Commerce Hotels from ₹5,641

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18 Dec - 19 Dec
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19 Dec - 20 Dec
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19 Dec - 21 Dec
Next weekend
26 Dec - 28 Dec

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Our top choices for Commerce hotels

Exterior
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
2.5 star property
Cape Girardeau
9.4 out of 10, Exceptional, (1000)
This centrally located hotel offers convenient access to restaurants and shopping. Take advantage of the indoor pool and fitness centre after exploring nearby Cape Splash Family Aquatic Centre. Free breakfast, WiFi, and parking enhance your stay with attentive staff ready to assist.
"We like to stay at this hotel on our way to New Orleans and on our return trip to Wisconsin. It is convenient, clean, breakfast options are excellent and the 8 pm cookie time is always a hit. Staff are also very friendly. "
United States
Brian
The price is ₹8,586
₹9,686 total
includes taxes & fees
24 Dec - 25 Dec
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
Lobby
Courtyard by Marriott Cape Girardeau Downtown

Courtyard by Marriott Cape Girardeau Downtown

Courtyard by Marriott Cape Girardeau Downtown
3.0 star property
Cape Girardeau
9.6 out of 10, Exceptional, (468)
Wake up to Mississippi River views at this city centre hotel, steps from Riverfront Park and Shawnee National Forest. After exploring, return to The Bistro for American cuisine or unwind at the bar. The 24-hour fitness centre and in-room refrigerators enhance your stay.
"The staff was very helpful and friendly. The rooms were modern and clean. The downtown location was perfect for us. "
United States
Deborah
The price is ₹10,483
₹11,879 total
includes taxes & fees
28 Dec - 29 Dec
Courtyard by Marriott Cape Girardeau Downtown
Property amenity
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
3.0 star property
Jackson
8.8 out of 10, Excellent, (669)
"Great place "
United States
GUY
The price is ₹7,605
₹8,230 total
includes taxes & fees
19 Dec - 20 Dec
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
Lobby
Pear Tree Inn Cape Girardeau Near the Medical Center

Pear Tree Inn Cape Girardeau Near the Medical Center

Pear Tree Inn Cape Girardeau Near the Medical Center
2.5 star property
Cape Girardeau
9.0 out of 10, Wonderful, (1002)
This peaceful hotel offers a quiet atmosphere just minutes from Shawnee National Forest and Cape Splash Family Aquatic Centre. Nearby restaurants and stores enhance convenience while helpful staff ensure a comfortable stay with free WiFi and daily housekeeping.
"Nice place for a stay at a reasonable price."
United States
Arthur
The price is ₹6,325
₹7,136 total
includes taxes & fees
23 Dec - 24 Dec
Pear Tree Inn Cape Girardeau Near the Medical Center
Desk, laptop workspace, blackout curtains, iron/ironing board
Quality Inn Charleston - Sikeston

Quality Inn Charleston - Sikeston

Quality Inn Charleston - Sikeston
2.5 star property
Charleston
6.8 out of 10, (406)
Located in a serene area of Charleston, this Quality Inn offers free daily buffet breakfast between 6-9 AM. Enjoy complimentary WiFi and parking, with Cape Girardeau Municipal Airport just 37 minutes away. Guests consistently praise the well-maintained facilities.
"The staff was very friendly and accommodating "
United States
Arturo
The price is ₹5,938
₹6,589 total
includes taxes & fees
28 Dec - 29 Dec
Quality Inn Charleston - Sikeston
Courtyard
Hampton Inn Cape Girardeau I 55 East

Hampton Inn Cape Girardeau I 55 East

Hampton Inn Cape Girardeau I 55 East
2.5 star property
Cape Girardeau
9.6 out of 10, Exceptional, (784)
Located near Shawnee National Forest and Mississippi River, this hotel offers complimentary breakfast, WiFi and parking. Unwind in the indoor pool, utilise the fitness centre or relax on the terrace. Clean rooms feature refrigerators and microwaves.
"Excellent stay"
United States
Christina
The price is ₹9,189
₹10,367 total
includes taxes & fees
25 Dec - 26 Dec
Hampton Inn Cape Girardeau I 55 East
Lobby
Comfort Suites Jackson-Cape Girardeau

Comfort Suites Jackson-Cape Girardeau

Comfort Suites Jackson-Cape Girardeau
2.5 star property
Jackson
8.2 out of 10, Very good, (739)
Modern comfort awaits at this Jackson hotel with an indoor pool and fitness centre. Explore nearby Shawnee National Forest or visit Cape Girardeau Conservation Nature Centre after enjoying the complimentary breakfast and WiFi.
"Dirty "
United States
Jon
The price is ₹7,212
₹7,805 total
includes taxes & fees
28 Dec - 29 Dec
Comfort Suites Jackson-Cape Girardeau
Business centre
Drury Inn & Suites Cape Girardeau

