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Top flight + Adults Only hotel deals in Gulf Coast

Price found within the past 48 hours. Click for updated prices.

Southernmost House

Old Town Key West

Save 100% on your flight

₹258,818

per person

15 Mar - 20 Mar

found 1 day ago

Return direct flight included

Rochester (ROC) to Key West (EYW)

9.4/10 Exceptional! (1,001 reviews)

Excellent location, friendly staff, great amenities. Very happy we stayed there!

Reviewed on 28 Jan 2026

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Top Adults Only Gulf Coast Hotels

Shoreline Island Resort - Exclusively Adult

14200 Gulf Boulevard Madeira Beach FL

59 min drive from Port of Tampa

Stay at this beach aparthotel in Madeira Beach. Enjoy free Wi-Fi, free parking and a beach locale. Our guests praise the helpful staff in their reviews. Popular ...

9.2/10 Wonderful! (1,444 reviews)

Room was spotless bedding was exceptional The staff is wonderful this is our 3rd time at the shoreline

Reviewed on 8 Jan 2026

The Southernmost Inn - Adults Only

525 United Street Key West FL

9 hours drive from Port of Tampa

Stay at this hotel in Key West. Enjoy free breakfast, 2 outdoor pools and parking (surcharge). Our guests praise the breakfast and the pool in their reviews. ...

8.2/10 Very Good! (1,261 reviews)

Room was clean, staff helpful and amenities were great.

Reviewed on 25 Jan 2026

Upper Deck Hotel and Bar - Adults Only

120 E Atol St. South Padre Island TX

Stay at this hotel in South Padre Island. Enjoy free Wi-Fi, free parking and 2 bars/lounges. Our guests praise the helpful staff in their reviews. Popular attractions ...

9.2/10 Wonderful! (171 reviews)

Great entertainment!

Reviewed on 28 Dec 2025

See all 183,142 properties in Gulf Coast

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.