Search Spa Hotels in Santiago

Start date: Check-in selected.
To Date
End date: Check-out

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check availability on Santiago Spa Hotels

Our top choices for Santiago hotels with a spa

Terrace/patio
Hotel Mykonos Panama

Hotel Mykonos Panama

Hotel Mykonos Panama
3.5 star property
Nuevo Santiago
8.8 out of 10, Excellent, (536)
"Everything was nice room, staff, amenities!"
United States
Daniel
The price is ₹7,640
₹8,404 total
includes taxes & fees
14 Dec - 15 Dec
Hotel Mykonos Panama
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Top Santiago Hotel Reviews

Hotel Mykonos Panama

Hotel Mykonos Panama

10/10 Excellent
"Everything was nice room, staff, amenities!"
Daniel 1-night trip
Posted 11 days ago
Hotel Mykonos Panama
Hotel Gran David

Hotel Gran David

10/10 Excellent
"Everything was very good"
William 1-night trip
Posted 3 weeks ago
Hotel Gran David

Explore a world of travel with Expedia

Frequently asked questions

Looking for a spa hotel in Santiago?
Book one of our fantastic spa hotels and treat yourself from the moment you arrive. Enjoy the cathedral and bars in Santiago—your day trip starts here. Enjoy the shops and many popular restaurants during your holiday. Hotels with spas are the perfect way to break out of your daily routine and add a layer of luxury to your holiday.
What's there to see and do in Santiago?
Take in the sights and attractions that Santiago offers with a visit to Catedral of Santiago Apostol, Omar Torrijos Herrera Stadium and Plaza Banconal. If you have a bit of extra time while you're in the area, you might want to check out Parque Acuatico Italia Guadalupe Panama and Los Pozos Termales.
What is a Santiago spa hotel?
Spa hotels in Santiago provide lodging and have a full on-site spa offering services including massages as well as beauty treatments. Some also offer in-room treatments. Spa hotels are great for rest, rejuvenation and relaxation.