Sikeston, Missouri, is a delightful destination that offers a range of attractions for all types of travelers. The downtown area is filled with charming cafes, family-friendly dining options, and unique shopping experiences. The city center is conveniently located close to various hotels, making it an ideal base for exploring Sikeston and its surrounding areas. Visitors can enjoy the friendly atmosphere and warm hospitality of the local people while embarking on exciting excursions to the nearby river, university, and museums. Sikeston truly captures the essence of a quintessential American town with its rich history and vibrant culture.

Sikeston Hotels from ₹6,087
- Change your mindBook hotels with free cancellation
- Be pickySearch almost a million properties worldwide
Go beyond your typical stay in Sikeston
Family friendly
Check prices for these dates
Our top choices for Sikeston hotels

Drury Inn & Suites Sikeston, MO
Drury Inn & Suites Sikeston, MOSikeston
9.6 out of 10, Exceptional, (1,019 reviews)
The price is ₹10,652
₹12,247 total
includes taxes & fees
6 Jul - 7 Jul

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHGCape Girardeau
9.4 out of 10, Exceptional, (1,004 reviews)
The price is ₹10,462
₹11,803 total
includes taxes & fees
28 Jun - 29 Jun

Drury Plaza Hotel Cape Girardeau Conference Center
Drury Plaza Hotel Cape Girardeau Conference CenterCape Girardeau
9.6 out of 10, Exceptional, (1,014 reviews)
The price is ₹9,510
₹10,729 total
includes taxes & fees
28 Jun - 29 Jun

Hampton Inn Sikeston
Hampton Inn SikestonSikeston
9.0 out of 10, Wonderful, (578 reviews)
The price is ₹10,841
₹12,275 total
includes taxes & fees
1 Jul - 2 Jul

Drury Inn & Suites Cape Girardeau
Drury Inn & Suites Cape GirardeauCape Girardeau
9.4 out of 10, Exceptional, (1,014 reviews)
The price is ₹8,559
₹9,656 total
includes taxes & fees
28 Jun - 29 Jun

Fairfield Inn & Suites by Marriott Sikeston
Fairfield Inn & Suites by Marriott SikestonSikeston
9.4 out of 10, Exceptional, (89 reviews)
The price is ₹11,604
₹13,138 total
includes taxes & fees
22 Jun - 23 Jun

Pear Tree Inn Cape Girardeau West
Pear Tree Inn Cape Girardeau WestCape Girardeau
9.0 out of 10, Wonderful, (1,014 reviews)
The price is ₹6,847
₹7,725 total
includes taxes & fees
28 Jun - 29 Jun

The Riverview
The RiverviewCape Girardeau
9.4 out of 10, Exceptional, (598 reviews)
The price is ₹11,577
₹13,060 total
includes taxes & fees
16 Jun - 17 Jun

Courtyard by Marriott Cape Girardeau Downtown
Courtyard by Marriott Cape Girardeau DowntownCape Girardeau
9.6 out of 10, Exceptional, (518 reviews)
The price is ₹11,899
₹13,483 total
includes taxes & fees
28 Jun - 29 Jun

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
La Quinta Inn & Suites by Wyndham Jackson/Cape GirardeauJackson
9.0 out of 10, Wonderful, (785 reviews)
The price is ₹8,812
₹9,537 total
includes taxes & fees
16 Jun - 17 Jun

Drury Inn & Suites Jackson MO
Drury Inn & Suites Jackson MOJackson
9.6 out of 10, Exceptional, (1,019 reviews)
The price is ₹7,703
₹8,144 total
includes taxes & fees
28 Jun - 29 Jun

Holiday Inn Express & Suites Sikeston Southwest by IHG
Holiday Inn Express & Suites Sikeston Southwest by IHGSikeston
8.6 out of 10, Excellent, (468 reviews)
The price is ₹10,177
₹11,523 total
includes taxes & fees
28 Jun - 29 Jun

Tru By Hilton Cape Girardeau
Tru By Hilton Cape GirardeauCape Girardeau
9.6 out of 10, Exceptional, (135 reviews)
The price is ₹8,686
₹9,886 total
includes taxes & fees
6 Jul - 7 Jul

