Isle of Palms Trip

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Where to stay in Isle of Palms

Find the best Isle of Palms areas and neighborhoods for the activities you enjoy most. Learn more about Isle of Palms
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Southside

1 out of top 10 points of interest in this area

If you're spending some time in Southside, St. Johns Town Center and Orange Park Place Shopping Center are top sights worth seeing.

Find hotels in Southside

Top hotels in Isle of Palms

Residence Inn By Marriott Jacksonville - Mayo Clinic Area

Residence Inn By Marriott Jacksonville - Mayo Clinic Area

3 out of 5
4905 SAN PABLO ROAD SOUTH, Jacksonville, FL
Fully refundableReserve now, pay when you stay
The price is ₹13,881 per night from 7 Nov to 8 Nov
₹13,881
₹15,755 total
7 Nov - 8 Nov
includes taxes & fees
9.4/10 Exceptional! (432 reviews)
Always comfortable, beautiful rooms, great beds, great service, spotless clean

Reviewed on 21 Oct 2025

Residence Inn By Marriott Jacksonville - Mayo Clinic Area
Hyatt Regency Jacksonville

Hyatt Regency Jacksonville

4 out of 5
225 E Coastline Dr, Jacksonville, FL
Fully refundableReserve now, pay when you stay
The price is ₹12,651 per night from 23 Nov to 24 Nov
₹12,651
₹14,502 total
23 Nov - 24 Nov
includes taxes & fees
8.8/10 Excellent! (1,336 reviews)
Still haven't received the deposit back but the hotel is plush A+

Reviewed on 24 Oct 2025

Hyatt Regency Jacksonville
Margaritaville Jacksonville Beach

Margaritaville Jacksonville Beach

2.5 out of 5
715 1st St N, Jacksonville Beach, FL
Fully refundableReserve now, pay when you stay
8.8/10 Excellent! (3,284 reviews)
It was a great stay, it was raining for much of the weekend it was a great room

Reviewed on 25 Oct 2025

Get rates
Margaritaville Jacksonville Beach
See all 3,148 properties in Isle of Palms
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does an Isle of Palms holiday package cost?
Starting from as low as , you can build your own Isle of Palms holiday package. Simply bundle flights, hotels and car rentals and be rewarded with discounts.
How do I get a cheap travel package to Isle of Palms?
If you love getting a great deal, bundle your bookings into an Isle of Palms holiday package. Whether you need hotels, flights, day tours or rental cars, you can book them all in one place. You'll have ample choice at your fingertips too. Expedia has over 550 air carriers and 1,000,000 hotels all over the world to take your pick of. Fly with who you prefer, stay wherever you like and save precious money — now that's the ideal escape!
Where should I stay in Isle of Palms?
Make sightseeing a breeze by staying someplace right around the corner from Isle of Palms's big attractions. St. Johns Town Centre and University of North Florida are two traveller favourites.
What are the top hotels in Isle of Palms?
Get your trip off to a great start by locking in a room at The Retreat Close To Mayo Clinic. It's one of most sought-after hotels in Isle of Palms. Another top option is Residence Inn By Marriott Jacksonville - Mayo Clinic Area.
How far in advance should I book my Isle of Palms holiday?
Your best bet is to book early. Airlines usually advertise flights nearly 12 months prior to departure, and this is a perfect opportunity to land some of the lowest prices. Boss just told you to take your holiday time next week? No sweat. Expedia are never short on fantastic deals to whisk you away on the getaway of your dreams, at a price you can afford.
What does an Expedia Isle of Palms travel package include?
From hotels and flights to car rentals, Expedia can help you shape an Isle of Palms package that's perfect for you. Holidaying for a while? Look into a rental car, flight and hotel bundle. If you can only squeeze in a quick getaway, a hotel and airfare deal could suit you better. Experiences can also be added once you've made your booking. Our holiday packages make it a breeze to save and plan.
What should I know before booking an Isle of Palms travel package?
A travel package can be easier on the hip pocket than individually booking everything you need for your adventure. For example, bundle your hotels, flights and rental cars and save a pretty penny. Whatever sort of holiday you're planning, there's sure to be a package that matches your budget.
Can I choose my airline with an Isle of Palms Expedia holiday package?
Yes, the choice is all yours. We have access to over 550 partner airlines throughout the world, so you can design your Isle of Palms trip according to your travel needs.
If I'm not able to travel, can I cancel my Isle of Palms holiday package?
Because we understand life is full of surprises, the answer is yes. To find out more, check out our Customer Service Portal. But generally speaking, if you've booked your package in the last 24 hours, you may be able to cancel or change it with no penalties. Your airline, hotel or car rental company may charge a fee if your booking is older than that.

Popular places to visit

Jacksonville Naval Air Station

Jacksonville Naval Air Station

After visiting Jacksonville Naval Air Station, make a plan to see the other sights and activities in Jacksonville. Experience the lively festivals or attend a sporting event in this family-friendly area.

Jacksonville Naval Air Station
EverBank Field which includes a lake or waterhole

EverBank Stadium

Capable of seating over 80,000 fans, this modern football stadium is the exciting home of the Jacksonville Jaguars, international soccer games and music events.

EverBank Stadium
Jacksonville Zoo and Gardens

Jacksonville Zoo and Gardens

Admire thousands of animals and plants across entertaining exhibits in this family-friendly zoo that also has a children’s play area and a 4-D experience.

Jacksonville Zoo and Gardens
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.