Photo by Southernmost Illinois Tourism Bureau

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Top Pet-friendly Southwest Illinois Hotels

La Quinta Inn & Suites by Wyndham O'Fallon, IL - St. Louis

136 Regency Park O'Fallon IL

4 hours drive from Lake of Egypt

Stay at this business-friendly hotel in O'Fallon. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the clean rooms in their reviews. Popular ...

5.8/10 (1,001 reviews)

The room was comfotable and clean slept well but the coffe maker didnt work and the shampoo dispenser was empty

Reviewed on 11 May 2026

Red Roof Inn St Louis - Troy, IL

2030 Formosa Road Troy IL

4 hours drive from Lake of Egypt

Stay at this business-friendly hotel in Troy. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the helpful staff and the clean rooms in their ...

7.8/10 Good! (1,001 reviews)

Microwave was extremely dirty everything in the room had dust shower curtain was dirty fridge had tape holding the shelves up in it toilet took forever to flush bathroom amenities where used and some didn't have lids on them like the shower soap but the dust was the main thing it looked like the ...

Reviewed on 30 Apr 2026

La Quinta Inn & Suites by Wyndham Collinsville - St. Louis

6 Gateway Dr Collinsville IL

4 hours drive from Lake of Egypt

Stay at this business-friendly hotel in Collinsville. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the helpful staff and the clean rooms ...

7.4/10 Good! (1,004 reviews)

The place was clean and well maintained. However, we were surprised by the additional pet fee. That should have been indicated before we made the reservation.

Reviewed on 11 May 2026

See all 760 properties in Southwest Illinois

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.