Drury Inn & Suites Cape Girardeau

Drury Inn & Suites Cape Girardeau
3.0 star property
Cape Girardeau
9.4 out of 10, Exceptional, (1003)
Walking distance to restaurants and shops, this peaceful hotel offers complimentary breakfast, WiFi, and parking. Swim year-round in the indoor pool or unwind in the hot tub after exploring nearby attractions like Cape Splash Family Aquatic Centre.
"Very friendly staff and great breakfast"
United States
Ray
The price is ₹8,133
₹9,174 total
includes taxes & fees
23 Dec - 24 Dec
Drury Inn & Suites Cape Girardeau
Lobby
Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center
3.0 star property
Cape Girardeau
9.6 out of 10, Exceptional, (1001)
Explore Shawnee National Forest from this Cape Girardeau hotel offering complimentary breakfast, WiFi, and parking. Enjoy the indoor pool and hot tub after a day out, or dine at The Southerner restaurant. Each room includes handy refrigerators and microwaves.
"Great place and staff, very accommodating!"
United States
Megan
The price is ₹8,133
₹9,174 total
includes taxes & fees
23 Dec - 24 Dec
Drury Plaza Hotel Cape Girardeau Conference Center
Desk, iron/ironing board, free WiFi, alarm clocks
Eagle Inn Charleston

Eagle Inn Charleston

Eagle Inn Charleston
2.0 star property
Charleston
6.8 out of 10, (103)
Discover relaxation at this Charleston motel offering complimentary WiFi and parking. The on-site health club provides fitness options after exploring local attractions. Cape Girardeau Municipal Airport is just a 43-minute drive away.
"Middle of nowhere hotel was ok"
United States
David
The price is ₹5,467
₹6,067 total
includes taxes & fees
19 Dec - 20 Dec
Eagle Inn Charleston
Lobby sitting area
The Riverview

The Riverview

The Riverview
4.0 star property
Cape Girardeau
9.4 out of 10, Exceptional, (474)
Located near Riverfront Park and Isle Casino, this business-friendly hotel offers exciting gaming, 2 restaurants including Beacon 53 for American cuisine, plus free WiFi and parking for convenient exploration of Cape Girardeau.
"The room was clean and the mattress was extremely comfortable "
United States
Stacy
The price is ₹8,008
₹9,034 total
includes taxes & fees
22 Dec - 23 Dec
The Riverview
Property amenity
Drury Inn & Suites Sikeston, MO

Drury Inn & Suites Sikeston, MO

Drury Inn & Suites Sikeston, MO
3.0 star property
Sikeston
9.4 out of 10, Exceptional, (1000)
Located just off the highway near Sikeston dining and shopping, this hotel offers both indoor and outdoor pools for year-round swimming. Guests praise the peaceful atmosphere, helpful staff, and complimentary breakfast, parking, and WiFi.
"Clean room, great location and friendly staff"
United States
Mark
The price is ₹8,133
₹9,350 total
includes taxes & fees
23 Dec - 24 Dec
Drury Inn & Suites Sikeston, MO
Front of property – evening/night
Super 8 by Wyndham Charleston/Sikeston East MO

Super 8 by Wyndham Charleston/Sikeston East MO

Super 8 by Wyndham Charleston/Sikeston East MO
2.0 star property
Charleston
6.6 out of 10, (612)
This Charleston motel offers complimentary on-the-go breakfast and WiFi for a hassle-free stay. Guests appreciate the helpful staff and free parking. Located within driving distance of Cape Girardeau Municipal Airport for easy regional access.
"Staff was great! Room was nice. "
United States
Lana
The price is ₹5,612
₹6,228 total
includes taxes & fees
19 Dec - 20 Dec
Super 8 by Wyndham Charleston/Sikeston East MO
Lobby
Pear Tree Inn Cape Girardeau West

Pear Tree Inn Cape Girardeau West

Pear Tree Inn Cape Girardeau West
2.5 star property
Cape Girardeau
9.0 out of 10, Wonderful, (1000)
Wake up to complimentary breakfast at this quiet retreat near Shawnee National Forest. Guests love the peaceful atmosphere, helpful staff, and convenient location close to Cape Splash Family Aquatic Centre. Free WiFi and parking enhance the overall value.
"Great stay"
United States
Heather
The price is ₹6,325
₹7,136 total
includes taxes & fees
23 Dec - 24 Dec
Pear Tree Inn Cape Girardeau West
Room, 2 Queen Beds
Tru By Hilton Cape Girardeau

Tru By Hilton Cape Girardeau

Tru By Hilton Cape Girardeau
2.5 star property
Cape Girardeau
9.6 out of 10, Exceptional, (102)
Conveniently located near Shawnee National Forest, this Cape Girardeau hotel offers morning swims in the indoor pool and energising workouts at the fitness centre. Enjoy free breakfast before exploring nearby nature attractions.
"It was a nice stay"
United States
Douglas
The price is ₹8,078
₹9,193 total
includes taxes & fees
24 Dec - 25 Dec
Tru By Hilton Cape Girardeau
Lobby
Quality Inn Cairo I-57

