The Best Hotels in Siesta Isle, Fort Myers Beach - 2026 Updated Prices

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Our top choices for Siesta Isle hotels

A row of turquoise Adirondack chairs with umbrellas, a wooden deck, and a marina in the background.

1. Latitude 26 Waterfront Boutique Resort - Fort Myers Beach

Siesta Isle

Ana

₹9,247 total

includes taxes & fees

1 Oct - 2 Oct

A large, clear swimming pool with multiple lounge areas and palm trees.

2. Margaritaville Beach Resort Fort Myers

2.6 km from Siesta Isle

Michael

₹21,484 total

includes taxes & fees

1 Oct - 2 Oct

A swimming pool with a rock arch structure, a multi-story building with balconies, and palm trees in the background.

3. Pink Shell Beach Resort and Marina

1.8 km from Siesta Isle

Mario

₹27,756 total

includes taxes & fees

21 Oct - 22 Oct

A spacious lobby with a high ceiling, a seating area with a sofa and chairs, a small round table, and a decorative wall with artwork.

4. Hampton Inn & Suites Fort Myers Beach/Sanibel Gateway

2.6 km from Siesta Isle

Robert

₹8,249 total

includes taxes & fees

6 Oct - 7 Oct

An outdoor patio with tables and chairs, umbrellas, and a pool in the background.

5. Holiday Inn Express & Suites Ft Myers Beach-Sanibel Gateway by IHG

2.7 km from Siesta Isle

Gigette

₹9,954 total

includes taxes & fees

5 Oct - 6 Oct

A modern dining area with wooden flooring, white chairs, and large windows offering a view of the beach.

6. Best Western Plus Beach Resort

2.2 km from Siesta Isle

Hassan

₹21,298 total

includes taxes & fees

1 Oct - 2 Oct

A hotel pool area with multiple lounge chairs and umbrellas, surrounded by a fence and palm trees.

7. La Quinta Inn & Suites by Wyndham Ft. Myers-Sanibel Gateway

2.3 km from Siesta Isle

Jorge

₹8,562 total

includes taxes & fees

6 Oct - 7 Oct

A spacious dining area with multiple tables and chairs, large windows, and a modern chandelier.

8. Residence Inn by Marriott Fort Myers Sanibel

2.7 km from Siesta Isle

jennifer

₹10,060 total

includes taxes & fees

6 Oct - 7 Oct

A swimming pool with lounge chairs and umbrellas, surrounded by palm trees and a stone archway.

9. The Lighthouse Resort Inn & Suites

2.4 km from Siesta Isle

Sherrie

₹12,275 total

includes taxes & fees

1 Oct - 2 Oct

A beach view from a balcony with a pool, palm trees, and a building with a balcony.

10. Edison Beach House

2.3 km from Siesta Isle

Angie

₹18,917 total

includes taxes & fees

1 Oct - 2 Oct

A beachfront hotel with a pool, beach, and ocean view.

11. DiamondHead Beach Resort

2.9 km from Siesta Isle

Tiffani

₹24,879 total

includes taxes & fees

1 Oct - 2 Oct

A beach view with rows of empty wine glasses lined up on a balcony.

12. Lani Kai Beachfront Resort

2.7 km from Siesta Isle

ROBERT

₹15,678 total

includes taxes & fees

12 Oct - 13 Oct

A balcony with a wicker sofa, a yellow table, and a potted plant.

13. Latitude 26 Waterfront Resort & Marina

1.1 km from Siesta Isle

Sebastian

₹13,235 total

includes taxes & fees

19 Oct - 20 Oct

A marina with boats docked, surrounded by palm trees and a building with a red-tiled roof.

14. Matanzas Inn Bayside Resort and Marina

2.1 km from Siesta Isle

Janine

₹19,623 total

includes taxes & fees

27 Oct - 28 Oct

A balcony with tables set for dining, overlooking a beach with palm trees and the ocean.

15. The Bay Inn at Lani Kai

2.7 km from Siesta Isle

Linet

₹12,640 total

includes taxes & fees

1 Oct - 2 Oct

A hotel room with a large bed, two bedside tables with lamps, a nightstand, and a window with curtains.

16. Candlewood Suites Fort Myers Sanibel Gateway by IHG

4.9 km from Siesta Isle

John

₹6,315 total

includes taxes & fees

6 Oct - 7 Oct

A waterfront hotel with multiple buildings, a dock, and a calm body of water reflecting the structures.

17. Marriott Sanibel Harbour Resort & Spa

5.7 km from Siesta Isle

Charles

₹27,247 total

includes taxes & fees

14 Oct - 15 Oct

A hotel room with two beds, a wooden headboard, a nightstand with a lamp, and a window with curtains.

18. Holiday Inn Express Cape Coral-Fort Myers Area by IHG

9.7 km from Siesta Isle

Brett R

₹11,023 total

includes taxes & fees

6 Oct - 7 Oct

An indoor swimming pool with clear water, a lifeguard station, and a seating area with chairs.

19. Comfort Inn & Suites Fort Myers Airport

18.1 km from Siesta Isle

Carmen

₹7,693 total

includes taxes & fees

6 Oct - 7 Oct

An outdoor patio with a barbecue area, seating, and string lights.

