Florida Keys Adults Only Holidays 2026

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Top Adults Only Florida Keys Hotels

The Southernmost Inn - Adults Only

525 United Street Key West FL

9 min walk from Duval Street

Stay at this hotel in Key West. Enjoy free breakfast, 2 outdoor pools and parking (surcharge). Our guests praise the breakfast and the pool in their reviews. ...

8.4/10 Very good! (1,427 reviews)

"I traveled solo and stayed in the Attic Room. The room I stayed in is bigger than it looks in the pictures. There is a small private bathroom with shower stall. The room doesn't get super cold but the AC keeps it comfortable. (I think a table fan would be a great addition to the room) There is a ..."

Reviewed on 18 Aug 2026

Paradise Inn Key West - Adults Only

819 Simonton Street Key West FL

4 min walk from Duval Street

Stay at this business-friendly hotel in Key West. Enjoy free breakfast, parking (surcharge) and a garden. Our guests praise the breakfast and the pool in their ...

Heron House - Adult Only

512 Simonton St Key West FL

3 min walk from Duval Street

Stay at this B&B in Key West. Enjoy free breakfast, free Wi-Fi and a rooftop terrace. Our guests praise the breakfast and the pool in their reviews. Popular ...

See all 8,304 properties in Florida Keys

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.