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25 Sept - 27 Sept
Next weekend
2 Oct - 4 Oct

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Our top choices for Isle of Palms hotels

A spacious living area with a high ceiling, a fireplace, and a bar area in the background.

1. Residence Inn By Marriott Jacksonville - Mayo Clinic Area

Residence Inn By Marriott Jacksonville - Mayo Clinic Area
3.0 star property
Isle of Palms
9.4 out of 10, Exceptional, (602 reviews)
"Great stay"
United States
Michaelanne
The price is ₹14,491
₹16,447 total
includes taxes & fees
23 Oct - 24 Oct
Residence Inn By Marriott Jacksonville - Mayo Clinic Area
A lobby with a reception desk, seating area, and a staircase.

2. Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area by IHG

Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area by IHG
2.5 star property
3.9 km from Isle of Palms
9.0 out of 10, Wonderful, (1,006 reviews)
"wonderful breakfast and friendly staff"
United States
frances
The price is ₹9,655
₹10,958 total
includes taxes & fees
18 Oct - 19 Oct
Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area by IHG
An outdoor seating area with a fire pit, wicker furniture, and a covered patio.

3. TownePlace Suites by Marriott Jacksonville East

TownePlace Suites by Marriott Jacksonville East
3.0 star property
3 km from Isle of Palms
9.2 out of 10, Wonderful, (659 reviews)
"Great location close to the beach. Super well maintained facility. Everything was great!"
United States
gregory
The price is ₹11,402
₹12,941 total
includes taxes & fees
4 Oct - 5 Oct
TownePlace Suites by Marriott Jacksonville East
A hotel lobby with a bar area, seating arrangements, and a reception desk.

4. Hampton Inn & Suites Jacksonville - Beach Blvd/Mayo Clinic

Hampton Inn & Suites Jacksonville - Beach Blvd/Mayo Clinic
2.5 star property
3 km from Isle of Palms
9.0 out of 10, Wonderful, (1,003 reviews)
"Great place to stay."
United States
Patsy
The price is ₹10,490
₹11,906 total
includes taxes & fees
4 Oct - 5 Oct
Hampton Inn & Suites Jacksonville - Beach Blvd/Mayo Clinic
An outdoor patio with seating, a fire pit, and string lights.

5. Hyatt Place Jacksonville / St. Johns Town Center

Hyatt Place Jacksonville / St. Johns Town Center
3.0 star property
9.7 km from Isle of Palms
9.2 out of 10, Wonderful, (1,167 reviews)
"Great staff, great breakfast, and very clean."
United States
Marty
The price is ₹12,188
₹13,833 total
includes taxes & fees
1 Oct - 2 Oct
Hyatt Place Jacksonville / St. Johns Town Center
A modern restaurant with a bar area, wooden ceiling, and large windows.

6. Hilton Jacksonville at Mayo Clinic near Beaches

Hilton Jacksonville at Mayo Clinic near Beaches
4.5 star property
2.1 km from Isle of Palms
9.4 out of 10, Exceptional, (359 reviews)
"Excellent hotel and staff."
United States
Kristen
The price is ₹16,971
₹19,262 total
includes taxes & fees
17 Oct - 18 Oct
Hilton Jacksonville at Mayo Clinic near Beaches
A spacious lobby with a glass floor, a reception desk, and a view of the ocean.

7. Margaritaville Jacksonville Beach

Margaritaville Jacksonville Beach
2.5 star property
Oceanfront, 4.6 km from Isle of Palms
9.0 out of 10, Wonderful, (4,511 reviews)
"Great location with beautiful views, clean, beautiful rooms and lots to do around the area"
United States
Keisha
The price is ₹14,267
₹16,195 total
includes taxes & fees
21 Oct - 22 Oct
Margaritaville Jacksonville Beach
A hotel room with a large bed, a desk with a chair, a television, and a mirror.

8. Holiday Inn Jacksonville E 295 Baymeadows by IHG

Holiday Inn Jacksonville E 295 Baymeadows by IHG
3.0 star property
9.8 km from Isle of Palms
8.6 out of 10, Excellent, (1,000 reviews)
"Great Hotel"
United States
Josh
The price is ₹7,934
₹9,005 total
includes taxes & fees
22 Oct - 23 Oct
Holiday Inn Jacksonville E 295 Baymeadows by IHG
An outdoor patio area with wicker furniture, a fire feature, and string lights.

9. Sheraton Jacksonville Hotel

Sheraton Jacksonville Hotel
4.0 star property
10.7 km from Isle of Palms
9.2 out of 10, Wonderful, (1,005 reviews)
"Good location, clean"
United States
Kerrie
The price is ₹11,850
₹13,449 total
includes taxes & fees
25 Sept - 26 Sept
Sheraton Jacksonville Hotel
A laptop on a wooden desk with a white mug, a spoon, and a smartphone.

