A beach with palm trees, people relaxing on chairs, and colorful kayaks.

Search Luxury Hotels in Florida Keys

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in
  • Be picky

    Search almost a million properties worldwide

Check availability on Florida Keys Luxury Hotels

Tonight
22 Sept - 23 Sept
Tomorrow
23 Sept - 24 Sept
This weekend
25 Sept - 27 Sept
Next weekend
2 Oct - 4 Oct

Our top choices for Florida Keys luxury hotels

1. The Islands of Islamorada

The Islands of Islamorada
Matecumbe
₹39,668
₹50,702 total
includes taxes & fees
1 Oct - 2 Oct
The Islands of Islamorada

2. Villas At Hawks Cay Resort

Villas At Hawks Cay Resort
Marathon
  • Indulge in oceanfront splendour at this Florida Keys resort with 5 pools, private beach, and full-service spa treatments.
₹36,337
₹46,812 total
includes taxes & fees
23 Sept - 24 Sept
Villas At Hawks Cay Resort

3. Santa Maria Suites

Santa Maria Suites
Old Town Key West
  • Lavish Key West retreat features luxury suites, designer touches, 2 pools, and vibrant bar scene.
₹26,733
₹36,542 total
includes taxes & fees
23 Sept - 24 Sept
Santa Maria Suites

4. Opal Key Resort & Marina, Key West

Opal Key Resort & Marina, Key West
Old Town Key West
₹24,816
₹31,692 total
includes taxes & fees
23 Sept - 24 Sept
Opal Key Resort & Marina, Key West

5. Playa Largo Resort & Spa, Autograph Collection

Playa Largo Resort & Spa, Autograph Collection
Rock Harbor
  • Beachfront luxury awaits at this Key Largo resort with spa treatments and ocean views.
₹25,200
₹33,632 total
includes taxes & fees
6 Oct - 7 Oct
Playa Largo Resort & Spa, Autograph Collection

6. Hyatt Centric Key West Resort and Spa

Hyatt Centric Key West Resort and Spa
Key West Historic District
₹21,380
₹30,740 total
includes taxes & fees
28 Sept - 29 Sept
Hyatt Centric Key West Resort and Spa

7. Ocean Key Resort - A Noble House Resort

Ocean Key Resort - A Noble House Resort
Key West Historic District
₹23,537
₹33,918 total
includes taxes & fees
11 Oct - 12 Oct
Ocean Key Resort - A Noble House Resort

8. Pier House Resort & Spa

Pier House Resort & Spa
Key West Historic District
₹21,184
₹30,515 total
includes taxes & fees
28 Sept - 29 Sept
Pier House Resort & Spa

9. Reefhouse Resort & Marina

Reefhouse Resort & Marina
Key Largo
₹19,079
₹25,300 total
includes taxes & fees
30 Sept - 1 Oct
Reefhouse Resort & Marina

10. Baker's Cay Resort Key Largo, Curio Collection by Hilton

Baker's Cay Resort Key Largo, Curio Collection by Hilton
Key Largo
  • Beach luxury reimagined at Key Largo resort with private sands, refreshing pools, and coastal dining.
₹22,721
₹30,847 total
includes taxes & fees
1 Oct - 2 Oct
Baker's Cay Resort Key Largo, Curio Collection by Hilton
View all properties

Find out more about Florida Keys

Florida Keysand its attractions for luxury travelers

The Florida Keys offer an exquisite playground for luxury travellers seeking both relaxation and adventure. Begin your journey in Key West, where you can explore the vibrant streets lined with historical architecture and indulge in exquisite dining at renowned establishments like Latitudes, known for its stunning sunset views and fresh seafood. Next, venture to the tranquil surroundings of Little Palm Island, a private resort accessible only by boat or seaplane, where you can unwind in a thatched-roof bungalow with unparalleled ocean views and a full-service spa. For those interested in marine life, a day trip to the Dry Tortugas National Park is a must; here, you can snorkel in crystal-clear waters, discovering vibrant coral reefs and diverse wildlife. The Keys also boast some of the finest fishing opportunities, with charter services available to take you out for a day on the water, targeting species like tarpon and bonefish. Finally, enjoy the laid-back elegance of Islamorada, where luxury resorts such as Cheeca Lodge offer lavish accommodations alongside activities like paddleboarding and sunset cruises. Staying in these luxurious settings ensures that every detail of your experience is catered to, allowing you to focus on making unforgettable memories.

