Photo by Southernmost Illinois Tourism Bureau

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Top Kid friendly Southwest Illinois Hotels

Country Inn & Suites by Radisson, Marion, IL

1306 Halfway Road Marion IL

43 min drive from Southern Illinois University

Stay at this business-friendly hotel in Marion. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the breakfast and the helpful staff in their ...

8.6/10 Excellent! (1,002 reviews)

"Clean and convenient for our overnight stay. Well-maintained facility."

Reviewed on 20 Jun 2026

Drury Plaza Hotel Mt. Vernon

145 North 44th Street Mount Vernon IL

2 hours drive from Southern Illinois University

Stay at this business-friendly hotel in Mount Vernon. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the breakfast and the helpful staff ...

9.6/10 Exceptional! (1,711 reviews)

"Clean room, great staff, drinks and dinner excellent….great stay!!"

Reviewed on 21 Jun 2026

Comfort Inn & Suites O'Fallon - St. Louis Area

116 Regency Park O'Fallon IL

3 hours drive from Southern Illinois University

Stay at this business-friendly hotel in O'Fallon. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the helpful staff in their reviews. Popular ...

6.4/10 (157 reviews)

"All the sheets, towels, and linens were stained. We had to request another room to get sheets that were less stained but still stained. The front desk could care less about service and acted like we were a bother. The breakfast nook is dirty and not maintained. I would not stay here again."

Reviewed on 18 Jun 2026

See all 758 properties in Southwest Illinois

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.