Hampton Inn Cape Girardeau I 55 East
Hampton Inn Cape Girardeau I 55 EastCape Girardeau
9.6 out of 10, Exceptional, (822 reviews)
The price is ₹10,061
₹11,350 total
includes taxes & fees
28 Jun - 29 Jun

Best Western Plus Sikeston I-55
Best Western Plus Sikeston I-55Sikeston
8.4 out of 10, Very good, (1,012 reviews)
The price is ₹8,293
₹9,452 total
includes taxes & fees
14 Jul - 15 Jul

Fairfield Inn & Suites by Marriott Cape Girardeau
Fairfield Inn & Suites by Marriott Cape GirardeauCape Girardeau
9.4 out of 10, Exceptional, (199 reviews)
The price is ₹8,812
₹9,941 total
includes taxes & fees
28 Jun - 29 Jun

TownePlace Suites by Marriott Sikeston
TownePlace Suites by Marriott SikestonSikeston
9.2 out of 10, Wonderful, (18 reviews)
The price is ₹12,079
₹13,677 total
includes taxes & fees
16 Jul - 17 Jul

Rockwood Inn
Rockwood InnCape Girardeau
10.0 out of 10, Exceptional, (20 reviews)
The price is ₹13,533
₹15,268 total
includes taxes & fees
23 Jun - 24 Jun

Super 8 by Wyndham Sikeston/Miner Area
Super 8 by Wyndham Sikeston/Miner AreaSikeston
7.0 out of 10, Good, (646 reviews)
The price is ₹6,249
₹7,124 total
includes taxes & fees
14 Jul - 15 Jul

Quality Inn Cape Girardeau North
Quality Inn Cape Girardeau NorthCape Girardeau
7.2 out of 10, Good, (757 reviews)
The price is ₹6,420
₹7,243 total
includes taxes & fees
28 Jun - 29 Jun
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in
Stay near popular Sikeston attractions
Sikeston and related destinations
Home to Lambert's Café, the 'Home of Throwed Rolls,' where servers toss fresh bread across the room to hungry diners. Visit the historic Sikeston Depot or catch the annual rodeo where professional cowboys compete in thrilling events each August.

Top Sikeston Hotel Reviews

Pear Tree Inn Cape Girardeau West
10/10 Excellent
More cheap stays in Sikeston

Super 8 by Wyndham Sikeston/Miner Area
2609 E Malone Ave Sikeston MO
The price is ₹6,249 per night from 14 Jul to 15 Jul
₹6,249
₹7,124 total
14 Jul - 15 Jul
includes taxes & fees
7/10 Good! (646 reviews)
Hotels in Sikeston with star rating

3 Star Hotels
20 properties
Find out more about Sikeston
Hidden gem of Southern charm in Sikeston, Missouri
Find your hotel in Sikeston
Experience the top activities and must-see sights in Sikeston
How to find great deals and cheap hotels in Sikeston
Discover the flavours of Sikeston
Best time to go to Sikeston
The Sikeston info point: What you need to know
Category | Details |
|---|---|
| Location | Sikeston, Missouri, United States |
| Population | Approximately 16,000 |
| Climate | Humid subtropical |
| Best time to visit | Spring and fall |
| Must-see attractions | Mississippi River, Lambert's Cafe, Sikeston Depot Museum |
| Local cuisine | Barbecue, Southern comfort food |
| Popular events | Sikeston Jaycee Bootheel Rodeo, Sikeston Cotton Carnival |
| Nearby cities | Cape Girardeau, Poplar Bluff, Paducah (Kentucky) |
Frequently asked questions
Explore a world of travel with Expedia
- Advance Hotels
- B&B in Benton
- Motels in Bragg City
- Campbell Hotels
- Resorts in Cape Girardeau
- All-Inclusive Hotels in Cape Girardeau
- Cheap Hotels in Cape Girardeau
- Hotels with Breakfast in Cape Girardeau
- Motels in Cape Girardeau
- B&B in Charleston
- Cape Girardeau County Hotels
- Resorts in Greenville
- Hotels Suites in Hayti
- Cheap Hotels in Jackson
- Hotels Suites in Jackson
- Hotels near Southeast Missouri State University












































