10. Hyatt Studios Jacksonville/St Johns Town Center

Hyatt Studios Jacksonville/St Johns Town Center
2.5 star property
8.9 km from Isle of Palms
9.4 out of 10, Exceptional, (212 reviews)
"Very nice stay, they have grab and go breakfast as complimentary."
United States
Phi
The price is ₹10,707
₹12,152 total
includes taxes & fees
1 Oct - 2 Oct
Hyatt Studios Jacksonville/St Johns Town Center
A self-service beverage station with a refrigerated display and a coffee machine.

11. Tru By Hilton Jacksonville St Johns Town Center

Tru By Hilton Jacksonville St Johns Town Center
2.5 star property
9.7 km from Isle of Palms
9.2 out of 10, Wonderful, (960 reviews)
"Very convenient location and easy check in and out. Rooms were clean and quiet. Breakfast was great!"
United States
Mary
The price is ₹10,466
₹11,878 total
includes taxes & fees
4 Oct - 5 Oct
Tru By Hilton Jacksonville St Johns Town Center
A hotel room with two beds, a desk with a computer, a chair, and a colorful carpet.

12. Holiday Inn Express Jacksonville Beach by IHG

Holiday Inn Express Jacksonville Beach by IHG
3.0 star property
3.3 km from Isle of Palms
9.2 out of 10, Wonderful, (1,004 reviews)
"The staff was nice, and the breakfast was very good,"
United States
Jose
The price is ₹11,306
₹12,833 total
includes taxes & fees
28 Sept - 29 Sept
Holiday Inn Express Jacksonville Beach by IHG
A beach with a sandy shore, waves, and buildings in the background.

13. Best Western Oceanfront

Best Western Oceanfront
3.0 star property
Oceanfront, 4.4 km from Isle of Palms
9.0 out of 10, Wonderful, (1,001 reviews)
"This is one of the best kept Best Western hotels I’ve ever been in. The hotel is walkable to the beach, dining, and activities. Parking is easy. The staff are very friendly and breakfast was varied for everyone’s needs."
United States
Sonya
The price is ₹12,086
₹13,718 total
includes taxes & fees
24 Sept - 25 Sept
Best Western Oceanfront
A covered entrance with a dark tiled floor, white columns, and a green bench.

14. Hampton Inn Jacksonville/Ponte Vedra Beach-Mayo Clinic Area

Hampton Inn Jacksonville/Ponte Vedra Beach-Mayo Clinic Area
2.5 star property
3.7 km from Isle of Palms
9.0 out of 10, Wonderful, (1,232 reviews)
"Room was clean, staff were very pleasant and helpful. Will definitely stay here again when I come back to Jacksonville."
United States
Robert
The price is ₹11,321
₹12,849 total
includes taxes & fees
4 Oct - 5 Oct
Hampton Inn Jacksonville/Ponte Vedra Beach-Mayo Clinic Area
A spacious lobby with a reception desk, seating area, and large windows.

15. Hilton Garden Inn Jacksonville Ponte Vedra Sawgrass

Hilton Garden Inn Jacksonville Ponte Vedra Sawgrass
3.0 star property
8.7 km from Isle of Palms
9.2 out of 10, Wonderful, (1,002 reviews)
"Great in every way!! Very comfortable and clean and friendly"
United States
Joyce
The price is ₹11,262
₹12,557 total
includes taxes & fees
19 Oct - 20 Oct
Hilton Garden Inn Jacksonville Ponte Vedra Sawgrass
A hotel with a central building and two wings, featuring a well-lit entrance and a clear sky.

16. Homewood Suites by Hilton Jacksonville-South/St. Johns Ctr.

Homewood Suites by Hilton Jacksonville-South/St. Johns Ctr.
3.0 star property
9.1 km from Isle of Palms
8.6 out of 10, Excellent, (1,000 reviews)
"Staff was ,polite and attentive, my four year old felt at home and loved breakfast. The friendliest stay we have had in a while. Highly recommended them."
United States
Maria
The price is ₹10,899
₹12,370 total
includes taxes & fees
4 Oct - 5 Oct
Homewood Suites by Hilton Jacksonville-South/St. Johns Ctr.
A spacious hotel atrium with multiple floors, a central staircase, and lush indoor plants.

17. Embassy Suites by Hilton Jacksonville Baymeadows

Embassy Suites by Hilton Jacksonville Baymeadows
3.5 star property
14.2 km from Isle of Palms
8.4 out of 10, Very good, (1,504 reviews)
"Clean & will stay again"
United States
Timothy
The price is ₹11,314
₹12,841 total
includes taxes & fees
27 Sept - 28 Sept
Embassy Suites by Hilton Jacksonville Baymeadows
A modern outdoor seating area with white wicker chairs, a glass fire pit with burning wood, and a view of palm trees and a building in the background.

