Florida Keys Spa Holidays 2026

Plan, book, travel with confidence
Better together
Save up to ₹100,000 when you book a flight and hotel together*
Find the right fit
With over 300,000 hotels worldwide, it's easy to create a perfect package
Rest easy
Plan, book, and manage your trip all in one place

Top Spa Florida Keys Hotels

Cheeca Lodge & Spa

81801 Overseas Highway, Mile Marker 82 Islamorada FL

3 hours drive from Florida Keys Beaches

Stay at this luxury resort in Islamorada. Enjoy free parking, 3 outdoor pools and a full-service spa. Our guests praise the pool and the helpful staff in their ...

Pier House Resort & Spa

1 Duval St Key West FL

37 min drive from Florida Keys Beaches

Stay at this beach resort in Key West. Enjoy a full-service spa, a private beach and 2 bars/lounges. Our guests praise the pool and the helpful staff in their ...

Southernmost Beach Resort and Guesthouses

1319 Duval Street Key West FL

36 min drive from Florida Keys Beaches

Stay at this beach hotel in Key West. Enjoy free Wi-Fi, 3 outdoor pools and a full-service spa. Our guests praise the pool and the helpful staff in their reviews. ...

8.8/10 Excellent! (3,490 reviews)

Travellers like: full-service spa, massage, facials, couples spa treatments

Travellers say...

"The place is very old and outdated. Small rooms and lots of things that are out of service and don’t work. One positive is the breakfast package is totally worth the money. Food is amazing. Overall we made the best of our stay despite the inconveniences."

Reviewed on 8 Aug 2026

See all 8,267 properties in Florida Keys

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.