TOP Adults Only Resorts & Hotels in Southwest Illinois, IL for 2026

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Check availability on Southwest Illinois Adults Only Resorts & Hotels

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Our top choices for Southwest Illinois adults-only hotels

Studio Suite, 2 Queen Beds, Non Smoking | Desk, laptop workspace, blackout curtains, free cots/infant beds

Combined shower/bathtub, hair dryer, towels

1. Super 8 by Wyndham Okawville

Okawville

Peter

₹6,571

₹6,964 total

includes taxes & fees

6 Sept - 7 Sept

Standard Room, 2 Double Beds, Non Smoking | Desk, laptop workspace, iron/ironing board, free WiFi

2. Best Western U. S. Inn

Nashville

James

₹11,435

₹12,461 total

includes taxes & fees

16 Aug - 17 Aug

Pillow-top beds, desk, laptop workspace, blackout curtains

Suite, 1 King Bed, Non Smoking, Refrigerator & Microwave (with Sofabed) | Pillow-top beds, desk, laptop workspace, blackout curtains

3. Best Western Plus MidAmerica Hotel

Mascoutah

Jaysen

₹10,440

₹11,899 total

includes taxes & fees

19 Aug - 20 Aug

Desk, blackout curtains, iron/ironing board, free cots/infant beds

4. Drury Plaza Hotel Mt. Vernon

Mount Vernon

Kirstyn

₹10,577

₹11,929 total

includes taxes & fees

30 Aug - 31 Aug

Standard Room, 1 King Bed | Desk, laptop workspace, blackout curtains, iron/ironing board

5. Holiday Inn Express Hotel & Suites Sparta by IHG

Sparta

Keisha

₹9,640

₹10,698 total

includes taxes & fees

16 Aug - 17 Aug

Suite, 1 King Bed, Non Smoking (One-Bedroom, Honeymoon) | Jetted bathtub

6. Seasons Inn & Suites Highland

Highland

Patricia

₹8,066

₹8,952 total

includes taxes & fees

13 Aug - 14 Aug

In-room safe, blackout curtains, iron/ironing board, free WiFi

7. The Principal Hotel

Columbia

Daniel

₹10,179

₹11,297 total

includes taxes & fees

31 Aug - 1 Sept

Indoor pool, open 8 AM to 10 PM, pool loungers

Standard Room, 2 Queen Beds, Non Smoking, Refrigerator & Microwave | Pillow-top beds, desk, iron/ironing board, cots/infant beds

8. Best Western Plus Centralia Hotel & Suites

Centralia

Corey

₹14,199

₹15,900 total

includes taxes & fees

17 Aug - 18 Aug

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Top Southwest Illinois Hotel Reviews

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Change your mind

Treat yourself

Be picky

Check availability on Southwest Illinois Adults Only Resorts & Hotels

Our top choices for Southwest Illinois adults-only hotels

1. Super 8 by Wyndham Okawville

2. Best Western U. S. Inn

3. Best Western Plus MidAmerica Hotel

4. Drury Plaza Hotel Mt. Vernon

5. Holiday Inn Express Hotel & Suites Sparta by IHG

6. Seasons Inn & Suites Highland

7. The Principal Hotel

8. Best Western Plus Centralia Hotel & Suites

9. SureStay Hotel by Best Western Whittington Rend Lake

10. Drury Inn & Suites St. Louis O'Fallon, IL

Top Southwest Illinois Hotel Reviews

Explore a world of travel with Expedia

Search Adults Only Resorts & Hotels in Southwest Illinois

Change your mind

Treat yourself

Be picky

Check availability on Southwest Illinois Adults Only Resorts & Hotels

Our top choices for Southwest Illinois adults-only hotels

1. Super 8 by Wyndham Okawville

2. Best Western U. S. Inn

3. Best Western Plus MidAmerica Hotel

4. Drury Plaza Hotel Mt. Vernon

5. Holiday Inn Express Hotel & Suites Sparta by IHG

6. Seasons Inn & Suites Highland

7. The Principal Hotel

8. Best Western Plus Centralia Hotel & Suites

9. SureStay Hotel by Best Western Whittington Rend Lake

10. Drury Inn & Suites St. Louis O'Fallon, IL

Top Southwest Illinois Hotel Reviews

Explore a world of travel with Expedia