sofas, a bookshelf, and a decorative wall with 'The Grady' sign.

5. The Grady

Downtown Louisville, 0.2 km from Kentucky Science Center

Greg

₹16,445 total

includes taxes & fees

23 Nov - 24 Nov

A historic building with a grand entrance, steps leading up to the door, and a sign indicating it is a bed and breakfast.

6. DuPont Mansion Bed & Breakfast

Old Louisville, 2.8 km from Kentucky Science Center

Chris

₹19,927 total

includes taxes & fees

15 Nov - 16 Nov

An outdoor terrace with tables and chairs, large windows, and a view of the city skyline at sunset.

7. Tempo By Hilton Louisville Downtown Nulu

Phoenix Hill, 2.1 km from Kentucky Science Center

Addison

₹11,251 total

includes taxes & fees

25 Nov - 26 Nov

A modern building with a sign for "Stellar Suites."

8. Stellar Suites

East Market District, 2.2 km from Kentucky Science Center

Kevin

₹16,847 total

includes taxes & fees

19 Nov - 20 Nov

A rooftop bar with outdoor seating, including sofas and chairs, and a bar area with a television screen.

9. Omni Louisville Hotel

Downtown Louisville, 0.8 km from Kentucky Science Center

James

₹19,674 total

includes taxes & fees

22 Nov - 23 Nov

10. 21c Museum Hotel Louisville

Downtown Louisville, < 0.1 km from Kentucky Science Center

Erick

₹17,305 total

includes taxes & fees

6 Dec - 7 Dec

A hotel with a prominent sign, a central courtyard with a sculpture, and a dome structure in the background.

11. Hotel Bourré Bonne Louisville, Curio Collection by Hilton

Downtown Louisville, 0.8 km from Kentucky Science Center

Paul

₹16,279 total

includes taxes & fees

30 Nov - 1 Dec

A horse statue with a plaque in a modern interior space with a dining area and large windows.

12. Cambria Hotel Louisville Downtown-Whiskey Row

Downtown Louisville, 1.2 km from Kentucky Science Center

Trista

₹10,534 total

includes taxes & fees

13 Dec - 14 Dec

A modern lounge area with seating, tables, and a view of the city through large windows.

13. Towneplace Suites By Marriott Louisville Downtown

Downtown Louisville, 0.3 km from Kentucky Science Center

Brandi

₹10,757 total

includes taxes & fees

29 Nov - 30 Nov

A covered patio with a stone wall, a glass table, and a bench.

14. Central Park Bed & Breakfast

Old Louisville, 3 km from Kentucky Science Center

Stephen

₹17,895 total

includes taxes & fees

19 Nov - 20 Nov

A cozy living room with a fireplace, a black leather sofa, and a patterned rug.

15. Moxy Louisville Downtown

Downtown Louisville, 0.9 km from Kentucky Science Center

Priscilla

₹12,282 total

includes taxes & fees

14 Dec - 15 Dec

A bar with multiple shelves of liquor bottles and glasses.

16. Aloft by Marriott Louisville Downtown

Downtown Louisville, 0.9 km from Kentucky Science Center

Anthony

₹13,535 total

includes taxes & fees

25 Nov - 26 Nov

A bar area with a neon sign, red seating, and a bar counter.

17. Hotel Genevieve part of JdV by Hyatt

East Market District, 2.1 km from Kentucky Science Center

Brittney

₹15,834 total

includes taxes & fees

22 Nov - 23 Nov

A modern hotel lobby with a reception desk, seating area, and a large window providing natural light.

18. AC Hotel Louisville Downtown

East Market District, 2.1 km from Kentucky Science Center

Kevin

₹15,834 total

includes taxes & fees

27 Nov - 28 Nov

A modern interior with large windows offering a city view, a circular light fixture, and leather seating.

19. Galt House Hotel Trademark Collection by Wyndham

Downtown Louisville, 0.5 km from Kentucky Science Center

Shun

₹14,336 total

includes taxes & fees

23 Nov - 24 Nov

A building with a sign reading "Embassy Suites."

20. Embassy Suites Louisville Downtown

Downtown Louisville, 0.8 km from Kentucky Science Center

Ernest P

₹13,519 total

includes taxes & fees

22 Nov - 23 Nov

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Compare top hotels near Kentucky Science Center

Market Street Inn 3.5 star property 2.1 km from Kentucky Science Center View	Hotel Distil, Autograph Collection 4.0 star property Downtown Louisville, 0.9 km from Kentucky Science Center View	The Brown Hotel 4.5 star property Downtown Louisville, 1.2 km from Kentucky Science Center View	Homewood Suites by Hilton Louisville Downtown, KY 3.0 star property Downtown Louisville, 0.2 km from Kentucky Science Center View	The Grady 4.0 star property Downtown Louisville, 0.2 km from Kentucky Science Center View
9.8 Exceptional 127 reviews	9.6 Exceptional 520 reviews	9.4 Exceptional 1,482 reviews	9.4 Exceptional 1,004 reviews	9.4 Exceptional 1,003 reviews
The price is ₹20,841 ₹23,551 total includes taxes & fees 15 Nov - 16 Nov	The price is ₹18,951 ₹22,298 total includes taxes & fees 26 Nov - 27 Nov	The price is ₹10,023 ₹11,793 total includes taxes & fees 26 Nov - 27 Nov	The price is ₹10,719 ₹12,612 total includes taxes & fees 24 Nov - 25 Nov	The price is ₹13,976 ₹16,445 total includes taxes & fees 23 Nov - 24 Nov
Yes, Breakfast included No Pool No Spa No Pet-friendly Yes, WiFi included Yes, Parking	No Breakfast included No Pool No Spa Yes, Pet-friendly Yes, WiFi included Yes, Parking	No Breakfast included No Pool No Spa No Pet-friendly Yes, WiFi included Yes, Parking	Yes, Breakfast included Yes, Pool No Spa Yes, Pet-friendly Yes, WiFi included Yes, Parking	No Breakfast included No Pool No Spa Yes, Pet-friendly Yes, WiFi included Yes, Parking

