Weather will likely play an important role when you plan your trip to Santo Domingo, but bear in mind that cheaper options are usually available when the weather isn't as good. The hottest months are usually March and April, with an average temperature of 25°C, while the coldest months are November and December, with an average of 24°C. The rainiest months in Santo Domingo are September, June, October and August, with each month seeing an average of 236 mm of rainfall.