Compare and book 5 Star hotels in Panama City, Panamá Province
Change your mindBook hotels with free cancellation
Be pickySearch almost a million properties worldwide
Check availability on Panama City 5 Star Hotels
Our top choices for Panama City 5-star hotels
4. Renaissance Panama City Hotel
Renaissance Panama City Hotel
6. The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
Explore similar 4-star hotels
Crowne Plaza Panama Airport by IHG
Central Hotel Panama Casco Viejo
Waymore Hotel Spa & Casino
Learn more about Panama City
The gleaming skyscrapers of this cosmopolitan capital stand in striking contrast to the colonial charm of Casco Viejo. Watch massive ships navigate the Canal locks, then sample ceviche at the seafood market where local fishermen bring their daily catch.
See all hotels in Panama City
Top Panama City Hotel Reviews
Renaissance Panama City Hotel
"I was very satisfied"
Waldorf Astoria Panama
"Dede el ingress estuvimos super bien recibidos hasta el check in y en lahabitacion super bien el de say unto muy recommendable y gran atencion"
Find out more about Panama City
Stay in Luxury: 5 Star Hotels in Panama City
There's nothing wrong with enjoying the finer things in life. Indulge your every desire on your upcoming leisure time. Treat yourself with a stay in a 5-star hotel during your Panama City trip. You'll join the multitudes of holidaymakers who have made Panama City so fashionable recently. You can also expect excellent customer service from these hotels, so get ready to kick back and indulge. Don't wait any longer. Reserve one of our 5-star hotels in Panama City and indulge in the finer things in life for a while.
5-Star Hotels in Panama City
You'll have a wonderful time at one of these 5-star hotels. Exceptional customer care, luxurious bedding, and deeply relaxing spa offerings are waiting for you. You're sure to find exactly the accommodation you need. You can also expect excellent customer service from these hotels, so get ready for a wonderful adventure. What kind of amenities will make your stay a wonderful one? 24-hour room service, so you can order that berry tart in the wee hours of the morning? A body scrub that will leave you feeling refreshed and alive? Butler services? Whatever it is your heart desires, you're bound to find it here. Don't want to take our word for it? Explore our listings and pick the perfect accommodation for your needs.
But you aren't going to spend your entire holiday in your room, of course. You're in luck. From doing a bit of shopping to embracing the great outdoors, you'll never be bored on this retreat. No matter what's on your agenda, the 5-star hotels in Panama City are waiting for you to relax after an exciting day.
Make Your Escape
The results are in, and Panama City 5-star hotels are the place to be when you book your next holiday. If you've been dreaming about a holiday set here, then go ahead and book it. It's time to plan your next great escape -- this is a great time to find 5-star hotel deals in Panama City! Choose one of our Panama City 5-star hotels today and soothe yourself in luxe surroundings at your convenience.
Expedia India is rated 4 stars by Feefo based on 1038 reviews
Frequently asked questions
What are the best 5-star hotels in Panama City?
How much does it cost to stay in a 5-star hotel in Panama City?
- Search for the lowest price per night from ₹10,782
What makes a hotel 5 stars in Panama City?
Explore a world of travel with Expedia
- Hotels near Albrook Shopping Mall
- Hotels near Amador Convention Center
- Amador Hotels
- Hotels near Avenida Balboa
- Balboa Hotels
- Bella Vista Hotels
- Bethania Hotels
- Historic Hotels in Casco Viejo
- Hotels Suites in Casco Viejo
- Casco Viejo Hotels
- Adults Only Resorts & in Costa del Este
- Costa del Este Hotels
- All-Inclusive Hotels in Panamá Province
- Cheap Hotels in Panamá Province
- Golf Hotels in Panamá Province
- Scuba Diving Hotels in El Cangrejo
- El Cangrejo Hotels
- Hotels near Isla Flamenco Shopping Center
- Adults Only Resorts & in Marbella
- Beach Resorts & in Marbella
- Boutique Hotels in Marbella
- Family-Friendly Hotels in Marbella
- Scuba Diving Hotels in Marbella
- Hotels near Miraflores Locks
- Hotels near Multicentro Panama
- Hotels near Multiplaza Pacific Mall
- Hotels near Panama Canal Railway
- Aparthotels in Panama City
- Cruise Ships in Panama City
- Holiday Parks in Panama City
- Adults Only Resorts & in Panama City
- All-Inclusive Hotels in Panama City
- Beach Resorts & in Panama City
- Boutique Hotels in Panama City
- Cheap Hotels in Panama City
- Family-Friendly Hotels in Panama City
- Hotels Suites in Panama City
- Hotels with Views in Panama City
- Hotels with Airport Transfers in Panama City
- Hotels with Early Check-in in Panama City
- Luxury Hotels in Panama City
- Romantic Hotels in Panama City
- Ski Hotels in Panama City
- Panama City Hotels
- Lodges in Panama City
- Palaces in Panama City
- Castles in Panama City Passenger Station
- Hotels near Panama City Passenger Station
- B&B in Panamá Province
- Country Houses in Panamá Province
- Cruise Ships in Panamá Province
- Hotels near Panama Viejo
- Rio Abajo Hotels
- San Antonio Hotels
- Hotels with Parking in San Francisco
- Hotels with Balcony in San Francisco
- Scuba Diving Hotels in San Francisco
- Santa Ana Hotels
- Hotels near Soho City Center
- Hotels near Vía Argentina