Top Romantic Southern Minnesota Hotels

Alexander Mansion Bed and Breakfast

274 East Broadway, Winona, MN

2 hours drive from Mayo Clinic

Stay at this 3.5-star B&B in Winona. Enjoy free breakfast, free parking and a business centre. Popular attractions Watkins Heritage Museum and Polish Cultural ...

10/10 Exceptional! (341 reviews)

"Check in was great with the owner telling us about the history of the house. Breakfast was excellent!"

Reviewed on 14 Jul 2025

St James Hotel, a Historic Hotel of America

406 Main St., Red Wing, MN

2 hours drive from Mayo Clinic

Stay at this 3.5-star spa hotel in Red Wing. Enjoy free Wi-Fi, free parking and a full-service spa. Our guests praise the helpful staff and the comfy rooms in ...

9/10 Wonderful! (1,000 reviews)

Couples like: full-service spa, bar

Lovely historical hotel!

"This hotel is absolutely stunning and a must-stay when in Red Wing. So much to explore within the building itself. Wonderful on-site restaurant with a patio and weekend music. Within walking distance of everything you need. The complimentary YMCA pass is a plus."

Reviewed on 6 Jul 2025

AmericInn by Wyndham Austin

1700 8th St NW, Austin, MN

2 hours drive from Mayo Clinic

Stay at this business-friendly hotel in Austin. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the helpful staff and the clean rooms in ...

8.8/10 Excellent! (672 reviews)

"I'd stay here again on my yearly road trip. Affordable and clean"

Reviewed on 19 Jul 2025

See all 1,166 properties in Southern Minnesota

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.