20. Homewood Suites by Hilton Fort Myers Airport/FGCU

17 km from Siesta Isle

Kieran

₹12,199 total

includes taxes & fees

18 Oct - 19 Oct

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Where to stay in Siesta Isle

Find the best Siesta Isle areas for the activities you enjoy most.

A sunset over a calm sea with trees framing the view.

Mid Island

While visiting Mid Island, you might make a stop by sights like Estero Boulevard Beach and Sterling Ave Beach.

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A pier extending into the water with two gazebos at the end, under a sunset sky.

South Island

While visiting South Island, you might make a stop by sights like Santini Marina Shopping Plaza and Castle Beach.

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A coastal town with a marina, residential buildings, and a clear view of the ocean.

TP Hill's

When in TP Hill's, you can plan a visit to Key West Express and Estero Boulevard Beach, some noteworthy sights in the nearby area.

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A beach at sunset with a pink and purple sky, people walking, and a lifeguard tower in the distance.

Downtown Fort Myers Beach

If you're spending some time in Downtown Fort Myers Beach, Lynn Hall Memorial Park and Estero Boulevard Beach are top sights worth seeing.

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A coastal town with a beach, buildings, and a road.

Winklers

Winklers might not have many top sights, but Key West Express and Estero Boulevard Beach are two attractions nearby that you can check out.

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Top Siesta Isle Hotel Reviews

Hilton Garden Inn Ft Myers

8/10 Good

"Staff was helpful and friendly, the room was clean and the property is well maintained"

Hyatt Vacation Club at Coconut Cove, Bonita Springs

10/10 Excellent

"Best resort/vacation I’ve ever had in Florida. Four pools a lazy river two hot tubs two bars and a restaurant. And the private island! We will definitely be back. The staff was beyond nice and courteous. Do not hesitate to book a stay here."

Pink Shell Beach Resort and Marina

10/10 Excellent

"It was absolutely fantastic! We will be there next September and will be bringing more family with us. Please remember me if you have any special offers. The only thing that would have made it better is we were staying in the third building with the adult pool and we would love to have gone in and out of the gate by our building. It was a long walk around by the first building."

Frequently asked questions

What is Siesta Isle like?

Travellers will be sure to find plenty to entertain them in Fort Myers Beach's Siesta Isle neighbourhood. Consider a visit to San Carlos Bay - Bunche Beach Preserve as part of your Siesta Isle travel plans.

Where is the best place to stay in Siesta Isle?

Based on our traveller data, Latitude 26 Waterfront Boutique Resort - Fort Myers Beach is one of the top choices for your stay in Siesta Isle. This hotel offers a marina and free breakfast.

How many hotels will I find in the Siesta Isle area?

If you're searching for places to stay in Fort Myers Beach, Expedia has something to meet your needs with 27 Siesta Isle hotels and other accommodation options to choose from.

If I need to cancel my hotel reservation in Siesta Isle, will I receive a refund?

Yes! You'll find that most hotel reservations are refundable provided that you cancel prior to the accommodation's cancellation deadline, which is usually within 24-48 hours of your check-in date. If you booked a non-refundable reservation, it may still be possible to cancel it and be given a refund within a 24-hour period of your booking. Enter your dates, click on "Search", then use the "fully refundable" filter to view the best deals in Siesta Isle.

What are the top things to see and do in Siesta Isle?

San Carlos Bay - Bunche Beach Preserve is an attraction you might want to check out while you're in Siesta Isle. Key West Express and Bunche Beach are also worth a visit when you're out sightseeing in Fort Myers Beach.

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Our top choices for Siesta Isle hotels

1. Latitude 26 Waterfront Boutique Resort - Fort Myers Beach

2. Margaritaville Beach Resort Fort Myers

3. Pink Shell Beach Resort and Marina

4. Hampton Inn & Suites Fort Myers Beach/Sanibel Gateway

5. Holiday Inn Express & Suites Ft Myers Beach-Sanibel Gateway by IHG

6. Best Western Plus Beach Resort

7. La Quinta Inn & Suites by Wyndham Ft. Myers-Sanibel Gateway

8. Residence Inn by Marriott Fort Myers Sanibel

9. The Lighthouse Resort Inn & Suites

10. Edison Beach House

11. DiamondHead Beach Resort

12. Lani Kai Beachfront Resort

13. Latitude 26 Waterfront Resort & Marina

14. Matanzas Inn Bayside Resort and Marina

15. The Bay Inn at Lani Kai

16. Candlewood Suites Fort Myers Sanibel Gateway by IHG

17. Marriott Sanibel Harbour Resort & Spa

18. Holiday Inn Express Cape Coral-Fort Myers Area by IHG

19. Comfort Inn & Suites Fort Myers Airport

20. Homewood Suites by Hilton Fort Myers Airport/FGCU

Where to stay in Siesta Isle

Mid Island

South Island

TP Hill's

Downtown Fort Myers Beach

Winklers

Top Siesta Isle Hotel Reviews

Hilton Garden Inn Ft Myers

Frequently asked questions

Explore a world of travel with Expedia