Top Florida Keys Hotel Reviews

Chesapeake Beach Resort

Chesapeake Beach Resort

8/10 Good
"Very quiet and peaceful stay. Amazing water and beach views from the balcony."
Michelle 4-night trip
Posted 4 hours ago
Chesapeake Beach Resort
Lime Tree Bay Resort

Lime Tree Bay Resort

10/10 Excellent
"I absolutely loved my stay at Lime Tree Bay Resort! The property is beautiful, relaxing, and has that perfect laid-back Florida Keys atmosphere. The views are gorgeous, and it was such a peaceful place to unwind and enjoy the water and sunshine. Everything was clean and comfortable, and the staff was friendly and welcoming. I especially loved being able to relax by the pool and just enjoy the beautiful surroundings. The location is also great for exploring Islamorada and the rest of the Keys. I would definitely stay here again and highly recommend Lime Tree Bay Resort to anyone looking for a relaxing Keys getaway. I was honestly sad to leave!"
STACIE 1-night trip
Posted 5 hours ago
Lime Tree Bay Resort
Hampton Inn Key Largo Manatee Bay

Hampton Inn Key Largo Manatee Bay

10/10 Excellent
"Nice place"
Travis 1-night trip
Posted 8 hours ago
Hampton Inn Key Largo Manatee Bay
Baker's Cay Resort Key Largo, Curio Collection by Hilton

Baker's Cay Resort Key Largo, Curio Collection by Hilton

10/10 Excellent
"What is unique about the property is how convenient and practical is the property, excellent for families! Always a nice experience"
Sonia 3-night trip
Posted 10 hours ago
Baker's Cay Resort Key Largo, Curio Collection by Hilton
The Pelican Key Largo Cottages

The Pelican Key Largo Cottages

10/10 Excellent
"The Pelican is a darling spot! Lots of space, convenient parking right next to our door, beautiful sandy beach area, well maintained dock, plenty of comfy Adirondack chairs in multiple spots to watch the water - the boats, fish, birds, and manatees. We really enjoyed the use of kayaks as well. Just a lovely property and stay."
Heidi 1-night trip
Posted 11 hours ago
The Pelican Key Largo Cottages
Bayside Inn Key Largo

Bayside Inn Key Largo

10/10 Excellent
"We stayed here for 2 nights and chose this hotel for the proximity to the dive shop we were diving with on their boat. It was a good choice with clean rooms and nice staff. Bonus SNOOKS restaurant & Tiki Bar right on the water! We would stay here again!"
Jamie 2-night trip
Posted 12 hours ago
Bayside Inn Key Largo
Islander Resort

Islander Resort

10/10 Excellent
"Nice pool"
Henry 1-night trip
Posted 13 hours ago
Islander Resort
Reefhouse Resort & Marina

Reefhouse Resort & Marina

10/10 Excellent
"Opal takes pride ownership in running a customer service excellence resort The champagne touch is nice Thank you Dr Fajardo Garcia"
Onelia 1-night trip
Posted 14 hours ago
Reefhouse Resort & Marina
Hawks Cay Resort

Hawks Cay Resort

8/10 Good
"The village we were assigned has roaches and the main bedroom has the pain from the felling peeling which could be a hazard. Also, the water park that was supposed to be completed on September has a delay and that was the main reason a reserve this hotel."
Miladis 2-night trip
Posted 17 hours ago
Hawks Cay Resort

Explore a world of travel with Expedia