A calm lake surrounded by trees and vegetation.

Search Business Hotels in Southwest Illinois

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check availability on Southwest Illinois Business Hotels

This weekend
6 Nov - 8 Nov
Next weekend
13 Nov - 15 Nov

Our top choices for Southwest Illinois business-friendly hotels

A buffet with various food items, including omelets and other dishes, arranged on a counter with a patterned tile backsplash.

1. Holiday Inn Express Hotel & Suites Sparta by IHG

Holiday Inn Express Hotel & Suites Sparta by IHG
2.5 star property
Sparta
9.2 out of 10, Wonderful, (435 reviews)
"Clean property and friendly staff"
United States
Jo Ann
The price is ₹8,356
₹9,273 total
includes taxes & fees
15 Nov - 16 Nov
Holiday Inn Express Hotel & Suites Sparta by IHG
A hotel kitchen with wooden cabinets, a coffee station, and a dining area with tables and chairs.

2. Best Western U. S. Inn

Best Western U. S. Inn
2.5 star property
Nashville
8.6 out of 10, Excellent, (459 reviews)
"Worked well for our short stay."
United States
Steven
The price is ₹11,394
₹12,417 total
includes taxes & fees
3 Nov - 4 Nov
Best Western U. S. Inn
A bar area with a long counter, multiple chairs, and hanging light fixtures.

3. Drury Plaza Hotel Mt. Vernon

Drury Plaza Hotel Mt. Vernon
3.5 star property
Mount Vernon
9.8 out of 10, Exceptional, (1,855 reviews)
"The breakfast was amazing"
United States
Angie
The price is ₹10,539
₹11,886 total
includes taxes & fees
8 Nov - 9 Nov
Drury Plaza Hotel Mt. Vernon
A multi-story hotel with a central entrance, illuminated by exterior lights, and a clear sky in the background.

4. Best Western Plus Centralia Hotel & Suites

Best Western Plus Centralia Hotel & Suites
2.5 star property
Centralia
9.6 out of 10, Exceptional, (686 reviews)
"We stayed here with 2 adults and 3 kids and it was perfect. We highly recommend staying here"
United States
Jeremy
The price is ₹13,199
₹14,780 total
includes taxes & fees
3 Nov - 4 Nov
Best Western Plus Centralia Hotel & Suites
A spacious lobby with a stone fireplace, a seating area with a sofa and chairs, and a television mounted on the wall.

5. SureStay Hotel by Best Western Whittington Rend Lake

SureStay Hotel by Best Western Whittington Rend Lake
2.5 star property
Whittington
8.8 out of 10, Excellent, (1,001 reviews)
"Very clean and everything was perfect!"
United States
Tad
The price is ₹7,263
₹8,061 total
includes taxes & fees
1 Dec - 2 Dec
SureStay Hotel by Best Western Whittington Rend Lake
A hotel lobby with a reception desk, seating area, and a large screen TV.

6. Comfort Suites Mount Vernon

Comfort Suites Mount Vernon
2.5 star property
Mount Vernon
9.0 out of 10, Wonderful, (1,094 reviews)
"Great bathroom"
United States
Bruce and Robin
The price is ₹11,167
₹12,583 total
includes taxes & fees
15 Nov - 16 Nov
Comfort Suites Mount Vernon
A modern spa room with a large hot tub, a glass wall with a reflective pattern, and a ceiling with a skylight.

7. Walker's Bluff Casino Resort

Walker's Bluff Casino Resort
4.5 star property
Carterville
9.4 out of 10, Exceptional, (542 reviews)
"A great place to stay"
United States
Ron
The price is ₹13,798
₹15,313 total
includes taxes & fees
11 Nov - 12 Nov
Walker's Bluff Casino Resort
A hotel room with two beds, a desk with a computer, a chair, a TV, and two wall-mounted lamps.

8. Super 8 by Wyndham Okawville

Super 8 by Wyndham Okawville
2.0 star property
Okawville
7.4 out of 10, Good, (369 reviews)
"Great place to stay on a budget!"
United States
Peter
The price is ₹6,376
₹6,758 total
includes taxes & fees
9 Nov - 10 Nov
Super 8 by Wyndham Okawville
A modern kitchen with wooden cabinets, a refrigerator, a coffee machine, and a microwave. There are red chairs and a table in the dining area.

9. Quality Inn Mount Vernon, IL

Quality Inn Mount Vernon, IL
2.5 star property
Mount Vernon
7.8 out of 10, Good, (722 reviews)
"Clean rooms, complimentary breakfast, great value."
United States
Ryan
The price is ₹6,837
₹7,777 total
includes taxes & fees
15 Nov - 16 Nov
Quality Inn Mount Vernon, IL
A hotel room with a bed, a desk with a chair, a small table, a sofa, a bathtub, and a window with curtains.

