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Top Beach Southeast Jacksonville Hotels

Hampton Inn & Suites Jacksonville - Beach Blvd/Mayo Clinic

13733 Beach Blvd Jacksonville FL

4 min drive from Mayo Clinic Florida

Stay at this business-friendly hotel in Jacksonville. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the breakfast and the helpful staff ...

8.8/10 Excellent! (1,000 reviews)

Very clean. Staff friendly and courteous.

Reviewed on 13 Jan 2026

Wyndham Garden Jacksonville

4660 Salisbury Road Jacksonville FL

10 min drive from Mayo Clinic Florida

Stay at this business-friendly hotel in Jacksonville. Enjoy free Wi-Fi, free parking and a fitness centre. Our guests praise the helpful staff and the clean ...

7.8/10 Good! (1,785 reviews)

Travellers like: near the beach, beach bars, outdoor pool

Travellers say...

Facility is clean but dated. Rooms could use an upgrade. Bed was very comfortable.

Reviewed on 13 Jan 2026

Delta Hotels by Marriott™ Jacksonville Deerwood

4700 Salisbury Rd Jacksonville FL

10 min drive from Mayo Clinic Florida

Stay at this business-friendly hotel in Jacksonville. Enjoy free parking, breakfast (surcharge) and a free local area shuttle. Our guests praise the helpful ...

8.4/10 Very Good! (507 reviews)

Very clean

Reviewed on 13 Jan 2026

See all 540 properties in Southeast Jacksonville

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.