Lodging Image

Search Hotels in Uptown Greenville, Greenville

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

This weekend
16 Oct - 18 Oct
Next weekend
23 Oct - 25 Oct

Filter by

Star rating

Guest rating

Selecting then applying a filter from this group will update the results on a new page

Our top choices for Uptown Greenville hotels

A modern hotel with a stone facade, large windows, and a well-lit entrance.

1. Hilton Garden INN Greenville University

Hilton Garden INN Greenville University
3.0 star property
Uptown Greenville
9.4 out of 10, Exceptional, (175 reviews)
"Really nice and new hotel."
United States
Sharon
The price is ₹12,800
₹14,464 total
includes taxes & fees
25 Oct - 26 Oct
Hilton Garden INN Greenville University
A modern hotel room with a large bed, a desk with a chair, a flat-screen TV mounted on the wall, and a wardrobe.

2. Holiday Inn Express Greenville by IHG

Holiday Inn Express Greenville by IHG
2.5 star property
2.3 km from Uptown Greenville
8.4 out of 10, Very good, (1,002 reviews)
"The staff was fantastic!!"
United States
Alicia
The price is ₹10,562
₹11,935 total
includes taxes & fees
15 Nov - 16 Nov
Holiday Inn Express Greenville by IHG
A circular fire pit with seating around it, a covered patio area, and a brick building in the background.

3. Homewood Suites By Hilton Greenville, NC

Homewood Suites By Hilton Greenville, NC
3.0 star property
2.4 km from Uptown Greenville
9.2 out of 10, Wonderful, (441 reviews)
"The room was well cleaned upon arrival, the staff were always professional and nice."
United States
Justin
The price is ₹10,867
₹12,279 total
includes taxes & fees
1 Nov - 2 Nov
Homewood Suites By Hilton Greenville, NC
An indoor swimming pool with clear markings, a "NO DIVING" sign, and a view of parked cars outside.

4. Fairfield Inn & Suites by Marriott Greenville

Fairfield Inn & Suites by Marriott Greenville
3.0 star property
2.4 km from Uptown Greenville
8.6 out of 10, Excellent, (511 reviews)
"Clean room and nice breakfast!"
United States
Frank
The price is ₹12,275
₹13,871 total
includes taxes & fees
25 Oct - 26 Oct
Fairfield Inn & Suites by Marriott Greenville
A spacious lobby with a stone fireplace, comfortable seating, and a bar area.

5. Staybridge Suites Greenville Medical Center by IHG

Staybridge Suites Greenville Medical Center by IHG
3.0 star property
2.3 km from Uptown Greenville
9.2 out of 10, Wonderful, (381 reviews)
"Pool at this property Will be great"
United States
Ashly
The price is ₹11,514
₹13,011 total
includes taxes & fees
18 Oct - 19 Oct
Staybridge Suites Greenville Medical Center by IHG
An outdoor patio area with a fire pit, seating, and umbrellas.

6. Residence Inn by Marriott Greenville

Residence Inn by Marriott Greenville
3.0 star property
2.4 km from Uptown Greenville
8.8 out of 10, Excellent, (539 reviews)
"The facilities were clean and quiet and the breakfast was good."
United States
Steve
The price is ₹12,085
₹13,656 total
includes taxes & fees
22 Oct - 23 Oct
Residence Inn by Marriott Greenville
A Courtyard by Marriott hotel with a covered entrance, outdoor seating, and a landscaped area.

7. Courtyard Marriott Greenville

Courtyard Marriott Greenville
3.0 star property
Medical District, 2.8 km from Uptown Greenville
8.8 out of 10, Excellent, (948 reviews)
"The rooms were clean, and the staff was outstanding. I enjoyed my stay and will visit again."
United States
Wanda
The price is ₹11,243
₹12,704 total
includes taxes & fees
25 Oct - 26 Oct
Courtyard Marriott Greenville
A modern dining area with a large window, a chandelier, and a patterned sofa.

8. Quality Inn Greenville near University

Quality Inn Greenville near University
2.5 star property
2 km from Uptown Greenville
7.4 out of 10, Good, (1,002 reviews)
"Execelente"
United States
Gerson
The price is ₹6,794
₹7,677 total
includes taxes & fees
4 Nov - 5 Nov
Quality Inn Greenville near University
A multi-story hotel with a covered entrance, large windows, and a brick facade.