10. Baymont by Wyndham Chester IL

Baymont by Wyndham Chester IL
2.5 star property
Chester
8.4 out of 10, Very good, (434 reviews)
"Nice, big building with big, comfy lobby. We were at the end of a long hallway so it was nice and private for us. Woman in charge was very pleasant and competent. Got us checked in right away."
United States
Frederick
The price is ₹7,487
₹8,309 total
includes taxes & fees
15 Nov - 16 Nov
Baymont by Wyndham Chester IL
An outdoor patio area with wicker furniture, a stone pillar, and a glass-enclosed dining area.

11. Holiday Inn Express & Suites Salem by IHG

Holiday Inn Express & Suites Salem by IHG
2.5 star property
Salem
9.4 out of 10, Exceptional, (808 reviews)
"Great location"
United States
John
The price is ₹9,970
₹11,167 total
includes taxes & fees
15 Nov - 16 Nov
Holiday Inn Express & Suites Salem by IHG
A hotel room with two beds, a desk, a television, and a window with a view of the outdoors.

12. Red Bud Country Inn

Red Bud Country Inn
2.5 star property
Red Bud
8.8 out of 10, Excellent, (79 reviews)
"Great value. Clean, spacious room. Minimal continental breakfast; apple juice was past its prime."
United States
James
The price is ₹8,347
₹9,265 total
includes taxes & fees
4 Nov - 5 Nov
Red Bud Country Inn
An indoor swimming pool area with multiple lanes, lounge chairs, and a small seating area.

13. Drury Inn & Suites St. Louis O'Fallon, IL

Drury Inn & Suites St. Louis O'Fallon, IL
3.0 star property
O'Fallon
9.6 out of 10, Exceptional, (1,007 reviews)
"Staff was very friendly"
United States
Karissa
The price is ₹9,684
₹11,232 total
includes taxes & fees
8 Nov - 9 Nov
Drury Inn & Suites St. Louis O'Fallon, IL
A modern dining area with multiple tables and chairs, a kitchen area with appliances, and a ceiling with recessed lighting and a circular light fixture.

14. Best Western Plus MidAmerica Hotel

Best Western Plus MidAmerica Hotel
2.5 star property
Mascoutah
9.0 out of 10, Wonderful, (1,003 reviews)
"Staff was wonderful and the breakfast was good."
United States
Alice
The price is ₹9,567
₹10,904 total
includes taxes & fees
8 Nov - 9 Nov
Best Western Plus MidAmerica Hotel
A covered porch with a metal railing, a red carpet, and a green chair.

15. K-River Motel & Campground

K-River Motel & Campground
2.0 star property
Baldwin
9.0 out of 10, Wonderful, (23 reviews)
"I enjoyed my stay very much. Clean room, comfortable bed, friendly staff and atmosphere. I would recommend this to anyone "
United States
Joyce
The price is ₹6,172
₹6,850 total
includes taxes & fees
4 Nov - 5 Nov
K-River Motel & Campground
A lobby with a sofa, chairs, a fireplace, a clock, and framed pictures on the wall.

16. Fairgrounds Inn

Fairgrounds Inn
2.0 star property
Du Quoin
7.6 out of 10, Good, (447 reviews)
"The establishment is very pleasant. My kids and I enjoyed the indoor swimming pool, and the nice big space in the back of the hotel on there patio. They have two BBQ grills picnic tables at least 5 of them, and just a very"
United States
Kasey
The price is ₹6,687
₹7,422 total
includes taxes & fees
3 Dec - 4 Dec
Fairgrounds Inn
A hotel room with a bed, a desk, a chair, a TV, and a window with curtains.

17. Super 8 by Wyndham Mt. Vernon IL

Super 8 by Wyndham Mt. Vernon IL
2.5 star property
Mount Vernon
7.8 out of 10, Good, (1,001 reviews)
"Everything was clean, nice hotel"
United States
Leslie
The price is ₹6,932
₹7,883 total
includes taxes & fees
8 Nov - 9 Nov
Super 8 by Wyndham Mt. Vernon IL
A large, two-story house with a wrap-around porch and a central tower.

18. The Conner House B&B

The Conner House B&B
3.5 star property
Prairie du Rocher
10.0 out of 10, Exceptional, (22 reviews)
"A pitch perfect stay"
United States
James
The price is ₹14,837
₹16,466 total
includes taxes & fees
3 Nov - 4 Nov
The Conner House B&B
A Comfort Inn & Suites hotel with a covered entrance, multiple floors, and a landscaped front yard.

19. Comfort Inn & Suites Marion I-57

Comfort Inn & Suites Marion I-57
2.5 star property
Marion
9.4 out of 10, Exceptional, (1,001 reviews)
"Clean and comfortable room. Breakfast options were very good!"
United States
Suzan
The price is ₹10,597
₹12,714 total
includes taxes & fees
15 Nov - 16 Nov
Comfort Inn & Suites Marion I-57
An indoor swimming pool with a view of the outside, a hot tub, and a seating area with tables and chairs.

