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Top Adventure Southern Minnesota Hotels

Kahler Grand Hotel

20 2nd Ave Sw Rochester MN

2 min walk from Mayo Clinic

Stay at this business-friendly hotel in Rochester. Enjoy free Wi-Fi, 2 restaurants and breakfast (surcharge). Our guests praise the helpful staff and the clean ...

8.2/10 Very Good! (1,828 reviews)

Room was clean, rooftop, pool, and sauna was a great spot to relax. The convenience of walking around underground in the winter to get to stores and restaurants is genius! Check out at noon too! Only issue was we have a large truck

Reviewed on 11 Dec 2025

Country Inn & Suites by Radisson, Rochester, MN

4323 Highway 52 North, West Frontage Rd Rochester MN

10 min drive from Mayo Clinic

Stay at this business-friendly hotel in Rochester. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the helpful staff in their reviews. Popular ...

7.4/10 Good! (1,002 reviews)

Yes, but the bread for toast was dried out stale.

Reviewed on 8 Dec 2025

AmericInn by Wyndham Mankato Event Center

240 Stadium Road Mankato MN

4 hours drive from Mayo Clinic

Stay at this business-friendly hotel in Mankato. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the breakfast and the helpful staff in ...

9/10 Wonderful! (1,004 reviews)

Was was very nice and clean.

Reviewed on 13 Dec 2025

See all 1,196 properties in Southern Minnesota

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.