9. Microtel Inn & Suites by Wyndham Greenville/University Medic

Microtel Inn & Suites by Wyndham Greenville/University Medic
2.0 star property
2.5 km from Uptown Greenville
7.0 out of 10, Good, (1,000 reviews)
"Property was convenient and staff made the stay very enjoyable. Wasn't the cleaners place but room was very clean. Again staff was great!! Also parking and food very close and good"
United States
Samuel
The price is ₹6,066
₹6,855 total
includes taxes & fees
1 Nov - 2 Nov
Microtel Inn & Suites by Wyndham Greenville/University Medic
A hotel room with a desk, two beds, a sofa, a TV, and a coffee machine.

10. Best Western Plus Suites-Greenville

Best Western Plus Suites-Greenville
2.5 star property
3.9 km from Uptown Greenville
9.0 out of 10, Wonderful, (1,000 reviews)
"Wonderful place to stay"
United States
Teresa
The price is ₹10,885
₹12,300 total
includes taxes & fees
1 Nov - 2 Nov
Best Western Plus Suites-Greenville
An outdoor patio with seating, potted plants, and a brick fireplace.

11. Hampton Inn Greenville

Hampton Inn Greenville
2.5 star property
Convention District, 4.3 km from Uptown Greenville
9.0 out of 10, Wonderful, (680 reviews)
"Breakfast was great"
United States
Rose
The price is ₹12,606
₹14,245 total
includes taxes & fees
25 Oct - 26 Oct
Hampton Inn Greenville
A hotel entrance with a prominent 'Super 8' sign, brick facade, and potted plants.

12. Super 8 by Wyndham Greenville

Super 8 by Wyndham Greenville
2.0 star property
2.3 km from Uptown Greenville
6.6 out of 10, (613 reviews)
"Great location and friendly staff"
United States
Sharlene
The price is ₹6,228
₹7,038 total
includes taxes & fees
8 Nov - 9 Nov
Super 8 by Wyndham Greenville
A table set with glassware, plates, and cutlery, and a person arranging the table settings.

13. Holiday Inn Greenville by IHG

Holiday Inn Greenville by IHG
3.0 star property
Convention District, 4.3 km from Uptown Greenville
8.8 out of 10, Excellent, (1,001 reviews)
"Great place, comfortable rooms"
United States
Jonathan
The price is ₹9,135
₹10,322 total
includes taxes & fees
26 Oct - 27 Oct
Holiday Inn Greenville by IHG
A hotel room with two beds, each with patterned bedding, a bedside table with a lamp, and a framed picture on the wall.

14. Motel 6 Greenville, NC – ECU-Medical Center

Motel 6 Greenville, NC – ECU-Medical Center
2.0 star property
2.2 km from Uptown Greenville
6.4 out of 10, (134 reviews)
"Immediately walking to the room, a roach was on the wall, a roach in the refrigerators and the bathroom was next t that clean and presentable. It was a last minute booking abs a game in the area so most hotels were already sold out. I won’t book there again."
United States
Tomeka
The price is ₹6,945
₹7,848 total
includes taxes & fees
18 Oct - 19 Oct
Motel 6 Greenville, NC – ECU-Medical Center
An outdoor patio with seating, a fire pit, and string lights.

15. Hilton Greenville

Hilton Greenville
4.0 star property
Convention District, 4.5 km from Uptown Greenville
8.8 out of 10, Excellent, (580 reviews)
"Best hotel in Greenville when you can’t get the place downtown!"
United States
Sara
The price is ₹14,747
₹16,664 total
includes taxes & fees
25 Oct - 26 Oct
Hilton Greenville
A spacious lobby with a high ceiling, a large window, a ceiling fan, a brown leather sofa, a glass coffee table with flowers, a patterned rug, and a red carpet.

16. Econo Lodge Greenville near University

Econo Lodge Greenville near University
2.0 star property
2.3 km from Uptown Greenville
7.2 out of 10, Good, (477 reviews)
"Nice place, is great for a whole family, close to beaches."
United States
Gerardo
The price is ₹7,234
₹8,174 total
includes taxes & fees
18 Oct - 19 Oct
Econo Lodge Greenville near University
A spacious lobby with a blue sofa, yellow armchairs, a central coffee table, and a wooden balcony railing.

17. Comfort Inn & Suites Greenville Near East Carolina University

Comfort Inn & Suites Greenville Near East Carolina University
2.5 star property
4.9 km from Uptown Greenville
8.6 out of 10, Excellent, (557 reviews)
"Location was comfortable and close to event"
United States
Raymond
The price is ₹10,511
₹11,877 total
includes taxes & fees
25 Oct - 26 Oct
Comfort Inn & Suites Greenville Near East Carolina University
A hotel entrance with a sign reading 'Candlewood Suites.' There are potted plants and a mailbox in the foreground.