20. DoubleTree by Hilton Mt. Vernon

DoubleTree by Hilton Mt. Vernon
4.0 star property
Mount Vernon
8.4 out of 10, Very good, (908 reviews)
"Nice clean and great staff"
United States
Kenneth
The price is ₹12,143
₹13,666 total
includes taxes & fees
7 Nov - 8 Nov
DoubleTree by Hilton Mt. Vernon
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Top Southwest Illinois Hotel Reviews

Drury Inn & Suites Marion

Drury Inn & Suites Marion

10/10 Excellent
"Our room was clean and the bed comfortable. I used the pool and the hot tub and they were clean. Breakfast was good and plentiful. The hotel location was close to the freeway for easy access."
Geri 1-night trip
Posted 9 hours ago
Drury Inn & Suites Marion

Frequently asked questions

How much do business-friendly hotels in Southwest Illinois cost?
You'll pay between ₹6,758 and ₹12,417 per night for business-friendly hotels in Southwest Illinois. Top deals on stays that cater to work-related travellers are only a click away on Expedia. These prices were available on Expedia within the past 7 days, for a hotel booking with a check-in date within the next year. Prices reflect current offers and availability is subject to change. Additional terms may apply.
What are the best business-friendly hotels in Southwest Illinois?
There are multiple business-friendly hotels in Southwest Illinois with a total average guest review rating of 8.4, so you're sure to discover the perfect place. On your way to O'Fallon? Drury Inn & Suites St. Louis O'Fallon, IL is a top pick with corporate travellers. This 3-stars option has amenities like a swimming pool and WiFi. Hampton Inn O'Fallon also scores top marks from business guests. Take advantage of a swimming pool and an electric car charging station at this 2.5-stars escape in O'Fallon.
How many business-friendly hotels are there in Southwest Illinois?
Southwest Illinois has 105 business-friendly hotels to choose from. Whether you're attending a conference or meeting or simply working remotely, these properties are equipped with the amenities you need to keep you comfortable and productive.
What are the best cheap business-friendly hotels in Southwest Illinois?
When you need to make and close deals on the go in Southwest Illinois, Expedia will help you find the perfect business-friendly hotel. Hampton Inn O'Fallon is a popular budget option in O'Fallon. An electric car charging station and a swimming pool are among its many amenities. In search of low-cost stays in Marion? Comfort Inn & Suites Marion I-57 is recommended by many corporate guests. It comes with conveniences that make it easy to both work and relax, including pool sun loungers and a swimming pool. Business-friendly hotels in Southwest Illinois start at just ₹6,758 a night. Like to sightsee around Southwest Illinois without the high admission prices? Take a break from your work commitments to visit awesome free attractions like St. Clair Bowl in O'Fallon. Marion also has many things to do that don't cost a penny, including Williamson County Historical Museum. This price was available on Expedia within the past 7 days, for a hotel booking with a check-in date within the next year. Prices reflect current offers and availability is subject to change. Additional terms may apply.
Are there any family-friendly hotels in Southwest Illinois that are also business friendly?
If you're travelling for business in Southwest Illinois and bringing family along with you, Expedia will help you locate a cosy and convenient stay. Drury Inn & Suites St. Louis O'Fallon, IL in O'Fallon is the perfect option for those combining work and pleasure. This 3-stars property comes with all the necessary amenities, like complimentary breakfast and a laundry service. Drury Inn & Suites St. Louis Fairview Heights is another terrific choice in O'Fallon. Get the best of both worlds — combine corporate travel and quality time with your family at this 3-stars property. Complimentary breakfast and WiFi are among the conveniences you'll find here. Once you've gotten work out of the way, get out and see O'Fallon with the kids. Popular family-friendly attractions include The Edge and St. Clair Bowl.
Why book your business-friendly hotel in Southwest Illinois with Expedia?
At Expedia, our top task is to help you land the ideal stay at the right price. From upmarket, corporate-friendly properties to affordable motels filled with all the amenities you need, you'll have your next work trip arranged in a few simple clicks.
How can I find cheap business-friendly hotels in Southwest Illinois?
When work takes you to Southwest Illinois, our "business friendly" filter will help you find a suitable hotel. From fast WiFi to meeting rooms and workspaces, they come with the amenities you need for a comfortable and productive stay. Another tip? Narrow your search by your budget and preferred star rating to see the cheapest accommodation.
What is there to do in Southwest Illinois near my business-friendly hotel?
Wherever your travels take you in Southwest Illinois, there's plenty to keep you busy. Staying a few days in O'Fallon? The Edge is a top attraction to include on your itinerary.

Explore a world of travel with Expedia