Compare and book 5 Star hotels in South Carolina Lowcountry, South Carolina
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Top South Carolina Lowcountry 5 Star Hotels

Montage Palmetto Bluff
Montage Palmetto Bluff

Anchorage 1770
Anchorage 1770

Montage Palmetto Bluff Residences
Montage Palmetto Bluff Residences
Explore similar 4-star hotels

Sonesta Resort Hilton Head Island
Learn more about South Carolina Lowcountry
Discover things to see and do in South Carolina Lowcountry as you venture to popular sights like Marine Corps Recruit Depot Parris Island.

Find out more about South Carolina Lowcountry
Find out more about South Carolina Lowcountry
Stay in Luxury: 5 Star Hotels in South Carolina Lowcountry
There's nothing wrong with enjoying the finer things in life. Indulge your every desire on your upcoming leisure time. Treat yourself with a stay in a 5-star hotel during your South Carolina Lowcountry trip. You'll join the multitudes of holidaymakers who have made South Carolina Lowcountry so fashionable recently. You can also expect excellent customer service from these hotels, so get ready to kick back and indulge. Don't wait any longer. Reserve one of our 5-star hotels in South Carolina Lowcountry and indulge in the finer things in life for a while.
5-Star Hotels in South Carolina Lowcountry
You'll have a wonderful time at one of these 5-star hotels. Exceptional customer care, luxurious bedding, and deeply relaxing spa offerings are waiting for you. You're sure to find exactly the accommodation you need. You can also expect excellent customer service from these hotels, so get ready for a wonderful adventure. What kind of amenities will make your stay a wonderful one? 24-hour room service, so you can order that berry tart in the wee hours of the morning? A body scrub that will leave you feeling refreshed and alive? Butler services? Whatever it is your heart desires, you're bound to find it here. Don't want to take our word for it? Explore our listings and pick the perfect accommodation for your needs.
But you aren't going to spend your entire holiday in your room, of course. You're in luck. From doing a bit of shopping to embracing the great outdoors, you'll never be bored on this retreat. No matter what's on your agenda, the 5-star hotels in South Carolina Lowcountry are waiting for you to relax after an exciting day.
Make Your Escape
The results are in, and South Carolina Lowcountry 5-star hotels are the place to be when you book your next holiday. If you've been dreaming about a holiday set here, then go ahead and book it. It's time to plan your next great escape -- this is a great time to find 5-star hotel deals in South Carolina Lowcountry! Choose one of our South Carolina Lowcountry 5-star hotels today and soothe yourself in luxe surroundings at your convenience.
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Top South Carolina Lowcountry Hotel Reviews

Montage Palmetto Bluff
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Explore a world of travel with Expedia
Hotels in South Carolina Lowcountry by Star Rating
Areas of South Carolina Lowcountry
Accommodation near South Carolina Lowcountry attractions
- Hotels near Marine Corps Recruit Depot Parris Island
- Hotels near Sea Pines Forest Preserve
- Hotels near Edisto Beach State Park
- Hotels near Harbour Town Lighthouse
- Hotels near Palmetto Dunes Tennis & Pickleball Center
- Hotels near May River Golf Club at Palmetto Bluff
- Hotels near Shipyard Golf Course
- Hotels near South Carolina Welcome Center
More accommodation types in South Carolina Lowcountry
- Apartments in South Carolina Lowcountry
- Condo Rentals in South Carolina Lowcountry
- Motels in South Carolina Lowcountry
- Holiday Homes in South Carolina Lowcountry
- Cottages in South Carolina Lowcountry
- Aparthotels in South Carolina Lowcountry
- Condo Resorts in South Carolina Lowcountry
- Resorts in South Carolina Lowcountry
- Villas in South Carolina Lowcountry
- B&B in South Carolina Lowcountry
- Guest Houses in South Carolina Lowcountry
- Inns in South Carolina Lowcountry
Explore more hotels
- Hotel Carolina, a Days Inn by Wyndham
- Red Roof Inn Hilton Head Island
- Home2 Suites by Hilton Hilton Head
- Montage Palmetto Bluff
- Red Roof Inn Hardeeville
- Spark By Hilton Hilton Head Island
- Spark by Hilton Bluffton Hilton Head Island
- Hampton Inn Hilton Head
- Courtyard by Marriott Hilton Head Island
- Island Links Resort by Palmera
- Holiday Inn Hotel & Suites Beaufort at Highway 21 by IHG
- SpringHill Suites by Marriott Beaufort
- Tru by Hilton Beaufort, SC
- Okatie Hilton Head Hotel
- Simple Rewards Inn
- Best Western Plus Bluffton / Hilton Head Hotel
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