Photo by Southernmost Illinois Tourism Bureau

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Top Kid friendly Southwest Illinois Hotels

Country Inn & Suites by Radisson, Marion, IL

1306 Halfway Road Marion IL

43 min drive from Southern Illinois University

Stay at this business-friendly hotel in Marion. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the breakfast and the helpful staff in their ...

8.4/10 Very Good! (1,001 reviews)

friendly staff and room was good

Reviewed on 28 Jan 2026

Drury Plaza Hotel Mt. Vernon

145 North 44th Street Mount Vernon IL

2 hours drive from Southern Illinois University

Stay at this business-friendly hotel in Mount Vernon. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the breakfast and the helpful staff ...

9.6/10 Exceptional! (1,653 reviews)

Yvette and the Entire staff made Our stay Perfect.... including Upgrade room.

Reviewed on 3 Feb 2026

Comfort Inn & Suites O'Fallon - St. Louis Area

116 Regency Park O'Fallon IL

3 hours drive from Southern Illinois University

Stay at this business-friendly hotel in O'Fallon. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the helpful staff in their reviews. Popular ...

6.8/10 (100 reviews)

Room was clean. One bed had a “divot” — asked for a solution, but nothing was done.

Reviewed on 11 Jan 2026

See all 740 properties in Southwest Illinois

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.