
South Carolina Midlands Pet-friendly Holidays
Book a Pet-friendly Hotel + Flight or Car together to unlock savings
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Top Pet-friendly South Carolina Midlands Hotels

La Quinta Inn & Suites by Wyndham Florence
2123 W Lucas St Florence SC
Stay at this business-friendly hotel in Florence. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the breakfast and the helpful staff in ...

La Quinta Inn by Wyndham Columbia SE / Fort Jackson
7333 Garners Ferry Rd Columbia SC
Stay at this business-friendly hotel in Columbia. Enjoy free breakfast, free Wi-Fi and free parking. Popular attractions Williams Brice Stadium and Colonial ...
8.4/10 Very good! (1,040 reviews)
"The front desk was extremely helpful when I called in because there was a blob of black hair and a tiny black something on the bottom sheet of one of the beds. The young lady came in and stripped the whole bed and put clean sheets and blankets on the previously soiled bed. In the morning, the shower ..."
Reviewed on 11 Nov 2026

Hampton Inn Columbia I-26/Harbison Blvd.
101 Woodcross Dr Columbia SC
Stay at this business-friendly hotel in Columbia. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the breakfast and the helpful staff in ...
9.2/10 Wonderful! (1,005 reviews)
"Room was clean and so was the bathroom , great service as well !"
Reviewed on 9 Nov 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.