Top Louisville Science Center Hotel Reviews

Embassy Suites Louisville Downtown

8/10 Good

"Added cost at checkin for $100 a day was not mentioned and wouldn't have been nice to know. You have to do valet if you drive parking is extremely minimal."

Homewood Suites by Hilton Louisville Downtown, KY

10/10 Excellent

"This was one of the best moderate price hotels in which we’ve ever stayed. The hotel was beautifully decorated; room was spacious and comfortable; staff were great and breakfast was exceptional with a huge variety with lots of toppings and touches. Location was perfect as well for our downtown walking exploration."

Holiday Inn Louisville Downtown by IHG

10/10 Excellent

"Property was clean and well kept. The valet parking did not make much sense to me though. I do not mind valeting my car and always opt to do so when traveling out of town if needed. However, most valet lots are private from public parking where the cars are not easily accessible. Here the valet lot is essentially an open lot I could have parked my car in on my own. Adding to this anybody could have gotten to or from our car at any point and time. Most nights we ended up parking our cars ourselves and then turning the keys over to the valet drivers, and the same thing when we needed to leave in the morning, we retrieved our keys from the valet driver and went and got out own vehicles, again entirely defeating the purpose of valet parking. Other than the parking there are no complaints about our stay."

Towneplace Suites By Marriott Louisville Downtown

8/10 Good

"Check in and check out we’re a breeze. The front desk staff was very helpful and knowledgeable. Breakfast selection was great and hot tea and coffee hot cocoa always was available in the lobby. Close walk to slugger museum and bourbon tours. Parking is $24 a night but close by and secured. Will def stay here again!"

Other attractions near Kentucky Science Center

A tall wooden baseball bat leaning against a brick building with a sign reading "Hillerich & Brassler Co."

Louisville Slugger Museum

9.2/10 (2,299 reviews)

Baseball is part of the American fabric. See where one important tool for this sport is produced in the factory that makes ball games possible.

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Frequently asked questions

What's the area like around Louisville Science Center?

Louisville Science Center is located in an area of Louisville known for its stunning river views, sporting events and great live music scene. If you're looking for a convenient place to stay, take a look at the 292 hotels and other accommodation options you'll find within a mile.

Where is the best place to stay near Louisville Science Center?

Adjacent to Louisville Science Center, Holiday Inn Express & Suites Louisville Downtown by IHG is one of the top choices for your stay based on our traveller data, and this hotel offers free breakfast and a 24-hour fitness centre. Other good choices within a short distance include Galt House Hotel Trademark Collection by Wyndham and Omni Louisville Hotel.

How many hotels can I expect to find close to Louisville Science Center?

Expedia has 292 hotels and other accommodation options within a mile from Louisville Science Center.

If I need to cancel the hotel reservation for my stay near Louisville Science Center, will I receive a refund?

Yes! Most hotel room reservations are fully refundable as long as you cancel before the hotel's cancellation deadline, which is usually within 24-48 hours of check in. If you booked a non-refundable reservation, you might be able to still cancel and get a refund within a 24-hour period of booking. Add dates, click "Search", then use the filter option "fully refundable" to get the top deals on offer near Louisville Science Center.

What can I see and do near Louisville Science Center?

21c Museum Hotel, Louisville Slugger Museum and Muhammad Ali Center feature a variety of fascinating exhibits to see while you're in town. Explore landmarks like Belle of Louisville, Whiskey Row and Big Four Bridge. You can catch a show at Louisville Palace, Derby Dinner Playhouse and Headliners Music Hall.

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Our top choices for Kentucky Science Center hotels

1. Market Street Inn

2. Hotel Distil, Autograph Collection

3. The Brown Hotel

4. Homewood Suites by Hilton Louisville Downtown, KY

5. The Grady

6. DuPont Mansion Bed & Breakfast

7. Tempo By Hilton Louisville Downtown Nulu

8. Stellar Suites

9. Omni Louisville Hotel

10. 21c Museum Hotel Louisville

11. Hotel Bourré Bonne Louisville, Curio Collection by Hilton

12. Cambria Hotel Louisville Downtown-Whiskey Row

13. Towneplace Suites By Marriott Louisville Downtown

14. Central Park Bed & Breakfast

15. Moxy Louisville Downtown

16. Aloft by Marriott Louisville Downtown

17. Hotel Genevieve part of JdV by Hyatt

18. AC Hotel Louisville Downtown

19. Galt House Hotel Trademark Collection by Wyndham

20. Embassy Suites Louisville Downtown

Compare top hotels near Kentucky Science Center

Market Street Inn

Hotel Distil, Autograph Collection

The Brown Hotel

Homewood Suites by Hilton Louisville Downtown, KY

The Grady

Top Louisville Science Center Hotel Reviews

Embassy Suites Louisville Downtown

Other attractions near Kentucky Science Center

Louisville Slugger Museum

Frequently asked questions

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