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Check availability on St. Ann Casino Hotels

Tonight
24 Dec - 25 Dec
Tomorrow
25 Dec - 26 Dec
This weekend
26 Dec - 28 Dec
Next weekend
2 Jan - 4 Jan

Our top choices for St. Ann hotels with a casino

Casino
River City Casino & Hotel

River City Casino & Hotel

River City Casino & Hotel
4.0 star property
St. Louis
9.0 out of 10, Wonderful, (1454)
"Awesome place to stay!!"
United States
Kaitlyn
The price is ₹8,521
₹11,223 total
includes taxes & fees
4 Jan - 5 Jan 2026
River City Casino & Hotel
Exterior
Country Inn & Suites by Radisson, St. Charles Historic District

Country Inn & Suites by Radisson, St. Charles Historic District

Country Inn & Suites by Radisson, St. Charles Historic District
2.5 star property
St. Charles Historic District
9.4 out of 10, Exceptional, (1001)
"Everything was great!"
United States
Rita
The price is ₹10,075
₹11,579 total
includes taxes & fees
25 Jan - 26 Jan 2026
Country Inn & Suites by Radisson, St. Charles Historic District
Exterior
Holiday Inn Express St. Louis West - O'Fallon by IHG

Holiday Inn Express St. Louis West - O'Fallon by IHG

Holiday Inn Express St. Louis West - O'Fallon by IHG
2.5 star property
O'Fallon
8.6 out of 10, Excellent, (845)
"A very nice stay with very pleasant staff"
United States
Clifford
The price is ₹8,159
₹9,624 total
includes taxes & fees
4 Jan - 5 Jan 2026
Holiday Inn Express St. Louis West - O'Fallon by IHG
Exterior
Embassy Suites by Hilton St. Louis Downtown

Embassy Suites by Hilton St. Louis Downtown

Embassy Suites by Hilton St. Louis Downtown
4.0 star property
Downtown St. Louis
8.8 out of 10, Excellent, (1251)
"Great stay and staff "
United States
Mykeshia
The price is ₹9,852
₹11,717 total
includes taxes & fees
4 Jan - 5 Jan 2026
Embassy Suites by Hilton St. Louis Downtown
Casino
Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa
4.5 star property
St. Charles
8.4 out of 10, Very good, (1002)
"Clean room, wonderful helpful pleasant staff, amenities, everything was great love staying here!"
United States
Robyn
The price is ₹15,187
₹19,239 total
includes taxes & fees
29 Dec - 30 Dec
Ameristar Casino Resort and Spa
Lobby
The Great Rivers, an Ascend Collection Hotel

The Great Rivers, an Ascend Collection Hotel

The Great Rivers, an Ascend Collection Hotel
3.0 star property
Alton
7.8 out of 10, Good, (760)
"The hotel is being remodeled, so it's hard to give it a fair review."
United States
Stephen
The price is ₹7,544
₹8,599 total
includes taxes & fees
18 Jan - 19 Jan 2026
The Great Rivers, an Ascend Collection Hotel
Indoor pool, open 8:00 AM to 10:00 PM, pool loungers
La Quinta Inn & Suites by Wyndham St Louis Route 66

La Quinta Inn & Suites by Wyndham St Louis Route 66

La Quinta Inn & Suites by Wyndham St Louis Route 66
3.0 star property
St. Louis
8.0 out of 10, Very good, (1004)
"Nice Staff, Clean Rooms, Good Area!!"
United States
Keyaira
The price is ₹8,612
₹10,010 total
includes taxes & fees
5 Jan - 6 Jan 2026
La Quinta Inn & Suites by Wyndham St Louis Route 66
Exterior
Comfort Suites St Charles - St Louis

Comfort Suites St Charles - St Louis

Comfort Suites St Charles - St Louis
2.5 star property
St. Charles
8.4 out of 10, Very good, (1001)
"Nice staff at reception. "
United States
Denise
The price is ₹7,060
₹8,113 total
includes taxes & fees
11 Jan - 12 Jan 2026
Comfort Suites St Charles - St Louis
Front of property
Hyatt Select St. Louis Airport

Hyatt Select St. Louis Airport

Hyatt Select St. Louis Airport
2.5 star property
Woodson Terrace
9.2 out of 10, Wonderful, (1005)
"this is the perfect place to stay the night before going to the airport "
United States
Laurie
The price is ₹11,566
₹13,803 total
includes taxes & fees
30 Dec - 31 Dec
Hyatt Select St. Louis Airport
Premium bedding, desk, iron/ironing board, free cots/infant beds
Super 8 by Wyndham St Charles

Super 8 by Wyndham St Charles

Super 8 by Wyndham St Charles
2.0 star property
St. Charles
8.0 out of 10, Very good, (1000)
"I'd stay at this place again. "
United States
Suzanne
The price is ₹6,783
₹7,795 total
includes taxes & fees
6 Jan - 7 Jan 2026
Super 8 by Wyndham St Charles
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Top St. Ann Hotel Reviews

Hyatt Regency St. Louis at The Arch

Hyatt Regency St. Louis at The Arch

10/10 Excellent
"Hotel is very nice and quiet. Staff was polite and helpful. Great visit!"
Earnest 2-night trip
Posted 1 day ago
Hyatt Regency St. Louis at The Arch

Frequently asked questions

Searching for casino hotels in St. Ann?
Heading to St. Ann for some gaming? You're in luck, because you'll find Hollywood Casino, Ameristar Casino St. Charles, and Horseshoe St. Louis Casino in the area, plus much more to see and do. Visitors enjoy the dining options, bars and breweries. You might want to visit popular sights in the larger area including St. Louis Union Station and Busch Stadium.
How many hotels that are good for gaming are there in St. Ann?
Practise your poker face at one of Expedia's 14 lodging options in St. Ann.
When should I take my casino trip to St. Ann?
You might spend a lot of your holiday inside, but if you're planning to venture beyond the casino, looking at local weather trends is a good idea. The hottest months are usually July and August, with an average temperature of 24°C, while the coldest months are January and February, with an average of 3°C. Average annual precipitation for St. Ann is 1258 mm.
What is there to do in St. Ann?
You can head to Westport Plaza, Saint Louis Galleria Mall or Washington Avenue Historic District to shop for the perfect souvenir. Places like Hollywood Casino Amphitheatre, Blanche M. Touhill Performing Arts Center and St. Louis Art Museum offer a glimpse of local culture. If you're looking for more to see and do, you can add St. Louis Union Station and Busch Stadium to your list.
What are my transportation options for my casino getaway to St. Ann?
Getting around St. Ann is easier with these transportation options: You can fly into the closest airport, which is Lambert-St. Louis International Airport (STL), situated 1.5 mi (2.3 km) from the city centre. If you'd like to venture out around the area, consider renting a car to explore more sights.