Santee Hotels

Start date: Check-in selected.
To Date
End date: Check-out

    Change your mind

    Book hotels with free cancellation

    Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

    Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
18 Oct - 19 Oct
Tomorrow
19 Oct - 20 Oct
Next weekend
24 Oct - 26 Oct
In two weeks
31 Oct - 2 Nov

Filter by

Guest rating
Guest rating
Star rating

Top 10 Santee hotels and places to stay

32-inch LCD TV with digital channels, TV
Lewis and Clark Resort
Lewis and Clark Resort
2.5 star property
8.8 out of 10, Excellent, (268)
"nice place"
United States
Jeanne
Lewis and Clark Resort
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Top Santee Hotel Reviews

Frequently asked questions

If I need to cancel my hotel reservation in Santee, will I receive a refund?
Yes, you'll find most hotel reservations are fully refundable if cancelled prior to the accommodation's cancellation deadline, which is usually within 24-48 hours of your arrival date. If you have a reservation that's non-refundable, it may still be possible to cancel it and get a refund within 24 hours of your booking. Filter your search by fully refundable to find flexible hotel deals in Santee.
What is staying in Santee like?
Those travelling to Santee will definitely enjoy the sights to see and things to do. There are 61 hotels and other accommodation options in the surrounding area. Find out more about Santee.
What is there to see in Santee?
A favourite place to visit is Lewis and Clark Lake. You'll also find Niobrara State Park and Lewis and Clark Recreation Area in the area. Take a look at what more there is to see and do in Expedia's Santee guide.
What's the seasonal weather in Santee?
The hottest months are usually July and August, with an average temperature of 22°C, while the coldest months are January and February, with an average of -3°C. The snowiest months in Santee are January, December, October and March, with each month seeing an average of 20 cm of snowfall.

Explore a world of travel with Expedia