18. Candlewood Suites Greenville NC by IHG

Candlewood Suites Greenville NC by IHG
2.5 star property
4.7 km from Uptown Greenville
8.4 out of 10, Very good, (673 reviews)
"Staff was excellent"
United States
scott
The price is ₹8,374
₹9,462 total
includes taxes & fees
1 Nov - 2 Nov
Candlewood Suites Greenville NC by IHG
A clean, well-lit room with a tiled floor, a counter with a cash register, and a sign detailing room rates and policies.

19. Economy Inn of Greenville, NC

Economy Inn of Greenville, NC
2.5 star property
2.1 km from Uptown Greenville
4.4 out of 10, (119 reviews)
"I GOT NONE SMOKING ROOM.. SMELL BAD SO I WANTED MY MONEY HE SAID NO REFUND. COME FIND ITS DRUG MOTEL I WILL DO EVERYTHING N MY POWER GET THAT MOTEL CLOSE DOWN PLACE NEED BE BULL DOZIER OVER"
United States
Walter
The price is ₹5,395
₹6,097 total
includes taxes & fees
18 Oct - 19 Oct
Economy Inn of Greenville, NC
A hotel room with two beds, a red armchair, a sofa, and a desk.

20. Country Inn & Suites by Radisson, Greenville, NC

Country Inn & Suites by Radisson, Greenville, NC
3.0 star property
6.7 km from Uptown Greenville
7.6 out of 10, Good, (932 reviews)
"The check-in was fast and the staff was very welcoming. The room was as listed and expected.; clean and well stocked with plenty of fresh towels. The breakfast staff was accommodating and very friendly;; asking would you like me to make you a waffle, now thats a first. Overall, my stay was very nice tried to book for the following weekend but they were fully booked."
United States
Letitia
The price is ₹8,393
₹9,519 total
includes taxes & fees
1 Nov - 2 Nov
Country Inn & Suites by Radisson, Greenville, NC
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Where to stay in Uptown Greenville

Find the best Uptown Greenville areas for the activities you enjoy most.

University District

While University District isn't home to many top sights, Dowdy–Ficklen Stadium and Williams Arena at Minges Coliseum are some notable places to visit nearby.

Convention District

When in Convention District, you can plan a visit to University Commons and 11 Galleria, some noteworthy sights in the nearby area.

Medical District

If you're looking for some top things to see and do in Medical District and surrounding area, you can visit Arlington Crossing and South Greenville Park.

Westhaven

Westhaven might not have many top sights, but 11 Galleria and University Commons are two attractions nearby that you can check out.

Greenville Heights

If you're looking for some top things to see and do in Greenville Heights and surrounding area, you can visit Williams Arena at Minges Coliseum and Dowdy–Ficklen Stadium.

Top Uptown Greenville Hotel Reviews

Quality Inn Greenville near University

Quality Inn Greenville near University

10/10 Excellent
"No issues."
Tomeka 1-night trip
Posted 1 hour ago
Quality Inn Greenville near University

Frequently asked questions

What is Uptown Greenville like?
Travellers will be sure to find plenty to entertain them in Greenville's Uptown Greenville neighbourhood. Are you looking for Uptown Greenville travel tips? Make sure that you visit Greenville Museum of Art and Town Common while you're in the neighbourhood.
What's a favourite place to stay in Uptown Greenville?
Based on our traveller data, Hilton Garden INN Greenville University is one of the top choices for your stay in Uptown Greenville. This hotel is a short 3-minute walk from East Carolina University, and it offers a restaurant and a 24-hour fitness centre.
If I need to cancel my hotel reservation in Uptown Greenville, will I receive a refund?
Yes, the majority of hotel room reservations are refundable provided that you cancel before the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of the scheduled arrival. If you have a reservation that's non-refundable, it might still be possible to cancel it and be given a refund within a 24-hour period of booking. Enter dates in and click on "Search", then use the "fully refundable" filter to view top deals in Uptown Greenville.
What is there to do around this Greenville neighbourhood?
A few attractions you might want to check out while you're in Uptown Greenville are Greenville Museum of Art and Town Common. Shepherd Memorial Library - Carver Branch and North Pines are also worth a visit when you're out sightseeing in Greenville.