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10 Dec - 11 Dec
Tomorrow
11 Dec - 12 Dec
This weekend
12 Dec - 14 Dec
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19 Dec - 21 Dec

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Our top choices for Santa María hotels

Exterior
One Oaxaca Centro Hotel

One Oaxaca Centro Hotel

One Oaxaca Centro Hotel
3.0 star property
Ruta Independencia, 2.5 km from Santa María
8.8 out of 10, Excellent, (1002)
"Very good hotel"
United States
Hugo
The price is ₹7,120
₹8,486 total
includes taxes & fees
14 Dec - 15 Dec
One Oaxaca Centro Hotel
Building design
Quinta Real Oaxaca

Quinta Real Oaxaca

Quinta Real Oaxaca
4.5 star property
Ruta Independencia, 1.9 km from Santa María
9.6 out of 10, Exceptional, (1000)
"We loved everything about our stay at Quinta Real in Oaxaca, highly recommend, would definitely stay again!"
United States
Valerie
The price is ₹26,450
₹31,476 total
includes taxes & fees
14 Dec - 15 Dec
Quinta Real Oaxaca
Restaurant
Capital O Posada La Casa De La Tia, Oaxaca

Capital O Posada La Casa De La Tia, Oaxaca

Capital O Posada La Casa De La Tia, Oaxaca
3.0 star property
Ruta Independencia, 2 km from Santa María
7.8 out of 10, Good, (195)
"You can walk around downtown "
United States
GORGONIO
The price is ₹3,991
₹5,188 total
includes taxes & fees
7 Jan - 8 Jan 2026
Capital O Posada La Casa De La Tia, Oaxaca
Garden
Hotel Hacienda

Hotel Hacienda

Hotel Hacienda
3.5 star property
3.1 km from Santa María
9.0 out of 10, Wonderful, (1005)
"Super friendly and helpful staff, clean room and very good food at the restaurant!!!"
Mexico
Carlos
The price is ₹5,042
₹6,000 total
includes taxes & fees
13 Dec - 14 Dec
Hotel Hacienda
Terrace/patio
LePetit

LePetit

LePetit
2.5 star property
Ruta Independencia, 2.2 km from Santa María
9.4 out of 10, Exceptional, (21)
"The staff is amazing"
United States
Carmen
The price is ₹8,303
₹9,881 total
includes taxes & fees
11 Dec - 12 Dec
LePetit
Outdoor dining
Happy Express Hotel

Happy Express Hotel

Happy Express Hotel
2.5 star property
Oaxaca Centro, 1.8 km from Santa María
9.0 out of 10, Wonderful, (319)
"Nice and clean close to everything easy walking Quiet, comfortable bed and pillows "
United States
MIRIAM
Happy Express Hotel
Outdoor pool
Hotel Victoria Oaxaca

Hotel Victoria Oaxaca

Hotel Victoria Oaxaca
3.5 star property
0.8 km from Santa María
8.8 out of 10, Excellent, (1000)
"Good breakfast at the restaurant. Nice setting. Friendly front desk staff."
Canada
David
The price is ₹6,544
₹7,787 total
includes taxes & fees
16 Dec - 17 Dec
Hotel Victoria Oaxaca
Terrace/patio
Casa de los Frailes Hotel

Casa de los Frailes Hotel

Casa de los Frailes Hotel
3.0 star property
Ruta Independencia, 1.9 km from Santa María
9.2 out of 10, Wonderful, (363)
"Good location close to the centre but on a fairly quiet street. Large rooms, decent shower. "
United Kingdom
Richard
The price is ₹6,534
₹7,776 total
includes taxes & fees
16 Dec - 17 Dec
Casa de los Frailes Hotel
Courtyard
Grand Fiesta Americana Oaxaca

Grand Fiesta Americana Oaxaca

Grand Fiesta Americana Oaxaca
5.0 star property
Ruta Independencia, 2 km from Santa María
9.6 out of 10, Exceptional, (665)
"Great staff, beautiful rooms, wonderful food. Also perfect location."
United States
John Lester
The price is ₹19,311
₹23,016 total
includes taxes & fees
15 Dec - 16 Dec
Grand Fiesta Americana Oaxaca
Exterior
Casa Los Cantaros Hotel Boutique

Casa Los Cantaros Hotel Boutique

Casa Los Cantaros Hotel Boutique
3.5 star property
Reforma, 1.8 km from Santa María
9.4 out of 10, Exceptional, (264)
"Nice staff and huge room with all the amenities."
United States
Celia
The price is ₹6,534
₹7,776 total
includes taxes & fees
11 Dec - 12 Dec
Casa Los Cantaros Hotel Boutique
Lunch and dinner served
Casa De Sierra Azul

Casa De Sierra Azul

Casa De Sierra Azul
3.5 star property
Oaxaca Centro, 2.2 km from Santa María
9.2 out of 10, Wonderful, (898)
"Hospitality was the best. Great location with a lot of shops and Zocalo at walkable distance. rooms were beautiful and comfortable "
United States
Brian
Casa De Sierra Azul
Reception
Marqués Oaxaca - Hotel

Marqués Oaxaca - Hotel

Marqués Oaxaca - Hotel
2.0 star property
2.5 km from Santa María
7.2 out of 10, Good, (105)
"Staff was friendly, & helpful. The location was perfect! Everything was in walking distance, but if you needed a cab the hotel gladly arranged one for you. "
United States
Daisy
The price is ₹3,289
₹3,914 total
includes taxes & fees
18 Dec - 19 Dec
Marqués Oaxaca - Hotel
Exterior
Hotel Boutique Parador San Miguel

