Photo by Southernmost Illinois Tourism Bureau

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Top Kid friendly Southwest Illinois Hotels

Country Inn & Suites by Radisson, Marion, IL

1306 Halfway Road Marion IL

43 min drive from Southern Illinois University

Stay at this business-friendly hotel in Marion. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the breakfast and the helpful staff in their ...

8.6/10 Excellent! (1,002 reviews)

Let me start with the staff here is amazing! However it is right off the main road so you can hear the road noise at night. The breakfast was ok nothing amazing. The room was very clean big and the bed was super comfortable. We had some problems with the TV but the front desk lady helped us out with ...

Reviewed on 22 Mar 2026

Drury Plaza Hotel Mt. Vernon

145 North 44th Street Mount Vernon IL

2 hours drive from Southern Illinois University

Stay at this business-friendly hotel in Mount Vernon. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the breakfast and the helpful staff ...

9.6/10 Exceptional! (1,659 reviews)

Everything was great!

Reviewed on 23 Mar 2026

Comfort Inn & Suites O'Fallon - St. Louis Area

116 Regency Park O'Fallon IL

3 hours drive from Southern Illinois University

Stay at this business-friendly hotel in O'Fallon. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the helpful staff in their reviews. Popular ...

6.8/10 (120 reviews)

NO WE WANTED A SUITE WITH QUEEN BEDS TAKING A FRIEND FOR SURGERY IN ST LOUIS !! ADVERTISEMENT ON THE ROOM SAID A SUITE THIS PLACE HAS NO SUCH ROOM!! THE FRINT DESK( ( WE KNOW THEIR NAME) SAID THAT IT HAPPENS ALOT !! I STAY AT COMFORT SUITE INNS ALWAYS !! THIS ONE WAS DISSAPPOINTING WILL NOT STAY ...

Reviewed on 16 Mar 2026

See all 746 properties in Southwest Illinois

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.