Photo by Samantha B.

Search Luxury Hotels in St. Louis

    calendar shield illustration

    Change your mind

    Book hotels with free cancellation
    deals illustration

    Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in
    bed illustration

    Be picky

    Search almost a million properties worldwide

Check availability on St. Louis Luxury Hotels

Top St. Louis Luxury Hotels

Frequently asked questions

Are you looking for a luxury hotel for your stay in St. Louis?
St. Louis has some interesting things to see and do including Island of Saint-Louis and Parc National de la Langue de Barbarie, so you might want to take in the local sights during your visit.
What's the best luxury place to stay in St. Louis?
Hotel La Residence is a luxury hotel with a rooftop terrace and a deli, and it's a popular choice for Expedia travellers looking for an elegant place to stay.
When can I expect good weather in St. Louis?
Planning for the weather is a good way to make your trip to St. Louis relaxing and enjoyable, especially when you're splurging. The hottest months are usually April and October, with an average temperature of 28°C, while the coldest months are January and February, with an average of 25°C. Average annual precipitation for St. Louis is 274 mm.
What's there to see and do in St. Louis?
Enjoy all that St. Louis has to offer and visit Island of Saint-Louis, Parc National de la Langue de Barbarie and Saint Louis Beach. If you have extra time while you're in the area, you might want to stop by Faidherbe Bridge and Les Ateliers Tësss.