18. Element by Marriott Jacksonville Beach

Element by Marriott Jacksonville Beach
3.0 star property
Oceanfront, 4.2 km from Isle of Palms
9.6 out of 10, Exceptional, (587 reviews)
"Nice lodging a block from the beach. Great food nearby."
United States
Nick
The price is ₹14,564
₹16,530 total
includes taxes & fees
1 Oct - 2 Oct
Element by Marriott Jacksonville Beach
A hotel courtyard with outdoor seating, potted plants, and a modern building facade.

19. Aloft by Marriott Jacksonville Tapestry Park

Aloft by Marriott Jacksonville Tapestry Park
3.0 star property
12 km from Isle of Palms
9.0 out of 10, Wonderful, (1,001 reviews)
"Everything we wanted. Great stay!"
United States
Lee
The price is ₹12,849
₹14,584 total
includes taxes & fees
27 Sept - 28 Sept
Aloft by Marriott Jacksonville Tapestry Park

20. Four Points by Sheraton Jacksonville Beachfront

Four Points by Sheraton Jacksonville Beachfront
3.0 star property
Oceanfront, 4.3 km from Isle of Palms
9.0 out of 10, Wonderful, (1,006 reviews)
"Awesome stay"
United States
Susan
The price is ₹17,022
₹19,320 total
includes taxes & fees
4 Oct - 5 Oct
Four Points by Sheraton Jacksonville Beachfront
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Where to stay in Isle of Palms

Find the best Isle of Palms areas for the activities you enjoy most.
A city skyline with modern skyscrapers, a prominent Wells Fargo building, and a blue bridge over a river.
Photo by Ryan Ketterman
Open Photo by Ryan Ketterman

Downtown Jacksonville

The picturesque St. Johns River meanders through the center of this hub of skyscrapers, cultural landmarks and exciting nightlife.

A coastal cityscape at dusk with a prominent clock tower, waterfront, and historic buildings.

Amelia City

While visiting Amelia City, you might make a stop by sights like American Beach and Fernandina Beach.

A sunset over a beach with waves and a pier.

Oceanfront

While visiting Oceanfront, you might make a stop by sights like Oceanfront Park and Northeast Florida Beaches.

A city skyline at night with illuminated buildings and a bridge reflecting on the water.

Southside

If you're spending some time in Southside, St. Johns Town Center and Orange Park Place Shopping Center are top sights worth seeing.

A golf course with a pond, trees, and buildings in the background.

Sawgrass

Beaches and riverfront are just a few things travellers like about Sawgrass. A stop by Mickler Beach is also recommended if you've got time to explore the area.

Top Isle of Palms Hotel Reviews

Springhill Suites By Marriott Jacksonville Beach Oceanfront

Springhill Suites By Marriott Jacksonville Beach Oceanfront

10/10 Excellent
"This was my fist visit and it will not be my last. Everyone was very helpful ( Anthony) with the in service on closing the balcony door. Javier and Haley with the friendly and helpful assistance with the meal at the SandBar."
Marie 2-night trip
Posted 2 hours ago
Springhill Suites By Marriott Jacksonville Beach Oceanfront

Frequently asked questions

What is Isle of Palms like?
Travellers are sure to enjoy a stay in Jacksonville Beach's Isle of Palms neighbourhood.
What's a favourite hotel to stay in Isle of Palms?
Based on our traveller data, Residence Inn By Marriott Jacksonville - Mayo Clinic Area is one of the top choices for your stay in Isle of Palms. This hotel is a short 6-minute walk from Mayo Clinic Florida, and it offers free breakfast and an outdoor pool.
How many hotels should I expect to find in Isle of Palms?
Expedia has 39 hotels and other accommodation options in Isle of Palms to choose from, making this an ideal home base for exploring the greater Jacksonville Beach area.
If I need to cancel my hotel reservation in Isle of Palms, will I receive a refund?
Yes! You'll find that most hotel room reservations are fully refundable as long as you cancel before the accommodation's cancellation deadline, which is often 24 or 48 hours before your check-in date. If you booked a non-refundable reservation, you may still be able to cancel and get a refund within a 24-hour period of booking. Enter your dates, click on "Search", then you can use the "fully refundable" filter to view the best deals available in Isle of Palms.
What is there to do in this Jacksonville Beach neighbourhood?
A few places to visit in the area around Isle of Palms include Cradle Creek Preserve, Jacksonville Beach Golf Club and Windsor Parke Golf Club. While you're out sightseeing in Jacksonville Beach, make sure that you visit other sights such as Players by the Sea or Rhoda Martin Cultural Heritage Center.