Quality Inn Cairo I-57

Quality Inn Cairo I-57
2.5 star property
Cairo
6.6 out of 10, (273)
Start your day with complimentary full breakfast before exploring nearby attractions. This hotel provides free WiFi and parking, making it an ideal base for visiting Fort Defiance State Park and Ballard Wildlife Management Area.
"Break fast was excellent "
United States
Uma
The price is ₹6,609
₹7,335 total
includes taxes & fees
17 Jan - 18 Jan 2026
Quality Inn Cairo I-57
Exterior
Candlewood Suites Cape Girardeau by IHG

Candlewood Suites Cape Girardeau by IHG

Candlewood Suites Cape Girardeau by IHG
2.5 star property
Cape Girardeau
8.2 out of 10, Very good, (882)
"Room was clean and spacious."
United States
George
The price is ₹7,140
₹8,551 total
includes taxes & fees
21 Dec - 22 Dec
Candlewood Suites Cape Girardeau by IHG
Lobby
Fairfield Inn & Suites by Marriott Cape Girardeau

Fairfield Inn & Suites by Marriott Cape Girardeau

Fairfield Inn & Suites by Marriott Cape Girardeau
2.5 star property
Cape Girardeau
9.4 out of 10, Exceptional, (139)
Enjoy free continental breakfast and complimentary parking at this modern Cape Girardeau retreat. The indoor pool offers year-round swimming, while Fort D Historic Site and Cape Splash Family Aquatic Centre are just minutes away.
"Nice hotel, clean and comfortable "
United States
Laura
The price is ₹7,953
₹8,972 total
includes taxes & fees
28 Dec - 29 Dec
Fairfield Inn & Suites by Marriott Cape Girardeau
Iron/ironing board, free WiFi, bed sheets
Country Yard Inn and Suite

Country Yard Inn and Suite

Country Yard Inn and Suite
2.0 star property
Sikeston
6.8 out of 10, (120)
This Sikeston motel offers a convenient base for exploring nearby Central Park and Sikeston Depot Museum. Enjoy thoughtful amenities like free WiFi and parking alongside 24-hour front desk service for assistance anytime.
"Great spot en route home from Mississippi. Staff put me in a room that ended up being in a quiet section of the hotel. Great sleep."
United States
Andrew
The price is ₹4,830
₹5,746 total
includes taxes & fees
19 Dec - 20 Dec
Country Yard Inn and Suite
Standard Room, 1 Queen Bed, Non Smoking, Garden View | Free WiFi
Rockwood Inn

Rockwood Inn

Rockwood Inn
2.0 star property
Cape Girardeau
10.0 out of 10, Exceptional, (18)
Located just minutes from popular attractions like Show Me Centre and Isle Casino, this hotel offers free WiFi and parking. Relax in the garden after exploring Cape Girardeau's highlights, with convenient access to the municipal airport.
"We came into town for a concert and had a blast! The hotel was super comfy, and the staff were friendly. The rooms were very clean and the decor was beautiful! "
United States
Vanessa
The price is ₹12,495
₹14,097 total
includes taxes & fees
30 Dec - 31 Dec
Rockwood Inn
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Commerce Hotel Reviews

Quality Inn

Quality Inn

10/10 Excellent
"Comfortable bed"
Grace 1-night trip
Posted 2 days ago
Quality Inn

More cheap stays in Commerce

Baymont by Wyndham Columbia, MO

Baymont by Wyndham Columbia, MO

2500 I 70 Dr Sw Columbia MO
The price is ₹4,993 per night from 25 Dec to 26 Dec
₹4,993
₹5,641 total
25 Dec - 26 Dec
includes taxes & fees
8/10 Very Good! (619 reviews)

Frequently asked questions

What's the best place to stay in Commerce?
Drury Plaza Hotel Cape Girardeau Conference Center, located 12.6 mi (20.3 km) from the heart of Commerce, is a top choice for your stay, based on our traveller data. Two other choices for your visit to the area are The Riverview and La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau. See all available top hotels, or vacation rentals in Commerce.
If I need to cancel my hotel reservation in Commerce, will I receive a refund?
Yes! The majority of hotel bookings are refundable provided that you cancel prior to the accommodation's cancellation deadline, which often is within 24-48 hours of your arrival date. If your reservation is non-refundable, you might be able to cancel it and be given a refund within a 24-hour period of booking. Filter your search by fully refundable to find flexible hotel deals in Commerce.
How is it to stay in Commerce?
Travellers to Commerce will find plenty to explore and enjoy. There are 80 hotels and other accommodation options in the surrounding area. Find out more about Commerce.
What should I see while I'm in Commerce?
A favourite place to visit is Mississippi River. You'll also find Isle Casino Cape Girardeau and Show Me Center in the area. Take a look at what more there is to see and do in Expedia's Commerce guide.
What's the seasonal weather in Commerce?
The hottest months are usually July and August, with an average temperature of 25°C, while the coldest months are January and February, with an average of 5°C. Average annual precipitation for Commerce is 1491 mm.