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Top Adventure Southern Minnesota Hotels

Kahler Grand Hotel

20 2nd Ave Sw Rochester MN

2 min walk from Mayo Clinic

Stay at this business-friendly hotel in Rochester. Enjoy free Wi-Fi, 2 restaurants and breakfast (surcharge). Our guests praise the helpful staff and the clean ...

8.4/10 Very good! (2,164 reviews)

"I loved it was right across the street from Mayo Clinic. On Thursday evenings downtown they have a marvelous festival with music and so many vendors. You have to check out the fudge. The staff was great and I received immediate results from questions and requests."

Reviewed on 26 Jun 2026

Willow Inn Suites Rochester

4323 Highway 52 North, West Frontage Rd Rochester MN

10 min drive from Mayo Clinic

Stay at this business-friendly hotel in Rochester. Enjoy free Wi-Fi, free parking and a 24-hour front desk. Our guests praise the helpful staff in their reviews. ...

AmericInn by Wyndham Mankato Event Center

240 Stadium Road Mankato MN

4 hours drive from Mayo Clinic

Stay at this business-friendly hotel in Mankato. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the breakfast and the helpful staff in ...

9.2/10 Wonderful! (1,004 reviews)

"Breakfast had many of options. They also offered free snacks and beverages both early evenings. The fitness machines could use some mantanance."

Reviewed on 26 Jun 2026

See all 1,189 properties in Southern Minnesota

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.