Hotel Boutique Parador San Miguel

Hotel Boutique Parador San Miguel
3.0 star property
Ruta Independencia, 1.8 km from Santa María
9.4 out of 10, Exceptional, (777)
"Was one of the best hotels, clean the people were awesome and helped whenever needed"
United States
Asokaraj
The price is ₹11,488
₹13,671 total
includes taxes & fees
7 Jan - 8 Jan 2026
Hotel Boutique Parador San Miguel
Property grounds
Hotel Trebol

Hotel Trebol

Hotel Trebol
3.0 star property
Oaxaca Centro, 2.1 km from Santa María
9.2 out of 10, Wonderful, (1008)
"Amazing staff and accommodations will be coming back"
United States
Christopher Joel Romo
The price is ₹10,505
₹12,501 total
includes taxes & fees
5 Jan - 6 Jan 2026
Hotel Trebol
Terrace/patio
Hotel Danibaan

Hotel Danibaan

Hotel Danibaan
3.0 star property
Del Ex-marquezado, 1.1 km from Santa María
9.4 out of 10, Exceptional, (169)
"Clean Gustavo and staff were very nice and i slept so well. It felt like home away from home. "
United States
Marisol
The price is ₹4,922
₹5,857 total
includes taxes & fees
11 Dec - 12 Dec
Hotel Danibaan
Coffee shop
Hotel Boutique Naura Centro

Hotel Boutique Naura Centro

Hotel Boutique Naura Centro
3.5 star property
Oaxaca Centro, 2.2 km from Santa María
9.2 out of 10, Wonderful, (978)
"wonderful staff and great amenities. Delicious food in their restaurant + cafe."
United States
Edna
Hotel Boutique Naura Centro
Standard Double Room, 1 Double Bed | Desk, laptop workspace, free WiFi, bed sheets
HOTEL POSADA DON MATIAS

HOTEL POSADA DON MATIAS

HOTEL POSADA DON MATIAS
2.0 star property
Oaxaca Centro, 2 km from Santa María
9.0 out of 10, Wonderful, (190)
"It was a quiet place."
United States
Consuelo
The price is ₹3,026
₹3,601 total
includes taxes & fees
8 Jan - 9 Jan 2026
HOTEL POSADA DON MATIAS
Hallway
Casa Antonieta

Casa Antonieta

Casa Antonieta
3.5 star property
Oaxaca Centro, 2.1 km from Santa María
10.0 out of 10, Exceptional, (59)
"A lovely spot all around. "
Canada
Kelly
The price is ₹32,632
₹38,832 total
includes taxes & fees
7 Jan - 8 Jan 2026
Casa Antonieta
Terrace/patio
Hotel Real Alma

Hotel Real Alma

Hotel Real Alma
3.5 star property
Oaxaca Centro, 1.8 km from Santa María
9.0 out of 10, Wonderful, (406)
"Cozy and comfortable hotel. Very clean and staff was very nice and friendly ready to help you with any questions."
United States
Julia
The price is ₹7,573
₹9,011 total
includes taxes & fees
8 Jan - 9 Jan 2026
Hotel Real Alma
Terrace/patio
Casa de Adobe Gallery & Luxury Boutique

Casa de Adobe Gallery & Luxury Boutique

Casa de Adobe Gallery & Luxury Boutique
4.0 star property
San Felipe del Agua, 3.1 km from Santa María
9.0 out of 10, Wonderful, (177)
"Hotel was very clean, great food, and very friendly staff! "
United States
ANGELICA
Casa de Adobe Gallery & Luxury Boutique
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Where to stay in Santa María

Find the best Santa María areas for the activities you enjoy most.
Oaxaca showing a city
Photo by PhotoJoy
Open Photo by PhotoJoy

Oaxaca Centro

Churches, museums and art galleries are some highlights of Oaxaca Centro. Make a stop by Macedonio Alcalá Theater or Oaxaca Textile Museum while you're exploring.

Ruta Independencia

While visiting Ruta Independencia, you might make a stop by sights like Oaxaca Ethnobotanical Garden and Jardín Etnobotánico.

Jalatlaco

While Jalatlaco isn't home to many top sights, El Llano Park and Oaxaca Ethnobotanical Garden are some notable places to visit nearby.

Reforma

While visiting Reforma, you might make a stop by sights like Plaza Mazari and Plaza Parque.

San Agustín Yatareni

San Agustín Yatareni might not have many top sights, but El Llano Park and Oaxaca Ethnobotanical Garden are two attractions nearby that you can check out.

Top Santa María Hotel Reviews

Holiday Inn Express Oaxaca-Centro Historico by IHG

Holiday Inn Express Oaxaca-Centro Historico by IHG

10/10 Excellent
"The room was very. The staff are very helpful. The hotel location is in a quiet area."
Evelyn 2-night trip
Posted 2 days ago
Holiday Inn Express Oaxaca-Centro Historico by IHG

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Frequently asked questions

What is Santa María like?
Travellers to the Santa María neighbourhood in Oaxaca will be sure to enjoy their stay.
If I need to cancel my hotel reservation in Santa María, will I receive a refund?
Yes, you'll find most room reservations are fully refundable if you cancel prior to the hotel's cancellation deadline, which is often 24 or 48 hours before your arrival date. If your reservation is non-refundable, you may still be able to cancel and receive a refund within a 24-hour period of booking. Add your dates and click on "Search", then filter by "fully refundable" to review the best options available in Santa María.
What is there to do in this Oaxaca neighbourhood?
Cerro del Fortín, Parque Juarez El Llano and Auditorio Guelaguetza are just a few of the places to visit in and around Santa María. While you're out sightseeing in Oaxaca, make sure that you visit other sights such as Ex-Convento de Santa Catalina or El Mirador.