TOP Luxury Hotels in Central Missouri, MO for 2026

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Our top choices for Central Missouri luxury hotels

4 restaurants; breakfast, lunch, dinner and brunch served

1. voco The Tiger Hotel Columbia, MO by IHG

Columbia

Historic charm meets modern luxury in Columbia's heart with pillowtop beds, 24-hour service, and immaculate spaces.

₹14,124

₹17,543 total

includes taxes & fees

6 Sept - 7 Sept

Breakfast, lunch, dinner and brunch served

Two double beds non smoking | Premium bedding, down duvets, in-room safe, desk

2. DoubleTree by Hilton Hotel Jefferson City

Jefferson City

₹11,660

₹13,392 total

includes taxes & fees

3 Sept - 4 Sept

2 restaurants; breakfast, lunch and dinner served

3. Camden on the Lake Resort & Spa

Lake Ozark

Lakeside spa resort offers luxury treatments and poolside cocktails for a serene escape.

₹10,280

₹14,730 total

includes taxes & fees

7 Sept - 8 Sept

4. Lodge Of Four Seasons Golf Resort, Marina & Spa

Lake Ozark

Lakeside retreat features spa treatments, 36 holes of championship golf, and Japanese gardens.

₹9,620

₹12,697 total

includes taxes & fees

1 Sept - 2 Sept

Desk, laptop workspace, blackout curtains, iron/ironing board

5. Drury Plaza Hotel Columbia East

Columbia

₹8,970

₹10,134 total

includes taxes & fees

23 Aug - 24 Aug

6. The Broadway Columbia - a DoubleTree by Hilton

Columbia

₹12,443

₹14,119 total

includes taxes & fees

28 Aug - 29 Aug

7. Boat Slip & Water Views: Lake Ozark Condo

Lake Ozark

8. Pet-friendly Downtown Fulton Apt w/ Smart TV!

Fulton

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Top Central Missouri Hotel Reviews

Best Western Plus Columbia Inn

10/10 Excellent

"No complaints."

Stoney Creek Hotel Columbia

10/10 Excellent

"great spot that is close to everything at Mizzou!"

Margaritaville Lake Resort Lake of the Ozarks

10/10 Excellent

"Room was clean and big people were very helpful and wasn't overly priced"

Lodge Of Four Seasons Golf Resort, Marina & Spa

8/10 Good

"The website needs updated or they need to put information books in the room. I could not find information on the amenities anywhere as far as hours and price or something that spells out what specifically is included in our stay. Nothing is complimentary except pool access and towels. The grounds were pretty, nice pools, the resort is in a located.. would e joyed our stay more if there was some kind of complimentary breakfast or coffee bar and if access to spa amenities like the sauna and steam room were included. Staff was excellent."

Days Inn by Wyndham Rolla

8/10 Good

"I was traveling by myself with my yorkies, (which is hard enough) but they were accommodating and kind and very welcoming of my fur babies. Not all hotels are like that. Even if they claim to be “pet friendly” they’re not always “friendly” about it. But I was pleasantly welcomed. I’d stay again!"

Days Inn by Wyndham Osage Beach Lake of the Ozarks

10/10 Excellent

"This was a very accommodating hotel. It was clean and even served a decent breakfast."

Ramada by Wyndham Columbia

8/10 Good

"Staff was very helpful"

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Our top choices for Central Missouri luxury hotels

1. voco The Tiger Hotel Columbia, MO by IHG